PIPA575235
MLLT10 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA575235-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA575235 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MLLT10
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MLLT10
Gene Alias
Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17354, 361285, 8028
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O54826, P55197
Gene Symbols
MLLT10
Immunogen
Synthetic peptide corresponding to amino acids 200-250 of Human MLLT10.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
- Translocations affecting chromosome 11q23 involve many partner chromosome regions and occur in various leukemias
- The 11q23 gene involved in the translocations is MLL
- MLLT10 is the partner gene to MLL1 involved in t(10;11)(p12;q23) translocations
- In an analysis of two leukemia patients, the in t(10;11)(p12;q23) translocation fuses MLL1, a SET domain containg histone methyltransferase, to the MLLT10 gene
- The MLLT10 gene encodes a predicted 1,027-amino acid protein containing an N-terminal zinc finger and a C-terminal leucine zipper domain
- The MLLT10 gene is one of the few MLL partner genes to be independently rearranged with a third gene in leukemia, the CALM gene in the t(10;11)(p12;q14) translocation
- Chimeric fusion proteins MLL/AF10 and CALM/AF10 consistently retain the leucine zipper motif of MLLT10
- The leucine zipper interacts with GAS41, a protein previously identified as the product of an amplified gene in a glioblastoma
- GAS41 interacts with integrase interactor-1 (INI1), a component of the SWI/SNF complex, which acts to remodel chromatin and to modulate transcription
- Retention of the leucine zipper in the MLL and CALM fusions suggested that a key feature of these chimeric proteins may be their ability to interfere in normal gene regulation through interaction with the adenosine triphosphate-dependent chromatin remodeling complexes.
Compare Similar Items
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Antigen: MLLT10
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MLLT10
Gene Alias: Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17354, 361285, 8028
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: O54826, P55197
Gene Symbols: MLLT10
Immunogen: Synthetic peptide corresponding to amino acids 200-250 of Human MLLT10.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MLLT10
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MLLT10
Gene Alias:
Af10; af-10; ALL1-fused gene from chromosome 10 protein; B130021D15Rik; D630001B22Rik; DKFZp686E10210; MGC75086; mKIAA4140; MLLT10; myeloid/lymphoid or mixed lineage-leukemia translocation to 10 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia translocated to, 10; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10; protein AF-10; translocated to, 10; type I AF10 protein; type III AF10 protein; type IV AF10 protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17354, 361285, 8028
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
O54826, P55197
Gene Symbols:
MLLT10
Immunogen:
Synthetic peptide corresponding to amino acids 200-250 of Human MLLT10.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SCAND1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SCAND1
Gene Alias: 2310003H23Rik; DIPP; DIPP1; Leap1; leucine-rich-domain inter-acting protein 1; peroxisome proliferative activated receptor, gamma, coactivator 2; PGC-2; Ppargc2; RAZ1; SCAN domain containing 1; SCAN domain-containing 1; SCAN domain-containing protein 1; Scand1; SCAN-related protein RAZ1; SDP1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19018, 362252, 51282
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P57086
Gene Symbols: SCAND1
Immunogen: Synthetic peptide corresponding to amino acids 50-100 of Human SCAND1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SCAND1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SCAND1
Gene Alias:
2310003H23Rik; DIPP; DIPP1; Leap1; leucine-rich-domain inter-acting protein 1; peroxisome proliferative activated receptor, gamma, coactivator 2; PGC-2; Ppargc2; RAZ1; SCAN domain containing 1; SCAN domain-containing 1; SCAN domain-containing protein 1; Scand1; SCAN-related protein RAZ1; SDP1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19018, 362252, 51282
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P57086
Gene Symbols:
SCAND1
Immunogen:
Synthetic peptide corresponding to amino acids 50-100 of Human SCAND1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: LMO4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LMO4
Gene Alias: A730077C12Rik; Breast tumor autoantigen; Crp3; ethanol induced 4; Etohi4; LIM domain only 4; LIM domain only protein 4; LIM domain transcription factor LMO4; LIM-only 4 protein; LMO4; LMO-4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16911, 362051, 8543
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P61968, P61969
Gene Symbols: LMO4
Immunogen: Synthetic peptide corresponding to amino acids 107-150 of Human LMO4.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LMO4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LMO4
Gene Alias:
A730077C12Rik; Breast tumor autoantigen; Crp3; ethanol induced 4; Etohi4; LIM domain only 4; LIM domain only protein 4; LIM domain transcription factor LMO4; LIM-only 4 protein; LMO4; LMO-4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16911, 362051, 8543
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P61968, P61969
Gene Symbols:
LMO4
Immunogen:
Synthetic peptide corresponding to amino acids 107-150 of Human LMO4.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MEF2B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MEF2B
Gene Alias: 2310045N01Rik; AI451606; BLOC-1-related complex subunit 8; Borcs8; BORCS8-MEF2B; BORCS8-MEF2B readthrough; LOC729991-MEF2B; LOC729991-MEF2B readthrough; MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B); MEF2B; MEF2B neighbor gene protein homolog; Mef2bnb; MEF2BNB-MEF2B; MEF2BNB-MEF2B readthrough; myocyte enhancer factor 2B; myocyte-specific enhancer factor 2B; protein MEF2BNB; RIKEN cDNA 2310045N01 gene; RSRFR2; Serum response factor-like protein 2; XMEF2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100271849, 17259, 498607
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide; pH 7.2
Gene Accession No.: O55087, Q02080
Gene Symbols: MEF2B
Immunogen: Synthetic peptide corresponding to amino acids 80-120 of Human MEF2B.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MEF2B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MEF2B
Gene Alias:
2310045N01Rik; AI451606; BLOC-1-related complex subunit 8; Borcs8; BORCS8-MEF2B; BORCS8-MEF2B readthrough; LOC729991-MEF2B; LOC729991-MEF2B readthrough; MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B); MEF2B; MEF2B neighbor gene protein homolog; Mef2bnb; MEF2BNB-MEF2B; MEF2BNB-MEF2B readthrough; myocyte enhancer factor 2B; myocyte-specific enhancer factor 2B; protein MEF2BNB; RIKEN cDNA 2310045N01 gene; RSRFR2; Serum response factor-like protein 2; XMEF2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100271849, 17259, 498607
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide; pH 7.2
Gene Accession No.:
O55087, Q02080
Gene Symbols:
MEF2B
Immunogen:
Synthetic peptide corresponding to amino acids 80-120 of Human MEF2B.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG