UGT1A9 Polyclonal Antibody, Invitrogen™

Description

• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
• UGT1A9 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites
• UGT1A9 is active on phenols.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites
• This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases
• The locus includes thirteen unique alternate first exons followed by four common exons
• Four of the alternate first exons are considered pseudogenes
• Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini
• Each first exon encodes the substrate binding site, and is regulated by its own promoter
• The enzyme encoded by this gene is active on phenols
• Publication Note: This RefSeq record includes a subset of the publications that are available for this gene
• Please see the Entrez Gene record to access additional publications.