PIPA576131
Calcineurin B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA576131-Each-of-1 | In Stock | ₹ 47,614.14 |
PIPA576131 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
Calcineurin B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPP3R1
Gene Alias
ALNB1; calcineurin B, type I (19kDa); calcineurin subunit B type 1; CALNB1; CaNB1; Cna2; Cnb; Cnb1; MCIP1; PP2B beta 1; PPP3R1; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); protein phospatase 3, regulatory subunit B, alpha isoform,type 1; protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3 regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19058, 29748, 5534
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P63098, P63100, Q63810
Gene Symbols
PPP3R1
Immunogen
Recombinant protein of human Calcineurin B.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
- Calcineurin is a Ser/Thr, calcium and calmodulin-dependent protein phosphatase that plays an essential role in the T cell activation pathway
- Calcineurin (also referred to as protein phosphatase 2B) is composed of two subunits; calcineurin A (CnA), a 60 kDa catalytic subunit which is highly homologous to protein phosphatases 1 and 2A; and a 19 kDa regulatory subunit, calcineurin B (CnB) which, like calmodulin, contains four EF-hand calcium binding sites
- Calcineurin-mediated dephosphorylation of the nuclear factor of activated T-cells (NF-AT) is essential for NF-AT activation, nuclear translocation, and early gene expression in T-cells
- The immunosuppressive drugs, cyclosporin A and FK506, when bound to the immunophilins, cyclophilin and FKBP respectively, inhibit dephosphorylation and activation of NF-AT by calcineurin
- This inhibition is caused by the immunosuppressant/immunophilin complex simultaneously binding to both CnA and CnB which does not inhibit the phosphatase activity of CnA, but rather blocks access of the substrate to the catalytic domain of CnA.
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Antigen: Calcineurin B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP3R1
Gene Alias: ALNB1; calcineurin B, type I (19kDa); calcineurin subunit B type 1; CALNB1; CaNB1; Cna2; Cnb; Cnb1; MCIP1; PP2B beta 1; PPP3R1; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); protein phospatase 3, regulatory subunit B, alpha isoform,type 1; protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3 regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19058, 29748, 5534
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P63098, P63100, Q63810
Gene Symbols: PPP3R1
Immunogen: Recombinant protein of human Calcineurin B.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Calcineurin B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP3R1
Gene Alias:
ALNB1; calcineurin B, type I (19kDa); calcineurin subunit B type 1; CALNB1; CaNB1; Cna2; Cnb; Cnb1; MCIP1; PP2B beta 1; PPP3R1; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); protein phospatase 3, regulatory subunit B, alpha isoform,type 1; protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3 regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19058, 29748, 5534
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P63098, P63100, Q63810
Gene Symbols:
PPP3R1
Immunogen:
Recombinant protein of human Calcineurin B.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TXNL4A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TXNL4A
Gene Alias: BMKS; D18Wsu98e; DIB1; Dim1; DIM1 protein homolog; ENSMUSG00000057130; SNRNP15; spliceosomal U5 snRNP-specific 15 kDa protein; thioredoxin like 4A; thioredoxin-like 4; thioredoxin-like 4A; thioredoxin-like protein 4A; Thioredoxin-like U5 snRNP protein U5-15kD; TXNL4; Txnl4a; U5-15kD; U5-15kDa
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10907, 27366
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P83876, P83877
Gene Symbols: TXNL4A
Immunogen: Recombinant protein of human TXNL4A.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TXNL4A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TXNL4A
Gene Alias:
BMKS; D18Wsu98e; DIB1; Dim1; DIM1 protein homolog; ENSMUSG00000057130; SNRNP15; spliceosomal U5 snRNP-specific 15 kDa protein; thioredoxin like 4A; thioredoxin-like 4; thioredoxin-like 4A; thioredoxin-like protein 4A; Thioredoxin-like U5 snRNP protein U5-15kD; TXNL4; Txnl4a; U5-15kD; U5-15kDa
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10907, 27366
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P83876, P83877
Gene Symbols:
TXNL4A
Immunogen:
Recombinant protein of human TXNL4A.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CHRNE
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CHRNE
Gene Alias: acetylcholine receptor; acetylcholine receptor epsilon; acetylcholine receptor subunit epsilon; acetylcholine receptor, nicotinic, epsilon (muscle); AchR epsilon subunit; Achre; AChrepsilon; ACHRG; Acre; cholinergic receptor; cholinergic receptor nicotinic epsilon subunit; cholinergic receptor, nicotinic epsilon; cholinergic receptor, nicotinic, epsilon (muscle); cholinergic receptor, nicotinic, epsilon polypeptide; CHRNE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; epsilon-subunit; FCCMS; gene for acetylcholine receptor epsilon subunit; MGC133376; nAChRE; nicotinic acetylcholine receptor epsilon subunit; SCCMS
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11448, 1145, 29422
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P09660, P20782, Q04844
Gene Symbols: CHRNE
Immunogen: Recombinant protein of human CHRNE.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CHRNE
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CHRNE
Gene Alias:
acetylcholine receptor; acetylcholine receptor epsilon; acetylcholine receptor subunit epsilon; acetylcholine receptor, nicotinic, epsilon (muscle); AchR epsilon subunit; Achre; AChrepsilon; ACHRG; Acre; cholinergic receptor; cholinergic receptor nicotinic epsilon subunit; cholinergic receptor, nicotinic epsilon; cholinergic receptor, nicotinic, epsilon (muscle); cholinergic receptor, nicotinic, epsilon polypeptide; CHRNE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; epsilon-subunit; FCCMS; gene for acetylcholine receptor epsilon subunit; MGC133376; nAChRE; nicotinic acetylcholine receptor epsilon subunit; SCCMS
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11448, 1145, 29422
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P09660, P20782, Q04844
Gene Symbols:
CHRNE
Immunogen:
Recombinant protein of human CHRNE.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PLA2R1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pla2r1
Gene Alias: 180 kDa secretory phospholipase A2 receptor; CLEC13C; C-type lectin domain family 13 member C; mannose receptor, C type 2; Mrc2; M-type receptor; phospholipase A2 receptor 1; phospholipase A2 receptor 1, 180kD; phospholipase A2 receptor 1, 180kDa; phospholipase A2, group IB, pancreas, receptor; Pla2g1br; PLA2G1R; PLA2-I receptor; PLA2IR; Pla2r; Pla2-r; PLA2R1; Secretory phospholipase A2 receptor; Soluble PLA2-R; Soluble secretory phospholipase A2 receptor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18779, 22925
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q13018, Q62028
Gene Symbols: Pla2r1
Immunogen: Recombinant protein of human PLA2R1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PLA2R1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pla2r1
Gene Alias:
180 kDa secretory phospholipase A2 receptor; CLEC13C; C-type lectin domain family 13 member C; mannose receptor, C type 2; Mrc2; M-type receptor; phospholipase A2 receptor 1; phospholipase A2 receptor 1, 180kD; phospholipase A2 receptor 1, 180kDa; phospholipase A2, group IB, pancreas, receptor; Pla2g1br; PLA2G1R; PLA2-I receptor; PLA2IR; Pla2r; Pla2-r; PLA2R1; Secretory phospholipase A2 receptor; Soluble PLA2-R; Soluble secretory phospholipase A2 receptor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18779, 22925
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q13018, Q62028
Gene Symbols:
Pla2r1
Immunogen:
Recombinant protein of human PLA2R1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG