PIPA572905

DEDD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572905-Each-of-1 In Stock ₹ 44,705.10

PIPA572905 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DEDD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dedd2

Gene Alias

2410050E11Rik; death effector domain containing 2; death effector domain-containing DNA binding protein 2; death effector domain-containing DNA-binding protein 2; death effector domain-containingDNA binding protein 2; DED-containing protein FLAME-3; DEDD2; DNA-binding death effector domain-containing protein 2; FADD-like anti-apoptotic molecule 3; FLAME3; FLAME-3; PSEC0004

Host Species

Rabbit

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

Conc. Not Determined

Formulation

whole serum with 0.02% sodium azide

Gene Accession No.

Q8WXF8

Gene Symbols

Dedd2

Immunogen

A synthetic peptide corresponding to amino acids 175-193 of human DEDD2/Flame-3 was used as immunogen; GenBank no. gi 19923050 ref NP_579874.1

Regulatory Status

RUO

Gene ID (Entrez)

162989

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • Apoptotic signals are often triggered by cell surface death receptors through protein-protein interactions mediated by conserved domains such as the death effector domain
  • A novel death effector domain (DED)-containing protein, DEDD2, has been recently identified
  • Over-expression of DEDD2 in transfected cells induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas, TRAIL, and FADD
  • More recently, it has been shown that DEDD2 can bind caspase-8 and -10 in addition to FLIP but not FADD
  • Like the related protein DEDD, DEDD2 translocates from the cytosol to the nucleus upon induction of apoptosis, and it has been suggested that DEDD2 may target caspase-8 to the nucleus and that DEDD2 thus plays a critical role in death receptor-induced apoptosis
  • At least two alternatively spliced transcript variants encoding distinct isoforms have been found for DEDD2.

Compare Similar Items

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Img

Thermo Scientific

PIPA572905

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Antigen:
DEDD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dedd2

Gene Alias:
2410050E11Rik; death effector domain containing 2; death effector domain-containing DNA binding protein 2; death effector domain-containing DNA-binding protein 2; death effector domain-containingDNA binding protein 2; DED-containing protein FLAME-3; DEDD2; DNA-binding death effector domain-containing protein 2; FADD-like anti-apoptotic molecule 3; FLAME3; FLAME-3; PSEC0004

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.02% sodium azide

Gene Accession No.:
Q8WXF8

Gene Symbols:
Dedd2

Immunogen:
A synthetic peptide corresponding to amino acids 175-193 of human DEDD2/Flame-3 was used as immunogen; GenBank no. gi 19923050 ref NP_579874.1

Regulatory Status:
RUO

Gene ID (Entrez):
162989

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA572906

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Antigen:
PTPN13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN13

Gene Alias:
AI324989; DKFZp686J1497; FAP-1; Fas-associated protein-tyrosine phosphatase 1; hPTP1E; hPTPE1; PNP1; protein Tyr phosphatase; protein tyrosine phosphatase DPZPTP; Protein tyrosine phosphatase PTP-BL; protein tyrosine phosphatase, non-receptor type 13; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); protein-tyrosine phosphatase 1E; Protein-tyrosine phosphatase PTPL1; protein-tyrosine phosphatase RIP; ptp; Ptp14; PTP1E; PTP36; PTP-BAS; PTP-BL; PTP-E1; PTPL1; PTPLE; PTPN13; Ptpri; RIP; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 13

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q12923

Gene Symbols:
PTPN13

Immunogen:
A recombinant protein corresponding to amino acids 1279 to 1883 of human FAP-1 protein was used as immunogen; GenBank no. NP_542414.1.

Regulatory Status:
RUO

Gene ID (Entrez):
5783

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA572907

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Antigen:
PTPN13

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN13

Gene Alias:
AI324989; DKFZp686J1497; FAP-1; Fas-associated protein-tyrosine phosphatase 1; hPTP1E; hPTPE1; PNP1; protein Tyr phosphatase; protein tyrosine phosphatase DPZPTP; Protein tyrosine phosphatase PTP-BL; protein tyrosine phosphatase, non-receptor type 13; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); protein-tyrosine phosphatase 1E; Protein-tyrosine phosphatase PTPL1; protein-tyrosine phosphatase RIP; ptp; Ptp14; PTP1E; PTP36; PTP-BAS; PTP-BL; PTP-E1; PTPL1; PTPLE; PTPN13; Ptpri; RIP; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 13

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.02% sodium azide

Gene Accession No.:
Q12923

Gene Symbols:
PTPN13

Immunogen:
A synthetic peptide corresponding to amino acids 1760-1775 of human FAP-1; GenBank no. NP_542414.1. This peptide sequence is conserved in multiple isoforms of FAP-1.

Regulatory Status:
RUO

Gene ID (Entrez):
5783

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIPA572908

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Antigen:
NLRC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nlrc4

Gene Alias:
9530011P19Rik; AIFEC; CARD, LRR, and NACHT-containing protein; Card12; caspase recruitment domain family, member 12; caspase recruitment domain-containing protein 12; CLAN; Clan protein; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; ice protease-activating factor; ICE-protease activating factor; ipaf; NLR family CARD domain containing 4; NLR family CARD domain-containing protein 4; NLR family, CARD domain containing 4; NLRC4; NOD-like receptor C4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4; UNQ6189/PRO20215

Host Species:
Rabbit

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q3UP24, Q9NPP4

Gene Symbols:
Nlrc4

Immunogen:
A synthetic peptide corresponding to within amino acis 610 and 660 of Ipaf/Clan/CARD12 was used as immunogen, from genbank sequence NP_067032.3

Regulatory Status:
RUO

Gene ID (Entrez):
268973, 58484

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid