PIPA575919

SRD5A1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA575919-Each-of-1 In Stock ₹ 44,277.30

PIPA575919 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

SRD5A1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SRD5A1

Gene Alias

0610031P22Rik; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; 4930435F02Rik; S5AR 1; SR type 1; Srd5a1; Srd5a-1; steroid 5 alpha-reductase 1; steroid 5-alpha-reductase 1; steroid 5-alpha-reductase type I; steroid-5-alpha-reductase 1; steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1); type 1 5alpha-reductase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24950, 6715, 78925

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P18405, P24008, Q68FF9

Gene Symbols

SRD5A1

Immunogen

Synthetic peptide corresponding to residues in Human SRD5A1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Steroid 5alpha-Reductase is an important enzyme in androgen physiology because it catalyzes the conversion of testosterone into the more potent 5alpha-dihydro-testosterone, which mediates androgen effects on target tissues
  • The enzyme exists as two isoforms: type 1, which is expressed mainly in the skin; and type 2, which is expressed mainly in the prostate
  • In cultured human skin cells, 5alpha-Reductase 1 shows heterogeneity of protein, and has different levels of transcriptional and translational expression
  • 5alpha-Reductase 1 is expressed in all portions of the hair follicle, whereas 5alpha-Reductase 2 is expressed only in mesenchymal portions
  • In addition, 5alpha-Reductase 1 is mainly expressed in human breast carcinoma and may play a role in the in situ production and actions of the potent androgen 5alpha-dihydrotestosterone, including inhibition of cancer cell proliferation in hormone-dependent human breast carcinoma
  • The 5alpha-Reductase-3alpha-hydroxysteroid dehydrogenase complex is present in the human brain, suggesting that the complex may be involved in the synthesis of neuroactive steroids or the catabolism of neurotoxic steroids.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA575919

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Antigen:
SRD5A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SRD5A1

Gene Alias:
0610031P22Rik; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; 4930435F02Rik; S5AR 1; SR type 1; Srd5a1; Srd5a-1; steroid 5 alpha-reductase 1; steroid 5-alpha-reductase 1; steroid 5-alpha-reductase type I; steroid-5-alpha-reductase 1; steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1); type 1 5alpha-reductase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24950, 6715, 78925

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P18405, P24008, Q68FF9

Gene Symbols:
SRD5A1

Immunogen:
Synthetic peptide corresponding to residues in Human SRD5A1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575920

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Antigen:
Drosha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DROSHA

Gene Alias:
1110013A17Rik; AI874853; Drosha; drosha ribonuclease III; drosha, double-stranded RNA-specific endoribonuclease; drosha, ribonuclease type III; ethanol induced 2; ETOHI2; HSA242976; MGC115770; nuclear RNase III Drosha; OTTHUMP00000220910; OTTHUMP00000220911; OTTHUMP00000220912; OTTHUMP00000220913; p241; Protein Drosha; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; RANSE3L; RGD1307626; ribonuclease 3; Ribonuclease III; ribonuclease III, nuclear; ribonuclease type III, nuclear; RN3; RNase III; RNASE3L; RNASEN

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14000, 29102, 310159

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5HZJ0, Q9NRR4

Gene Symbols:
DROSHA

Immunogen:
Synthetic peptide corresponding to residues in Human DROSHA.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575922

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Antigen:
RHD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RHD

Gene Alias:
blood group antigen D; blood group protein RHD; blood group Rh(D) polypeptide; CD240D; D antigen (DCS); DIIIc; Erythrocyte membrane glycoprotein Rh30; Rh; Rh blood group antigen Evans; Rh blood group D antigen; Rh blood group protein; Rh blood group, D anitgen; Rh blood group, D antigen; RH polypeptide 2; Rh30; Rh4; Rhced; RHD; RhD blood group antigen; RhD polypeptide; RhDCw; RHDel; RHDVA(TT); Rhesus blood group CE and D; Rhesus blood group D antigen allele DIII type 7; rhesus D antigen; Rhesus system D polypeptide; RhII; RhK562-II; Rhl1; Rh-like polypeptide; RhPI; RHPII; RHXIII; truncated rhesus blood group D antigen; truncated rhesus D

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19746, 6007, 60414

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O88298, Q02161, Q8CF94

Gene Symbols:
RHD

Immunogen:
Synthetic peptide corresponding to amino acids 168-213 of Human RHD.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA575923

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Antigen:
THNSL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
THNSL2

Gene Alias:
BC051244; FLJ10916; FLJ35504; RGD1309144; secreted osteoclastogenic factor of activated T cells; Secreted osteoclastogenic factor of activated T-cells; SOFAT; THNSL2; threonine synthase like 2; threonine synthase-like 2; threonine synthase-like 2 (bacterial); threonine synthase-like 2 (S. cerevisiae); THS2; TSH2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
232078, 297332, 55258

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5M7T9, Q80W22, Q86YJ6

Gene Symbols:
THNSL2

Immunogen:
Synthetic peptide corresponding to amino acids 103-148 in Human THNSL2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG