PIPA575791

UNC5A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575791-Each-of-1 In Stock ₹ 44,705.10

PIPA575791 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

UNC5A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Unc5a

Gene Alias

Kiaa1976; mKIAA1976; netrin receptor UNC5A; netrin receptor Unc5h1; protein unc-5 homolog 1; Protein unc-5 homolog A; transmembrane receptor Unc5H1; unc5 (C.elegans homolog) a; unc5 homolog 1; unc-5 homolog 1; unc-5 homolog A; unc-5 homolog A (C. elegans); unc-5 netrin receptor A; UNC5A; Unc5h1; UNC5H1FLJ16449

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

107448, 60629, 90249

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O08721, Q6ZN44, Q8K1S4

Gene Symbols

Unc5a

Immunogen

Synthetic peptide corresponding to residues in Human UNC5A

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA575786

--

Img

Thermo Scientific

PIPA575749

--

Img

Thermo Scientific

PIPA575673

--

Img

Thermo Scientific

PIPA575823

--

Img

Thermo Scientific

PIPA575748

--

Img

Thermo Scientific

PIPA575609

--

Img

Thermo Scientific

PIPA575904

--

Img

Thermo Scientific

PIPA575630

--

Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells
  • Additionally, when cleaved by a caspase to produce an intracellular fragment containing a death domain, UNC5H receptors induce apoptosis
  • This activity is blocked by the binding of netrin-1
  • In the absence of netrin-1, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion, but mutation of these receptors provides a potential mechanism for tumorigenicity
  • The expression of UNC5H receptors is downregulated in multiple carcinomas, including colorectal, breast, ovary, uterus, stomach, lung and kidney cancers
  • UNC5H1, also known as UNC5HA (unc-5 homolog A), is a member of the UNC5H family of proteins and is localized to the cell membrane
  • Three isoforms of UNC5H1 exist due to alternative splicing events.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA575791

--


Antigen:
UNC5A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Unc5a

Gene Alias:
Kiaa1976; mKIAA1976; netrin receptor UNC5A; netrin receptor Unc5h1; protein unc-5 homolog 1; Protein unc-5 homolog A; transmembrane receptor Unc5H1; unc5 (C.elegans homolog) a; unc5 homolog 1; unc-5 homolog 1; unc-5 homolog A; unc-5 homolog A (C. elegans); unc-5 netrin receptor A; UNC5A; Unc5h1; UNC5H1FLJ16449

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107448, 60629, 90249

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O08721, Q6ZN44, Q8K1S4

Gene Symbols:
Unc5a

Immunogen:
Synthetic peptide corresponding to residues in Human UNC5A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575792

--


Antigen:
A20A3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ANKRD20A3

Gene Alias:
ANKRD20A3; ankyrin repeat domain 20 family member A3; ankyrin repeat domain 20 family, member A3; ankyrin repeat domain 20A-related; ankyrin repeat domain-containing protein 20A3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
441425

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5VUR7

Gene Symbols:
ANKRD20A3

Immunogen:
Synthetic peptide corresponding to residues in Human A20A3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575795

--


Antigen:
A20A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ANKRD20A1

Gene Alias:
ANKRD20A; ANKRD20A1; ankyrin repeat domain 20 family member A1; ankyrin repeat domain 20 family, member A1; ankyrin repeat domain 20A; ankyrin repeat domain-containing protein 20A1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84210

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5TYW2

Gene Symbols:
ANKRD20A1

Immunogen:
Synthetic peptide corresponding to residues in Human A20A1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575797

--


Antigen:
GCP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TUBGCP2

Gene Alias:
1700022B05Rik; a disintegrin and metalloprotease domain 8; Adam8; Gamma-ring complex protein 103 kDa; gamma-tubulin complex component 2; GCP2; GCP-2; Grip103; h103p; hGCP2; hGrip103; hSpc97; SPBC97; Spc97p; spindle pole body protein Spc97 homolog; Tubgcp2; tubulin gamma complex associated protein 2; tubulin, gamma complex associated protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10844, 309098, 74237

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q921G8, Q9BSJ2

Gene Symbols:
TUBGCP2

Immunogen:
Synthetic peptide corresponding to residues in Human TUBGCP2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG