PIPA575198
MTCO1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA575198-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA575198 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MTCO1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
mt-Co1
Gene Alias
Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17708, 26195, 4512
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P00395, P00397, P05503
Gene Symbols
mt-Co1
Immunogen
Synthetic peptide corresponding to amino acids 433-445 of Mouse MTCOI.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
- Cytochrome c oxidase subunit I (CO1 or MTCO1) is 1 of 3 mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV
- Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation
- It is composed of 13 polypeptides
- Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded
- The cytochrome c oxidase family of enzymes have 4 redox centers, 2 hemes and 2 copper centers
- In mitochondrial Complex IV, the 2 hemes are a and a3 and the 2 coppers are CuA and CuB
- The 2 hemes and CuB are bound to subunit I
- Acin-Perez et al
- (2003) identified a cell line containing single and double missense mutations in the cytochrome c oxidase (COX) subunit I gene of mouse mitochondrial DNA
- And they hypothesized that deleterious mutations can arise and become predominant; cultured cells can maintain several mtDNA haplotypes at stable frequencies; the respiratory chain has little spare COX capacity; and that the size of a cavity in the vicinity of val421 in MTCO1I of animal COX may affect the function of the enzyme.
Compare Similar Items
Show Difference
Antigen: MTCO1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: mt-Co1
Gene Alias: Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17708, 26195, 4512
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P00395, P00397, P05503
Gene Symbols: mt-Co1
Immunogen: Synthetic peptide corresponding to amino acids 433-445 of Mouse MTCOI.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MTCO1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
mt-Co1
Gene Alias:
Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17708, 26195, 4512
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P00395, P00397, P05503
Gene Symbols:
mt-Co1
Immunogen:
Synthetic peptide corresponding to amino acids 433-445 of Mouse MTCOI.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MTCO2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MT-CO2
Gene Alias: ACI60_gp02; Co2; COII; COX2; COXII; cyclooxygenase; cytchrome c oxidase sububnit 2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; mitochondrially encoded cytochrome c oxidase II; Mtco2; MT-CO2; OXI1; OXII; Q0250
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17709, 4513
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P00403, P00405, P35354
Gene Symbols: COX2, MT-CO2
Immunogen: Synthetic peptide corresponding to amino acids 49-63 of Mouse MTCO2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MTCO2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MT-CO2
Gene Alias:
ACI60_gp02; Co2; COII; COX2; COXII; cyclooxygenase; cytchrome c oxidase sububnit 2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; mitochondrially encoded cytochrome c oxidase II; Mtco2; MT-CO2; OXI1; OXII; Q0250
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17709, 4513
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P00403, P00405, P35354
Gene Symbols:
COX2, MT-CO2
Immunogen:
Synthetic peptide corresponding to amino acids 49-63 of Mouse MTCO2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: COX3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MT-CO3
Gene Alias: ACI60_gp01; Co3; Coiii; COX3; COXIII; cytchrome c oxidase sububnit 3; Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3; cytochrome c oxidase subunit III; mitochondrially encoded cytochrome c oxidase III; Mtco3; mt-Co3; OXI2; Q0275
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 139542, 17710, 4514
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P00414, P00416
Gene Symbols: COX3, MT-CO3
Immunogen: Synthetic peptide corresponding to amino acids 57-71 of Mouse COX3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
COX3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MT-CO3
Gene Alias:
ACI60_gp01; Co3; Coiii; COX3; COXIII; cytchrome c oxidase sububnit 3; Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3; cytochrome c oxidase subunit III; mitochondrially encoded cytochrome c oxidase III; Mtco3; mt-Co3; OXI2; Q0275
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
139542, 17710, 4514
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P00414, P00416
Gene Symbols:
COX3, MT-CO3
Immunogen:
Synthetic peptide corresponding to amino acids 57-71 of Mouse COX3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: PMP22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PMP22
Gene Alias: 22kDa; Cd25; CMT1A; CMT1E; DSS; GAS3; GAS-3; Growth arrest-specific protein 3; HMSNIA; HNPP; peripheral myelin; peripheral myelin protein 22; peripheral myelin protein 22 kDa; PMP22; PMP-22; Protein CD25; SAG; schwann cell membrane glycoprotein; Sp110; SR13 myelin protein; Tr; trembler
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18858, 5376
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P16646, Q01453
Gene Symbols: PMP22
Immunogen: Synthetic peptide corresponding to amino acids 120-170 of Human PMP22.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PMP22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PMP22
Gene Alias:
22kDa; Cd25; CMT1A; CMT1E; DSS; GAS3; GAS-3; Growth arrest-specific protein 3; HMSNIA; HNPP; peripheral myelin; peripheral myelin protein 22; peripheral myelin protein 22 kDa; PMP22; PMP-22; Protein CD25; SAG; schwann cell membrane glycoprotein; Sp110; SR13 myelin protein; Tr; trembler
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18858, 5376
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P16646, Q01453
Gene Symbols:
PMP22
Immunogen:
Synthetic peptide corresponding to amino acids 120-170 of Human PMP22.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG