PIPA575694

Supt4h1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575694-Each-of-1 In Stock ₹ 44,705.10

PIPA575694 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Supt4h1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SUPT4H1

Gene Alias

AL022777; DRB sensitivity-inducing factor 14 kDa subunit; DRB sensitivity-inducing factor small subunit; DRB sensitivity-inducing factor small subunit 1; DSIF p14; DSIF small subunit; DSIF small subunit 1; hSPT4; small hSpt4 subunit; SPT4; SPT4 homolog, DSIF elongation factor subunit; SPT4H; suppressor of Ty 4 homolog 1; suppressor of Ty 4 homolog 1 (S. cerevisiae); suppressor of Ty 4 homolog 2; suppressor of Ty 4A; Supt4a; Supt4h; Supt4h1; Supt4h1a; Supt4h2; transcription elongation factor SPT4; Transcription elongation factor SPT4 1; transcription elongation factor SPT4-A; zgc:92824; zgc:92824 protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20922, 287608, 6827

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P63271, P63272

Gene Symbols

Supt4a, SUPT4H1

Immunogen

Synthetic peptide corresponding to residues in Human SUPT4H1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II
  • DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A
  • DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter
  • Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex
  • DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II
  • TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme
  • Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites
  • DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat
  • DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.

Compare Similar Items

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Img

Thermo Scientific

PIPA575694

--


Antigen:
Supt4h1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SUPT4H1

Gene Alias:
AL022777; DRB sensitivity-inducing factor 14 kDa subunit; DRB sensitivity-inducing factor small subunit; DRB sensitivity-inducing factor small subunit 1; DSIF p14; DSIF small subunit; DSIF small subunit 1; hSPT4; small hSpt4 subunit; SPT4; SPT4 homolog, DSIF elongation factor subunit; SPT4H; suppressor of Ty 4 homolog 1; suppressor of Ty 4 homolog 1 (S. cerevisiae); suppressor of Ty 4 homolog 2; suppressor of Ty 4A; Supt4a; Supt4h; Supt4h1; Supt4h1a; Supt4h2; transcription elongation factor SPT4; Transcription elongation factor SPT4 1; transcription elongation factor SPT4-A; zgc:92824; zgc:92824 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20922, 287608, 6827

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P63271, P63272

Gene Symbols:
Supt4a, SUPT4H1

Immunogen:
Synthetic peptide corresponding to residues in Human SUPT4H1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575695

--


Antigen:
MED11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MED11

Gene Alias:
1110030J09Rik; AI465144; AW545069; HSPC296; MED11; Mediator complex subunit 11; mediator of RNA polymerase II transcription subunit 11; mediator of RNA polymerase II transcription, subunit 11 homolog; RGD1563202

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287456, 400569, 66172

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9D8C6, Q9P086

Gene Symbols:
MED11

Immunogen:
Synthetic peptide corresponding to residues in Human MED11.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575697

--


Antigen:
TCEAL8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TCEAL8

Gene Alias:
3930402F23Rik; MGC45400; TCEAL8; TCEA-like protein 8; transcription elongation factor A (SII)-like 8; transcription elongation factor A like 8; transcription elongation factor A protein-like 8; Transcription elongation factor S-II protein-like 8; up-regulated in nephrectomized rat kidney #1; UR-NR#1; WEX3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
367909, 66684, 90843

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6I7R5, Q8IYN2, Q9CZY2

Gene Symbols:
TCEAL8

Immunogen:
Synthetic peptide corresponding to residues in Human TCEAL8.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575699

--


Antigen:
APOC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOC4

Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; Acl; AD1; AICD-50; AICD-57; AICD-59; Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid protein; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; APOC4; Apo-CIV; apoC-IV; Apolipoprotein; apolipoprotein C2 linked; apolipoprotein C2-linked; Apolipoprotein C4; apolipoprotein CIV; Apolipoprotein C-IV; apolipoprotein E-linked; APP; APPI; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; CVAP; ECL; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-termi

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11425, 346

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P55056, Q61268

Gene Symbols:
APOC4

Immunogen:
Synthetic peptide corresponding to residues in Human APOC4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG