PIPA572554

ATF6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572554-Each-of-1 In Stock ₹ 44,705.10

PIPA572554 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ATF6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF6

Gene Alias

9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1388, 22926

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.4 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P18850, Q99941

Gene Symbols

ATF6, ATF6B

Immunogen

KLH conjugated synthetic peptide between 350-377 amino acids of human ATF6

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes
  • It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3')
  • Binding to ERSE requires binding of NF-Y to ERSE
  • ATF6 could also be involved in activation of transcription by the serum response factor
  • ATF6 exists as a homodimer and heterodimer with ATF6 beta
  • The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC)
  • It Interacts also with the transcription factors GTF2I, YY1 and SRF
  • Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
  • The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE
  • During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis
  • The cleavage seems to be performed sequentially by site-1 and site-2 proteases
  • ATF6 is N-glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA572554

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Antigen:
ATF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6

Gene Alias:
9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1388, 22926

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
KLH conjugated synthetic peptide between 350-377 amino acids of human ATF6

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA572569

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Antigen:
D4 Dopamine Receptor

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DRD4

Gene Alias:
AW125663; D(2C) dopamine receptor; D(4) dopamine receptor; D4DR; D4R; D4RA; Dopamine 4 receptor; Dopamine D4 receptor; dopamine receptor 4; dopamine receptor D4; DRD4; Drd-4; seven transmembrane helix receptor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13491, 1815

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P21917, P51436

Gene Symbols:
DRD4

Immunogen:
KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA572571

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Antigen:
DCT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCT

Gene Alias:
Dct; DOPAchrome conversion factor; dopachrome delta isomerase; dopachrome delta-isomerase; DOPAchrome isomerase; DOPAchrome oxidoreductase; dopachrome tautomerase; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); DT; hypothetical protein LOC664745; L-dopachrome Delta-isomerase; L-dopachrome isomerase; L-dopachrome tautomerase; melanogenic enzyme; tyrosinase-related protein 2; trp2; RGD1564975; slaty; SLATY locus protein; slt; trp2; TRP-2; tyrosinase related protein 2; tyrosinase related protein-2; tyrosinase-related protein 2; tyrosinase-related protein-2; tyrosine-related protein 2; Tyrp2; Tyrp-2; zgc:109860

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1638

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P40126

Gene Symbols:
DCT

Immunogen:
KLH conjugated synthetic peptide between 62-89 amino acids from the N-terminal region of human DCT

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA572579

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Antigen:
TAZ

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TAZ

Gene Alias:
2310058J06Rik; 2610021I22Rik; 5031411C02Rik; 9130012G04Rik; AW107266; AW552613; Barth syndrome); BTHS; C78399; cardiomyopathy, dilated 3A (X-linked); CMD3A; EFE; EFE2; endocardial fibroelastosis 2; FLJ27390; G4.5; HGNC:11577; LVNCX; OTTHUMP00000061673; protein G4.5; Tafazzin; tafazzin (cardiomyopathy, dilated 3A (X-linked); tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome); Taz; Taz1; transcriptional coactivator with PDZ binding motif; transcriptional co-activator with PDZ-binding motif; transcriptional coactivator with PDZ-binding motif; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ); WW domain containing transcription regulator 1; WW domain-containing transcription regulator protein 1; Wwtr1; XAP-2; XX-FW83563B9.3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6901

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q16635

Gene Symbols:
TAZ

Immunogen:
KLH conjugated synthetic peptide between 32-60 amino acids from the N-terminal region of human TAZ

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG