PIPA575316

MUTYH Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA575316-Each-of-1 In Stock ₹ 44,705.10

PIPA575316 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MUTYH

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MUTYH

Gene Alias

5730495A01Rik; A/G-specific adenine DNA glycosylase; adenine DNA glycosylase; adenine-DNA glycosylase; hMYH; MGC4416; mMYH; mutY DNA glycosylase; mutY homolog; mutY homolog (E. coli); mutY homolog alpha; Mutyh; Mutyha; Mutyhalpha; Mutyhb; Mutyhbeta; Mutyhc; mutY-like protein; Myh; OTTHUMP00000009098; OTTHUMP00000009102; rMYH; RP4-534D1.2; the full-length form type A, 5' region

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

170841, 4595, 70603

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8R5G2, Q99P21, Q9UIF7

Gene Symbols

MUTYH

Immunogen

Synthetic peptide corresponding to amino acids 142-190 of Human MUTYH.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • MYH (mutY homolog (E
  • coli )) is a DNA glycosylase mismatch repair enzyme that in conjunction with mutM (OGG1), cleaves adenine residues paired with either oxidized (8-hydroxyguanines) or non-modified guanines in order to correct A/G and A/C mismatches
  • Repair of most modified and mispaired bases in the genome is initiated by DNA glycosylases, which bind and cleave N-glycosyl bonds to initiate base excision repair
  • MYH is crucial for the avoidance of mutations resulting from oxidative DNA damage
  • Multiple N-terminal splice variants of MYH exist in mammalian cells
  • Increasing levels of MYH in A549 cells exposed to oxygen and infrared radiation leads to improvements in cell survival
  • Biallelic MYH germ-line mutations predispose humans to colorectal adenomas and carcinomas
  • MYH is abundant in neurons where mitochondrial genomes exposed to reactive oxygen species (ROS) that damage DNA must maintain integrity over the entire mammalian life span.

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Img

Thermo Scientific

PIPA575316

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Antigen:
MUTYH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MUTYH

Gene Alias:
5730495A01Rik; A/G-specific adenine DNA glycosylase; adenine DNA glycosylase; adenine-DNA glycosylase; hMYH; MGC4416; mMYH; mutY DNA glycosylase; mutY homolog; mutY homolog (E. coli); mutY homolog alpha; Mutyh; Mutyha; Mutyhalpha; Mutyhb; Mutyhbeta; Mutyhc; mutY-like protein; Myh; OTTHUMP00000009098; OTTHUMP00000009102; rMYH; RP4-534D1.2; the full-length form type A, 5' region

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170841, 4595, 70603

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q8R5G2, Q99P21, Q9UIF7

Gene Symbols:
MUTYH

Immunogen:
Synthetic peptide corresponding to amino acids 142-190 of Human MUTYH.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575317

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Antigen:
RAD51B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rad51b

Gene Alias:
AI553500; DNA repair protein RAD51 homolog 2; hREC2; MGC34245; mREC2; R51H2; R51H2REC2hREC2; RAD51 homolog B; RAD51 paralog B; Rad51B; Rad51l1; RAD51-like 1; RAD51-like protein 1; REC2; RecA-like protein; recombination repair protein; RGD1560681

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19363, 5890

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O15315, O35719

Gene Symbols:
Rad51b

Immunogen:
Synthetic peptide corresponding to amino acids 201-250 of Human Rad51B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575318

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Antigen:
CLK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLK1

Gene Alias:
CDC like kinase 1; CDC28/CDC2-like kinase; CDC-like kinase 1; CLK; CLK/STY; CLK1; Dual specificity protein kinase CLK1; Protein kinase CLK1; protein kinase STY; protein tyrosine kinase STY; Sty

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1195, 12747

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P22518, P49759

Gene Symbols:
CLK1

Immunogen:
Synthetic peptide corresponding to amino acids 100-150 of Human CLK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575320

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Antigen:
GAS6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAS6

Gene Alias:
AXL receptor tyrosine kinase ligand; AXL stimulatory factor; AXLLG; AXSF; GAS 6; GAS6; GAS-6; GPF; growth arrest specific 6; growth arrest-specific 6; growth arrest-specific protein 6; growth-potentiating factor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14456, 2621, 58935

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q14393, Q61592, Q63772

Gene Symbols:
GAS6

Immunogen:
Synthetic peptide corresponding to amino acids 278-328 of Human Gas6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG