PIPA572826

Nephrin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572826-Each-of-1 In Stock ₹ 50,394.84

PIPA572826 - Each of 1

₹ 50,394.84

In Stock

Quantity

1

Base Price: ₹ 50,394.84

GST (18%): ₹ 9,071.071

Total Price: ₹ 59,465.911

Antigen

Nephrin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Nphs1

Gene Alias

CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4868, 54631

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O60500, Q9QZS7

Gene Symbols

Nphs1

Immunogen

Nephrin antibody for a 15 amino acid peptide near the carboxy terminus of human Nephrin. The immunogen is within amino acids 1100 - 1150 of Nephrin.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease
  • Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss
  • Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2
  • Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process
  • Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier
  • Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis
  • Three novel podocyte proteins, Podocin, Nephrin and alpha Actinin 4 have been identified in congenital and experimental models of proteinuria
  • The role of Nephrin in anti apoptotic activity in podocyte slit diaphragm is believed to be associated with vascular endothelial derived growth factors VEGF signaling
  • Nephrin seems to play a role in the development or function of the kidney glomerular filtration barrier and it may anchor the podocyte slit diaphragm to the actin cytoskeleton.

Compare Similar Items

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Img

Thermo Scientific

PIPA572826

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Antigen:
Nephrin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nphs1

Gene Alias:
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4868, 54631

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O60500, Q9QZS7

Gene Symbols:
Nphs1

Immunogen:
Nephrin antibody for a 15 amino acid peptide near the carboxy terminus of human Nephrin. The immunogen is within amino acids 1100 - 1150 of Nephrin.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572828

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Antigen:
Beclin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Becn2

Gene Alias:
Bcl-2; BCS2; beclin 1, autophagy related, pseudogene 1; beclin 2; beclin-1 autophagy-related pseudogene 1; Beclin-1-like protein 1; Beclin-2; BECN1L1; BECN1P1; BECN2; Gm104; PFM 2; PFM2; PRDM 5; PRDM5; PRDM5 protein; RGD1563293; similar to Beclin 1 (Coiled-coil myosin-like BCL2-interacting protein)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
441925

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A8MW95

Gene Symbols:
Becn2

Immunogen:
Beclin 2 antibody for a 16 amino acid peptide near the amino terminus of human Beclin 2. The immunogen is within amino acids 30 - 80 of Beclin 2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572829

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Antigen:
WWC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WWC1

Gene Alias:
AA408228; AU017197; BC037006; FLJ10865; FLJ23369; HBeAg-binding protein 3; HBEBP3; HBEBP36; Kiaa0869; KIBRA; Kidney and brain protein; MEMRYQTL; mKIAA0869; PPP1R168; Protein KIBRA; protein phosphatase 1, regulatory subunit 168; protein WWC1; RGD1308329; WW and C2 domain containing 1; WW domain-containing protein 1; WW, C2 and coiled-coil domain containing 1; WWC1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
211652, 23286, 303039

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q5SXA9, Q8IX03

Gene Symbols:
WWC1

Immunogen:
WWC1 antibody for an 18 amino acid peptide near the amino terminus of human WWC1. The immunogen is within amino acids 60 - 110 of WWC1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572830

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Antigen:
GPRASP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GPRASP1

Gene Alias:
2210415K24Rik; 3110031O14Rik; C87852; G protein-coupled receptor associated sorting protein 1; GASP; GASP1; GASP-1; GPRASP1; G-protein coupled receptor-associated sorting protein 1; KIAA0443; Per1 interacting protein; per1-interacting protein; Pips

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
67298, 9737

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q5JY77, Q5U4C1

Gene Symbols:
GPRASP1

Immunogen:
GPRASP1 antibody for a 15 amino acid peptide near the amino terminus of human GPRASP1. The immunogen is within amino acids 260 - 310 of GPRASP1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG