PIPA575841

SERPINB3/SERPINB4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA575841-Each-of-1 In Stock ₹ 44,191.74

PIPA575841 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

SERPINB3/SERPINB4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SERPINB4

Gene Alias

1110001H02Rik; 1110013A16Rik; HsT1196; LEUPIN; Peptidase inhibitor 11; PI11; PI-11; protease inhibitor (leucine-serpin); protein T4-A; RGD1562868; SCC; SCCA; SCCA1; SCCA-1; SCCA2; SCCA-2; SCCA2/SCCA1 fusion protein; SCCA-PD; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; serine peptidase inhibitor, clade B, member 3A; serine protease inhibitor B3; serpin B3; Serpin B4; serpin family B member 3; serpin family B member 4; serpin peptidase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 4; Serpinb3; Serpinb3a; SERPINB4; spb3; Sqn5; Squamous cell carcinoma antigen 1; squamous cell carcinoma antigen 2; SSCA1; T4-A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20248, 304688, 498209, 6317, 6318

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P29508, P48594

Gene Symbols

Serpinb3, Serpinb3a, SERPINB4

Immunogen

Synthetic peptide corresponding to residues in Human SERPINB3/SERPINB4.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins
  • Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase
  • In 1985, Dr
  • Jim Travis and Dr
  • R.W
  • Carrell designated an emerging family of serine protease inhibitors as the serpin fam-ily, which share homology in both primary amino acid sequence and tertiary structure
  • Serpins contain a stretch of peptide that mimics a true substrate for a corresponding serine protease
  • Serine proteases bind to this substrate mimic in a 1:1 stoichiometric fashion and become catalytically inactive
  • Aberrant ex-pression of serpin family members can contribute to a number of conditions, including emphysema (a-1 antitrypsin deficiency), fatal bleeding (elastase to thrombin specificity) and thrombosis (antithrombin deficiency), and are indicators of cancer stage phenotypes (circulating levels of squamous cell carcinoma antigen, known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers)
  • Human chromosome position 18q21.3 contains a cluster of serpins, including a tandem duplication of the SCCA gene, plasminogen activator inhibitor type 2, and maspin
  • SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1
  • The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA575841

--


Antigen:
SERPINB3/SERPINB4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SERPINB4

Gene Alias:
1110001H02Rik; 1110013A16Rik; HsT1196; LEUPIN; Peptidase inhibitor 11; PI11; PI-11; protease inhibitor (leucine-serpin); protein T4-A; RGD1562868; SCC; SCCA; SCCA1; SCCA-1; SCCA2; SCCA-2; SCCA2/SCCA1 fusion protein; SCCA-PD; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3A; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; serine peptidase inhibitor, clade B, member 3A; serine protease inhibitor B3; serpin B3; Serpin B4; serpin family B member 3; serpin family B member 4; serpin peptidase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 4; Serpinb3; Serpinb3a; SERPINB4; spb3; Sqn5; Squamous cell carcinoma antigen 1; squamous cell carcinoma antigen 2; SSCA1; T4-A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20248, 304688, 498209, 6317, 6318

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P29508, P48594

Gene Symbols:
Serpinb3, Serpinb3a, SERPINB4

Immunogen:
Synthetic peptide corresponding to residues in Human SERPINB3/SERPINB4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575842

--


Antigen:
AKAP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKAP3

Gene Alias:
A kinase (PRKA) anchor protein 3; AKAP 110; AKAP110; Akap3; AKAP-3; A-kinase anchor protein 110 kDa; A-kinase anchor protein 3; A-kinase anchor protein, 110kDa; A-kinase anchoring protein 3; Cancer/testis antigen 82; CT82; epididymis luminal protein 159; Fibrous Sheath Protein of 95 kDa; fibrousheathin 1; Fibrousheathin I; fibrousheathin-1; FSP95; HEL159; PRKA3; protein kinase A binding protein AKAP 110; Protein kinase A-anchoring protein 3; SOB1; Sperm oocyte-binding protein; sperm oocyte-binding protein 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10566, 11642, 312720

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75969, O88987

Gene Symbols:
AKAP3

Immunogen:
Synthetic peptide corresponding to residues in Human AKAP3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575843

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Antigen:
LYL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LYL1

Gene Alias:
bHLHa18; Class A basic helix-loop-helix protein 18; LYL1; Lyl-1; LYL1, basic helix-loop-helix family member; lymphoblastic leukemia associated hematopoiesis regulator 1; lymphoblastic leukemia derived sequence 1; lymphoblastic leukemia-derived sequence 1; lymphoblastomic leukemia 1; protein lyl-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17095, 304663, 4066

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P12980, P27792, Q66HH3

Gene Symbols:
LYL1

Immunogen:
Synthetic peptide corresponding to residues in Human LYL1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575844

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Antigen:
ZNF76

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF76

Gene Alias:
2810027J07; BC025615; D6S229E; Zfp523; Zinc finger protein 523; zinc finger protein 76; zinc finger protein 76 (expressed in testis); ZNF523; Znf76

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
224656, 361809, 7629

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
B4F7E9, P36508, Q8BMU0

Gene Symbols:
Zfp523, ZNF76

Immunogen:
Synthetic peptide corresponding to residues in Human ZNF76.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG