PIPA572832

STEP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572832-Each-of-1 In Stock ₹ 44,705.10

PIPA572832 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

STEP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPN5

Gene Alias

FLJ14427; Neural-specific protein-tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 5; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); protein-tyrosine phosphatase striatum-enriched; protein-tyrosine-phosphatase non-receptor 5; PTN5; PTP STEP; PTPN 5; PTPN5; PTPSTEP; STEP; STEP61; striatal-enriched protein tyrosine phosphatase; striatum-enriched protein-tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19259, 84867

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P54829, P54830

Gene Symbols

PTPN5

Immunogen

PTPN5 antibody for an 18 amino acid peptide near the amino terminus of human PTPN5. The immunogen is within amino acids 180 - 230 of PTPN5.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Reversible phosphorylation of tyrosine residues is a key regulatory mechanism for numerous cellular events such as proliferation, differentiation, gene expression and migration
  • Abnormalities in tyrosine phosphorylation play a role in the pathogenesis of numerous inherited or acquired human diseases from cancer to immune deficiencies
  • There are at least 107 genes coding for PTPs (protein tyrosine phosphatases) in the human genome
  • All known PTPs contain a highly conserved 12 amino acid catalytic domain and are further distinguished on the basis of additional structural motifs
  • The receptor-like PTPs exhibit an extracellular domain, a single transmembrane and one or two intracellular phosphatase domains
  • The nonreceptor cytoplasmic PTPs contain a single phosphatase domain and additional amino acid sequences that are homologous to motifs found in other classes of proteins
  • Protein tyrosine phosphatases PTPN5 (STEP), PTPRR and PTPN7 comprise a family of phosphatases that specifically inactivate MAPKs (mitogen-activated protein kinases)
  • There are multiple forms of STEP in the adult rat brain which show differential enrichment in brain regions implicated in aspects of cognitive, affective, and motor behaviors
  • Some of the STEP isoforms are generated through alternative splicing of a single STEP gene and each has unique intracellular targets and functions.

Compare Similar Items

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Img

Thermo Scientific

PIPA572832

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Antigen:
STEP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN5

Gene Alias:
FLJ14427; Neural-specific protein-tyrosine phosphatase; protein tyrosine phosphatase, non-receptor type 5; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); protein-tyrosine phosphatase striatum-enriched; protein-tyrosine-phosphatase non-receptor 5; PTN5; PTP STEP; PTPN 5; PTPN5; PTPSTEP; STEP; STEP61; striatal-enriched protein tyrosine phosphatase; striatum-enriched protein-tyrosine phosphatase; Tyrosine-protein phosphatase non-receptor type 5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19259, 84867

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P54829, P54830

Gene Symbols:
PTPN5

Immunogen:
PTPN5 antibody for an 18 amino acid peptide near the amino terminus of human PTPN5. The immunogen is within amino acids 180 - 230 of PTPN5.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572833

--


Antigen:
KCNK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kcnk1

Gene Alias:
AI788889; double-pore potassium channel; DPK; HOHO; HOHO1; Inward rectifying potassium channel protein TWIK-1; K2P1; K2p1.1; Kcnk1; kcnk1 {ECO:0000312; KCNO1; Potassium channel K2P1; potassium channel KCNO1; Potassium channel subfamily K member 1; potassium channel TWIK-1; potassium channel, subfamily K, member 1; potassium channel, two pore domain subfamily K, member 1; potassium inwardly-rectifying channel, subfamily K, member 1; potassium two pore domain channel subfamily K member 1; putative potassium channel TWIK; rabKCNK1; RGD:621447}; rTWIK; tandem of P domains in a weak inward rectifying K+ channel 1; Twik; TWIK1; TWIK-1; two-pore potassium channel; Unknown (protein for MGC:142788)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16525, 3775, 59324

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O00180, O08581, Q9Z2T2

Gene Symbols:
Kcnk1

Immunogen:
KCNK1 antibody for a 17 amino acid peptide near the carboxy terminus of human KCNK1. The immunogen is within amino acids 220 - 270 of KCNK1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572834

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Antigen:
SESN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SESN2

Gene Alias:
Hi95; hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; RGD1566319; Ses2; SESN2; SEST2; sestrin 2; sestrin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
230784, 502988, 83667

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P58004, P58043

Gene Symbols:
SESN2

Immunogen:
SESTRIN2 antibody for a 19 amino acid peptide near the center of human SESTRIN2. The immunogen is within amino acids 220 - 270 of SESTRIN2.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572835

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Antigen:
RHOT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RHOT1

Gene Alias:
2210403N23Rik; AA415293; AF244542; AI834919; Arht1; C430039G08Rik; LOW QUALITY PROTEIN: mitochondrial Rho GTPase 1; MGC128572 protein; Miro1; MIRO-1; mitochondrial Rho (MIRO) GTPase 1; mitochondrial Rho GTPase 1; rac-GTP binding protein-like protein; Rac-GTP-binding protein-like protein; ras homolog family member T1; Ras homolog gene family member T1; ras homolog gene family, member T1; Rhot1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
303351, 55288, 59040

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8BG51, Q8IXI2

Gene Symbols:
RHOT1

Immunogen:
RHOT1 antibody for a 15 amino acid peptide near the amino terminus of human RHOT1. The immunogen is within amino acids 40 - 90 of RHOT1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG