PIPA572962

ATF6 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572962-Each-of-1 In Stock ₹ 44,705.10

PIPA572962 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ATF6

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF6

Gene Alias

9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12915, 1388, 226641, 22926

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.6 mg/mL

Formulation

PBS with 30% glycerol and 0.05% sodium azide

Gene Accession No.

F6VAN0, O35451, P18850, Q99941

Gene Symbols

ATF6, ATF6B

Immunogen

A genomic peptide made to an internal region of the human ATF6 protein (within residues 200-350). [Swiss-Prot P18850]

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • ATF6 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes
  • It binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3')
  • Binding to ERSE requires binding of NF-Y to ERSE
  • ATF6 could also be involved in activation of transcription by the serum response factor
  • ATF6 exists as a homodimer and heterodimer with ATF6 beta
  • The dimer interacts with the nuclear transcription factor Y (NF-Y) trimer through direct binding to NF-Y subunit C (NF-YC)
  • It Interacts also with the transcription factors GTF2I, YY1 and SRF
  • Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus
  • The basic domain of ATF6 functions as a nuclear localization signal and the basic leucine-zipper domain is sufficient for association with the NF-Y trimer and binding to ERSE
  • During the unfolded protein response an approximately 50 kDa fragment containing the cytoplasmic transcription factor domain is released by proteolysis
  • The cleavage seems to be performed sequentially by site-1 and site-2 proteases
  • ATF6 is N-glycosylated, phosphorylated in vitro by MAPK14/P38MAPK and belongs to the bZIP family.

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Thermo Scientific

PIPA572962

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Antigen:
ATF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6

Gene Alias:
9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12915, 1388, 226641, 22926

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.6 mg/mL

Formulation:
PBS with 30% glycerol and 0.05% sodium azide

Gene Accession No.:
F6VAN0, O35451, P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
A genomic peptide made to an internal region of the human ATF6 protein (within residues 200-350). [Swiss-Prot P18850]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA572963

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Antigen:
GLS2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gls2

Gene Alias:
A330074B06Rik; AI195532; breast cell glutaminase; Ga; GLS; GLS2; glutaminase 2; glutaminase 2 (liver, mitochondrial); glutaminase GA; glutaminase I; glutaminase liver isoform, mitochondrial; hLGA; Kiaa4146; L hL L-glutaminase; L hLGA; LGA; L-glutaminase; L-glutamine amidohydrolase; liver mitochondrial glutaminase; phosphate-activated glutaminase; phosphate-dependent glutaminase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
192268, 216456, 27165

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
P28492, Q571F8, Q9UI32

Gene Symbols:
Gls2

Immunogen:
Antibody against a 18 amino acid peptide near the center terminus of human GLS2 (NP_037399).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA572966

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Antigen:
ABCB5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABCB5

Gene Alias:
9230106F14Rik; ABCB5; ABCB5 P-gp; ABCB5alpha; ABCB5beta; ATP binding cassette subfamily B member 5; ATP-binding cassette protein; ATP-binding cassette sub-family B member 5; ATP-binding cassette, subfamily B (MDR/TAP), member 5; ATP-binding cassette, sub-family B (MDR/TAP), member 5; EST422562; P-glycoprotein ABCB5; RGD1566342

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
340273, 77706

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.05% sodium azide

Gene Accession No.:
B5X0E4, Q2M3G0

Gene Symbols:
ABCB5

Immunogen:
A synthetic peptide made to an internal portion of the human ABCB5 protein (between residues 150-200) [UniProt Q2M3G0]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA572967

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Antigen:
GLI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLI1

Gene Alias:
AV235269; GLI; GLI family zinc finger 1; Gli1; GLI-Kruppel family member GLI1; Glioma-associated oncogene; glioma-associated oncogene 1; glioma-associated oncogene homolog; glioma-associated oncogene homolog 1 (zinc finger protein); oncogene GLI; Zfp5; Zfp-5; zinc finger protein 5; zinc finger protein GLI1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14632, 2735

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), In Situ Hybridization (ISH), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P08151, P47806

Gene Symbols:
GLI1

Immunogen:
A synthetic peptide made to an internal portion of the human Gli1 protein (between residues 150-200) [UniProt P08151]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG