PIPA576218

SPIN2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA576218-Each-of-1 In Stock ₹ 47,614.14

PIPA576218 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

SPIN2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPIN2B

Gene Alias

BC068162; dJ323P24.2; Spin2; SPIN-2; SPIN2_duplicate; SPIN2B; SPIN-2B; Spin2c; SPIN-2C; Spindlin 2B; spindlin family member 2B; spindlin family, member 2; spindlin family, member 2 duplicate; spindlin family, member 2B; spindlin family, member 2C; spindlin-2; spindlin-2B; Spindlin-2C; spindlin-like protein 2; spindlin-like protein 2B; Spindlin-like protein 2C; TDRD26; telomeric SPIN2 copy

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

278240, 474343

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q6NVE3, Q9BPZ2

Gene Symbols

SPIN2B, Spin2c

Immunogen

Recombinant protein of human SPIN2B.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA576352

--

Img

Thermo Scientific

PIPA576418

--

Img

Thermo Scientific

PIPA576674

--

Img

Thermo Scientific

PIPA576088

--

Img

Thermo Scientific

PIPA576880

--

Img

Thermo Scientific

PIPA576763

--

Img

Thermo Scientific

PIPA576161

--

Img

Thermo Scientific

PIPA575900

--

Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Human SPIN2 expressed by 2 IL3-dependent murine myeloid cell lines was moderately antiapoptotic following IL3 removal, but it was unable to block apoptosis induced by the chemotherapy agent doxorubicin
  • On the contrary, SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death
  • Also, SPIN2 did not combat the proapoptotic effects of Fas ligand stimulation in the Jurkat human T-cell line
  • Deletion of the C-terminal amino acids of SPIN2 diminished its antiapoptotic activity
  • In the murine myeloid cells, SPIN2 overexpression increased the cell number doubling times and slowed their rate of growth
  • There was also an increased percentage of cells in G2/M, which was more pronounced following IL3 withdrawal.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA576218

--


Antigen:
SPIN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPIN2B

Gene Alias:
BC068162; dJ323P24.2; Spin2; SPIN-2; SPIN2_duplicate; SPIN2B; SPIN-2B; Spin2c; SPIN-2C; Spindlin 2B; spindlin family member 2B; spindlin family, member 2; spindlin family, member 2 duplicate; spindlin family, member 2B; spindlin family, member 2C; spindlin-2; spindlin-2B; Spindlin-2C; spindlin-like protein 2; spindlin-like protein 2B; Spindlin-like protein 2C; TDRD26; telomeric SPIN2 copy

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
278240, 474343

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q6NVE3, Q9BPZ2

Gene Symbols:
SPIN2B, Spin2c

Immunogen:
Recombinant protein of human SPIN2B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA576219

--


Antigen:
RAB31

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAB31

Gene Alias:
1700093E07Rik; AI415285; GTP-binding protein Rab0; monomeric GTP-binding protein; Rab0; Rab22B; Rab31; RAB31, member RAS oncogene family; ras-related protein Rab-22B; Ras-related protein Rab-31

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
106572, 11031, 246324

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q13636, Q6GQP4, Q921E2

Gene Symbols:
RAB31

Immunogen:
Recombinant protein of human RAB31.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA576220

--


Antigen:
SESN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SESN2

Gene Alias:
Hi95; hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; RGD1566319; Ses2; SESN2; SEST2; sestrin 2; sestrin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
230784, 83667

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P58004, P58043

Gene Symbols:
SESN2

Immunogen:
Recombinant protein of human SESN2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA576221

--


Antigen:
MTCO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
mt-Co1

Gene Alias:
Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17708, 4512

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P00395, P00397

Gene Symbols:
mt-Co1

Immunogen:
Synthetic peptide of human COX1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG