PIPA572973

PIEZO1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA572973-Each-of-1 In Stock ₹ 44,277.30

PIPA572973 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

PIEZO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Piezo1

Gene Alias

9630020g22; DHS; Fam38a; family with sequence similarity 38, member A; KIAA0233; LMPH3; Membrane protein induced by beta-amyloid treatment; Mib; mKIAA0233; piezo type mechanosensitive ion channel component 1; Piezo1; piezo-type mechanosensitive ion channel component 1; Protein FAM38A; protein PIEZO1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100733448, 234839, 9780

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

E2JF22, Q92508

Gene Symbols

Piezo1

Immunogen

A synthetic peptide made to an internal portion of the human PIEZO1 protein (between residues 950-1000) [UniProt Q92508]

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Guinea Pig, Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Piezo1 is a pore-forming subunit of a mechanosensitive non-specific cation channel, and generates currents characterized by a linear current-voltage relationship that are sensitive to ruthenium red and gadolinium
  • Structurally, Piezo1 contains 36 transmembrane domains and functions as a homotetramer
  • Piezo1 plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling
  • In the kidney, Piezo1 may contribute to the detection of intraluminal pressure changes and to urine flow sensing
  • Piezo1 acts as shear-stress sensor that promotes endothelial cell organization and alignment in the direction of blood flow through calpain activation and plays a key role in blood vessel formation and vascular structure in both development and adult physiology
  • The protein encoded by the Piezo1 gene is a mechanically-activated ion channel that links mechanical forces to biological signals
  • Defects in this gene have been associated with dehydrated hereditary stomatocytosis
  • Diseases associated with PIEZO1 include Dehydrated Hereditary Stomatocytosis with/without Pseudohyperkalemia And/Or Perinatal Edema and Lymphedema.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA572973

--


Antigen:
PIEZO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Piezo1

Gene Alias:
9630020g22; DHS; Fam38a; family with sequence similarity 38, member A; KIAA0233; LMPH3; Membrane protein induced by beta-amyloid treatment; Mib; mKIAA0233; piezo type mechanosensitive ion channel component 1; Piezo1; piezo-type mechanosensitive ion channel component 1; Protein FAM38A; protein PIEZO1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100733448, 234839, 9780

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
E2JF22, Q92508

Gene Symbols:
Piezo1

Immunogen:
A synthetic peptide made to an internal portion of the human PIEZO1 protein (between residues 950-1000) [UniProt Q92508]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Guinea Pig, Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572974

--


Antigen:
PIEZO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Piezo1

Gene Alias:
9630020g22; DHS; Fam38a; family with sequence similarity 38, member A; KIAA0233; LMPH3; Membrane protein induced by beta-amyloid treatment; Mib; mKIAA0233; piezo type mechanosensitive ion channel component 1; Piezo1; piezo-type mechanosensitive ion channel component 1; Protein FAM38A; protein PIEZO1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
234839, 9780

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
E2JF22, Q92508

Gene Symbols:
Piezo1

Immunogen:
A synthetic peptide made to an internal portion of the human PIEZO1 protein (between residues 1300-1350) [UniProt Q92508]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA572976

--


Antigen:
PIEZO2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIEZO2

Gene Alias:
5930434P17; 9030411M15Rik; 9430028L06Rik; C18orf30; C18orf58; DA3; DA5; Fam38b; FAM38B2; family with sequence similarity 38, member A pseudogene; family with sequence similarity 38, member B; family with sequence similarity 38, member B2; HsT748; HsT771; LOW QUALITY PROTEIN: piezo-type mechanosensitive ion channel component 2; MWKS; piezo type mechanosensitive ion channel component 2; Piezo2; piezo-type mechanosensitive ion channel component 1 pseudogene; piezo-type mechanosensitive ion channel component 2; piezo-type mechanosensitive ion channel component 2 pseudogene; Protein FAM38B; protein PIEZO2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100734606, 307380, 63895, 667742

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8CD54, Q9H5I5

Gene Symbols:
PIEZO2

Immunogen:
A synthetic peptide made to an internal portion of the human PIEZO2 protein (between residues 1600-1650) [UniProt Q9H5I5]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Guinea Pig, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA572977

--


Antigen:
NLRC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nlrc4

Gene Alias:
9530011P19Rik; AIFEC; CARD, LRR, and NACHT-containing protein; Card12; caspase recruitment domain family, member 12; caspase recruitment domain-containing protein 12; CLAN; Clan protein; CLAN1; CLANA; CLANB; CLANC; CLAND; CLR2.1; FCAS4; ice protease-activating factor; ICE-protease activating factor; ipaf; NLR family CARD domain containing 4; NLR family CARD domain-containing protein 4; NLR family, CARD domain containing 4; NLRC4; NOD-like receptor C4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4; UNQ6189/PRO20215

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
268973, 58484

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.13 mg/mL

Formulation:
PBS with 30% glycerol and 0.05% sodium azide

Gene Accession No.:
Q3UP24, Q9NPP4

Gene Symbols:
Nlrc4

Immunogen:
A synthetic peptide made to an internal portion of the human CARD12 protein (between residues 600-700) [UniProt Q9NPP4]

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG