PIPA572986
SETX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA572986-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA572986 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SETX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SETX
Gene Alias
A130090N03; A930037J23Rik; Als4; amyotrophic lateral sclerosis 4 homolog; amyotrophic lateral sclerosis 4 protein; Amyotrophic lateral sclerosis 4 protein homolog; AOA2; AW060766; bA479K20.2; DEAxQ-box helicase; KIAA0625; mKIAA0625; Probable helicase senataxin; RGD1565575; SCAR1; Sen1; SEN1 homolog; senataxin; Setx; tRNA splicing endonuclease regulator 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23064, 269254
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 30% glycerol and 0.05% sodium azide
Gene Accession No.
A2AKX3, Q7Z333
Gene Symbols
SETX
Immunogen
A genomic peptide made to an internal portion of the human Senataxin protein (between residues 600-750) [UniProt Q7Z333]
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- Probable RNA/DNA helicase involved in diverse aspects of RNA metabolism and genomic integrity
- Plays a role in transcription regulation by its ability to modulate RNA Polymerase II (Pol II) binding to chromatin and through its interaction with proteins involved in transcription (PubMed:19515850, PubMed:21700224)
- Contributes to the mRNA splicing efficiency and splice site selection (PubMed:19515850)
- Required for the resolution of R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site, allowing XRN2 recruitment and XRN2-mediated degradation of the downstream cleaved RNA and hence efficient RNA polymerase II (RNAp II) transcription termination (PubMed:19515850, PubMed:21700224, PubMed:26700805)
- Required for the 3' transcriptional termination of PER1 and CRY2, thus playing an important role in the circadian rhythm regulation
- Involved in DNA double-strand breaks damage response generated by oxidative stress (PubMed:17562789)
- In association with RRP45, targets the RNA exosome complex to sites of transcription-induced DNA damage (PubMed:24105744)
- Plays a role in the development and maturation of germ cells: essential for male meiosis, acting at the interface of transcription and meiotic recombination, and in the process of gene silencing during meiotic sex chromosome inactivation (MSCI)
- May be involved in telomeric stability through the regulation of telomere repeat-containing RNA (TERRA) transcription (PubMed:21112256)
- Plays a role in neurite outgrowth in hippocampal cells through FGF8-activated signaling pathways
- Inhibits retinoic acid-induced apoptosis (PubMed:21576111).
Compare Similar Items
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Antigen: SETX
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SETX
Gene Alias: A130090N03; A930037J23Rik; Als4; amyotrophic lateral sclerosis 4 homolog; amyotrophic lateral sclerosis 4 protein; Amyotrophic lateral sclerosis 4 protein homolog; AOA2; AW060766; bA479K20.2; DEAxQ-box helicase; KIAA0625; mKIAA0625; Probable helicase senataxin; RGD1565575; SCAR1; Sen1; SEN1 homolog; senataxin; Setx; tRNA splicing endonuclease regulator 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23064, 269254
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 30% glycerol and 0.05% sodium azide
Gene Accession No.: A2AKX3, Q7Z333
Gene Symbols: SETX
Immunogen: A genomic peptide made to an internal portion of the human Senataxin protein (between residues 600-750) [UniProt Q7Z333]
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SETX
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SETX
Gene Alias:
A130090N03; A930037J23Rik; Als4; amyotrophic lateral sclerosis 4 homolog; amyotrophic lateral sclerosis 4 protein; Amyotrophic lateral sclerosis 4 protein homolog; AOA2; AW060766; bA479K20.2; DEAxQ-box helicase; KIAA0625; mKIAA0625; Probable helicase senataxin; RGD1565575; SCAR1; Sen1; SEN1 homolog; senataxin; Setx; tRNA splicing endonuclease regulator 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23064, 269254
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 30% glycerol and 0.05% sodium azide
Gene Accession No.:
A2AKX3, Q7Z333
Gene Symbols:
SETX
Immunogen:
A genomic peptide made to an internal portion of the human Senataxin protein (between residues 600-750) [UniProt Q7Z333]
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PIF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PIF1
Gene Alias: 4631410M14; AI449441; ATP-dependent DNA helicase PIF1; ATP-dependent DNA helicase PIF1 {ECO:0000255; C15orf20; DNA helicase-like protein; DNA repair and recombination helicase PIF1; DNA repair and recombination helicase PIF1 {ECO:0000255; HAMAP-Rule:MF_03176}; petite integration frequency 1; PIF; Pif1; PIF1 5'-to-3' DNA helicase; PIF1 5'-to-3' DNA helicase homolog; PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae); PIF1 homolog; Pif1/Rrm3 DNA helicase-like protein; Pif1/Rrm3 DNA-helicase-like protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 208084
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.16 mg/mL
Formulation: PBS with 30% glycerol and 0.05% sodium azide
Gene Accession No.: Q80SX8
Gene Symbols: PIF1
Immunogen: A synthetic peptide made to an internal portion of the human PIF1 protein (between residues 400-500) [UniProt Q9H611]
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PIF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PIF1
Gene Alias:
4631410M14; AI449441; ATP-dependent DNA helicase PIF1; ATP-dependent DNA helicase PIF1 {ECO:0000255; C15orf20; DNA helicase-like protein; DNA repair and recombination helicase PIF1; DNA repair and recombination helicase PIF1 {ECO:0000255; HAMAP-Rule:MF_03176}; petite integration frequency 1; PIF; Pif1; PIF1 5'-to-3' DNA helicase; PIF1 5'-to-3' DNA helicase homolog; PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae); PIF1 homolog; Pif1/Rrm3 DNA helicase-like protein; Pif1/Rrm3 DNA-helicase-like protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
208084
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.16 mg/mL
Formulation:
PBS with 30% glycerol and 0.05% sodium azide
Gene Accession No.:
Q80SX8
Gene Symbols:
PIF1
Immunogen:
A synthetic peptide made to an internal portion of the human PIF1 protein (between residues 400-500) [UniProt Q9H611]
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: IIGP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Iigp1
Gene Alias: 2900074L10Rik; AI046432; AW111922; Ifgga1; Iigp; Iigp1; interferon inducible GTPase 1; interferon-gamma-inducible GTPase Ifgga1 protein; interferon-inducible GTPase 1; Irga6
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 60440
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.: Q9QZ85
Gene Symbols: Iigp1
Immunogen: A portion of amino acids 325-375 of mouse Iigp1 was used as the immunogen for this antibody.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IIGP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Iigp1
Gene Alias:
2900074L10Rik; AI046432; AW111922; Ifgga1; Iigp; Iigp1; interferon inducible GTPase 1; interferon-gamma-inducible GTPase Ifgga1 protein; interferon-inducible GTPase 1; Irga6
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
60440
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.:
Q9QZ85
Gene Symbols:
Iigp1
Immunogen:
A portion of amino acids 325-375 of mouse Iigp1 was used as the immunogen for this antibody.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HMGN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HMGN1
Gene Alias: FLJ27265; FLJ31471; high mobility group nucleosomal binding domain 1; high mobility group nucleosome binding domain 1; high mobility group nucleosome-binding domain-containing protein 1; high mobility group protein 14; high-mobility group (nonhistone chromosomal) protein 14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; high-mobility group nucleosome-binding domain-containing protein 1; HMG 14; Hmg14; HMG-14; HMGN 1; Hmgn1; MGC104230; MGC117425; Non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 100625838, 108175971, 3150, 608119, 614915
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.: P02316, P05114
Gene Symbols: HMGN1
Immunogen: A portion of amino acids 1-50 from human HMG14 was used as the immunogen for this antibody.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Human, Non-human Primate, Porcine, Rabbit
Product Type: Antibody
Isotype: IgG
Antigen:
HMGN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HMGN1
Gene Alias:
FLJ27265; FLJ31471; high mobility group nucleosomal binding domain 1; high mobility group nucleosome binding domain 1; high mobility group nucleosome-binding domain-containing protein 1; high mobility group protein 14; high-mobility group (nonhistone chromosomal) protein 14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; high-mobility group nucleosome-binding domain-containing protein 1; HMG 14; Hmg14; HMG-14; HMGN 1; Hmgn1; MGC104230; MGC117425; Non-histone chromosomal protein HMG-14; nonhistone chromosomal protein HMG-14
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
100625838, 108175971, 3150, 608119, 614915
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.:
P02316, P05114
Gene Symbols:
HMGN1
Immunogen:
A portion of amino acids 1-50 from human HMG14 was used as the immunogen for this antibody.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Human, Non-human Primate, Porcine, Rabbit
Product Type:
Antibody
Isotype:
IgG