PIPA572205

USP13 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572205-Each-of-1 In Stock ₹ 44,705.10

PIPA572205 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

USP13

Classification

Polyclonal

Conjugate

Unconjugated

Gene

USP13

Gene Alias

2700071E21Rik; AI848077; Deubiquitinating enzyme 13; Isopeptidase T-3; ISOT3; IsoT-3; Ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific peptidase 13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T-3); Ubiquitin thioesterase 13; ubiquitin thiolesterase 13; ubiquitin-specific-processing protease 13; usp13; wu:fc61g08

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

558011

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.86 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

F1QFS9

Gene Symbols

USP13

Immunogen

KLH conjugated synthetic peptide between 387-420 amino acids from the Central region of DANRE usp13

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Zebrafish

Product Type

Antibody

Isotype

IgG

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Description

  • Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum-associated degradation (ERAD)
  • Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes
  • Also deubiquitinates USP10, an essential regulator of p53/TP53 stability
  • In turn, PIK3C3/VPS34-containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13
  • Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD)
  • Also regulates ERAD through the deubiquitination of UBL4A a component of the BAG6/BAT3 complex
  • Mediates stabilization of SIAH2 independently of deubiquitinase activity: binds ubiquitinated SIAH2 and acts by impairing SIAH2 autoubiquitination
  • Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains
  • In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly
  • Able to cleave ISG15 in vitro; however, additional experiments are required to confirm such data
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA572205

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Antigen:
USP13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP13

Gene Alias:
2700071E21Rik; AI848077; Deubiquitinating enzyme 13; Isopeptidase T-3; ISOT3; IsoT-3; Ubiquitin carboxyl-terminal hydrolase 13; ubiquitin specific peptidase 13; ubiquitin specific peptidase 13 (isopeptidase T-3); ubiquitin specific protease 13 (isopeptidase T-3); Ubiquitin thioesterase 13; ubiquitin thiolesterase 13; ubiquitin-specific-processing protease 13; usp13; wu:fc61g08

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
558011

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.86 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
F1QFS9

Gene Symbols:
USP13

Immunogen:
KLH conjugated synthetic peptide between 387-420 amino acids from the Central region of DANRE usp13

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG

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PIPA572206

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Antigen:
SH3BP4A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
sh3bp4a

Gene Alias:
SH3 binding protein-4; SH3 domain-binding protein 4-A; sh3bp4; sh3bp4 protein; sh3bp4a; SH3-domain binding protein 4; SH3-domain binding protein 4a; si:dkey-110p14.1; src homology 3 binding protein 4; truncated SH3 binding domain protein 4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
403082

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
2.76 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q1LVQ2

Gene Symbols:
sh3bp4a

Immunogen:
KLH conjugated synthetic peptide between 132-165 amino acids from the N-terminal region of DANRE sh3bp4a

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG

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PIPA572208

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Antigen:
HBAE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
hbae1

Gene Alias:
ae1; alphae1globin; dZ118J2.6; embryonic alpha globin e1; etID40432.3; globin alphae1; HbA; hba2; HBA2r; HBAA1; hbae1; hbae1.1; hemoglobin alpha embryonic-1; hemoglobin alpha-2 chain; hemoglobin, alpha embryonic 1; hemoglobin, alpha embryonic 1.1; si:by119c3.1; si:by119c3.3; SI:dZ118J2.10; SI:dZ118J2.8; si:xx-119c3.3; wu:fa12a11; wu:fb74f06; zgc:86936

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
30597

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.49 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
0

Gene Symbols:
hbae1

Immunogen:
KLH conjugated synthetic peptide between 46-80 amino acids from the Central region of DANRE hbae1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG

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PIPA572209

--


Antigen:
SRMS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SRMS

Gene Alias:
A230069J08Rik; C20orf148; dJ697K14.1; PTK70; src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; SRM; SRMS; Tyrosine-protein kinase Srms

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20811

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q62270

Gene Symbols:
SRMS

Immunogen:
KLH conjugated synthetic peptide between 113-147 amino acids from the Central region of Mouse Srms

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG