PIPA576308

ARHGEF11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA576308-Each-of-1 In Stock ₹ 47,528.58

PIPA576308 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

ARHGEF11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARHGEF11

Gene Alias

Arhgef11; B930073M02; E130307F09; glutamate transporter EAAT4 associated protein 48; glutamate transporter EAAT4-associated protein 48; Gtrap48; KIAA0380; mKIAA0380; PDZ-RhoGEF; Prg; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF; RhoGEF glutamate transport modulator; RhoGEF glutamate transport modulator GTRAP48; RP11-356J7.2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

213498, 78966, 9826

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O15085, Q9ES67

Gene Symbols

ARHGEF11

Immunogen

Synthetic peptide of human ARHGEF11.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • ARHGEF11 is a 1527 amino acid protein with tandem dbl homology and pleckstrin homology domains, PDZ domain, two proline rich sequences and a regulatory G protein-signaling (RGS) sequence
  • It acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase, but not for RAC1 or CDC42 and acts as GTPase-activating protein (GAP) for GNA12 and GNA13
  • It forms a complex with G proteins and stimulates neurite through retraction Rho-dependent signals
  • ARHGEF11 increases glutamate transport 4-fold
  • It interacts with EAAT4 and modulates its uptake activity and perisynaptic distribution at glutamatergic synapses
  • It is known to induce the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia
  • It is ubiquitously expressed, in brain, lung, liver, kidney and skeletal muscle.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA576308

--


Antigen:
ARHGEF11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGEF11

Gene Alias:
Arhgef11; B930073M02; E130307F09; glutamate transporter EAAT4 associated protein 48; glutamate transporter EAAT4-associated protein 48; Gtrap48; KIAA0380; mKIAA0380; PDZ-RhoGEF; Prg; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; rho guanine nucleotide exchange factor 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF; RhoGEF glutamate transport modulator; RhoGEF glutamate transport modulator GTRAP48; RP11-356J7.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
213498, 78966, 9826

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O15085, Q9ES67

Gene Symbols:
ARHGEF11

Immunogen:
Synthetic peptide of human ARHGEF11.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA576309

--


Antigen:
DDX39

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX39A

Gene Alias:
2610307C23Rik; ATP-dependent RNA helicase DDX39; ATP-dependent RNA helicase DDX39A; BAT1; BAT1L; DDX39; Ddx39a; Ddxl; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; DEAD box protein 39; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39; DEAD-box helicase 39A; nuclear RNA helicase URH49; Nuclear RNA helicase, DECD variant of DEAD box family; UAP56-related helicase, 49 kDa; URH49

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10212, 68278, 89827

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O00148, Q5U216, Q8VDW0

Gene Symbols:
Ddx39, DDX39A

Immunogen:
Recombinant protein of human DDX39A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA576310

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Antigen:
MTX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTX2

Gene Alias:
1500012G02Rik; metaxin 2; Metaxin2; metaxin-2; Mitochondrial outer membrane import complex protein 2; MNCb-0780; Mtx2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10651, 53375

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75431, O88441

Gene Symbols:
MTX2

Immunogen:
Recombinant protein of human MTX2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA576313

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Antigen:
ARHGEF9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGEF9

Gene Alias:
9630036L12Rik; A230067K14; ARHDH9; ARHGEF9; Cdc42 guanine nucleotide exchange factor (GEF) 9; Cdc42 guanine nucleotide exchange factor 9; COLLYBISTIN; collybistin I; EIEE8; HPEM-2; hPEM-2 collybistin; KIAA0424; mKIAA0424; PEM2; PEM-2; PEM-2 homolog; rac/Cdc42 guanine nucleotide exchange factor 9; Rho guanine nucleotide exchange factor 9

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23229, 236915, 66013

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O43307, Q3UTH8, Q9QX73

Gene Symbols:
ARHGEF9

Immunogen:
Recombinant protein of human ARHGEF9.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG