PIPA572246

MC4R Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572246-Each-of-1 In Stock ₹ 44,705.10

PIPA572246 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MC4R

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MC4R

Gene Alias

MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

286833

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

B0V1P1

Gene Symbols

MC4R

Immunogen

KLH conjugated synthetic peptide between 25-57 amino acids from the human region of DANRE mc4r

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Zebrafish

Product Type

Antibody

Isotype

IgG

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Description

  • Expression of MC4R has been reported in brain
  • Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes
  • G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
  • All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
  • An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
  • Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
  • This &quoteturn-off&quote activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
  • Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Compare Similar Items

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Thermo Scientific

PIPA572246

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Antigen:
MC4R

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MC4R

Gene Alias:
MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
286833

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
B0V1P1

Gene Symbols:
MC4R

Immunogen:
KLH conjugated synthetic peptide between 25-57 amino acids from the human region of DANRE mc4r

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572251

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Antigen:
Plet1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plet1

Gene Alias:
0610037B23Rik; 1600029D21Rik; AA407923; AgK114; Antigen mAgK114; AU043048; C11orf34; placenta expressed transcript 1; placenta-expressed transcript 1 protein; Plet1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
76509

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8VEN2

Gene Symbols:
Plet1

Immunogen:
KLH conjugated synthetic peptide between 82-115 amino acids from the Central region of Mouse Plet1

Quantity:
80 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572255

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Antigen:
AKR7L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKR7L

Gene Alias:
AFAR3; AFB1 aldehyde reductase 3; AFB1-AR 3; AFB1-AR3; Aflatoxin B1 aldehyde reductase member 4; AKR7A4; AKR7L; aldo-keto reductase family 7 like (gene/pseudogene); Aldoketoreductase 7-like

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
246181

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.44 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8NHP1

Gene Symbols:
AKR7L

Immunogen:
KLH conjugated synthetic peptide between 32-64 amino acids from human AKR7L

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA572258

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Antigen:
WACA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
waca

Gene Alias:
wac; waca; wu:fc13f04; wu:fj68f01; WW domain containing adaptor with coiled-coil; WW domain containing adaptor with coiled-coil a; WW domain-containing adapter protein with coiled-coil; WW domain-containing adapter with a coiled-coil region; zgc:55755

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
323904

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.77 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q7ZUK7

Gene Symbols:
waca

Immunogen:
KLH conjugated synthetic peptide between 487-519 amino acids from DANRE waca

Quantity:
80 μL

Primary or Secondary:
Primary

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG