PIPA576701
NLK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA576701-Each-of-1 | In Stock | ₹ 47,614.14 |
PIPA576701 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
NLK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLK
Gene Alias
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18099, 497961, 51701
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
D3ZSZ3, O54949, Q9UBE8
Gene Symbols
NLK
Immunogen
Recombinant full length Human NLK.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
- NLK is a serine/threonine kinase involved in signal transduction and cellular communication
- Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2
- Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1
- The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing
- The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs)
- Negative regulator of the canonical Wnt/beta-catenin signaling pathway
- Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1
- Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes
- Negative regulator of the Notch signaling pathway
- Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1
- Negative regulator of the MYB family of transcription factors.
Compare Similar Items
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Antigen: NLK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLK
Gene Alias: AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18099, 497961, 51701
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: D3ZSZ3, O54949, Q9UBE8
Gene Symbols: NLK
Immunogen: Recombinant full length Human NLK.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NLK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLK
Gene Alias:
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18099, 497961, 51701
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
D3ZSZ3, O54949, Q9UBE8
Gene Symbols:
NLK
Immunogen:
Recombinant full length Human NLK.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ABCA6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABCA6
Gene Alias: 6330565N06Rik; ABC transporter ABCA6; Abca6; ATP binding cassette subfamily A member 6; ATP-binding cassette A6; ATP-binding cassette sub-family A member 6; ATP-binding cassette transporter sub-family A member 6; ATP-binding cassette, subfamily A (ABC1), member 6; ATP-binding cassette, sub-family A (ABC1), member 6; EST155051
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23460, 303639, 76184
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.2
Gene Accession No.: Q8K441, Q8N139
Gene Symbols: ABCA6
Immunogen: Recombinant full length Human ABCA6.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ABCA6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABCA6
Gene Alias:
6330565N06Rik; ABC transporter ABCA6; Abca6; ATP binding cassette subfamily A member 6; ATP-binding cassette A6; ATP-binding cassette sub-family A member 6; ATP-binding cassette transporter sub-family A member 6; ATP-binding cassette, subfamily A (ABC1), member 6; ATP-binding cassette, sub-family A (ABC1), member 6; EST155051
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23460, 303639, 76184
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.2
Gene Accession No.:
Q8K441, Q8N139
Gene Symbols:
ABCA6
Immunogen:
Recombinant full length Human ABCA6.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AHCY
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AHCY
Gene Alias: AA987153; Acetylation; Adenosylhomocysteinase; adoHcyase; AHCY; AL024110; cb1079; CuBP; D150; dtp; ducttrip; hm:zeh1173; hm:zeh1364; Hydrolase; Liver copper-binding protein; NAD; Polymorphism; S-adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase; SAHH; wu:fj67b02
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 191, 269378
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P23526, P50247
Gene Symbols: AHCY
Immunogen: Recombinant full length Human AHCY.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
AHCY
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AHCY
Gene Alias:
AA987153; Acetylation; Adenosylhomocysteinase; adoHcyase; AHCY; AL024110; cb1079; CuBP; D150; dtp; ducttrip; hm:zeh1173; hm:zeh1364; Hydrolase; Liver copper-binding protein; NAD; Polymorphism; S-adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase; SAHH; wu:fj67b02
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
191, 269378
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P23526, P50247
Gene Symbols:
AHCY
Immunogen:
Recombinant full length Human AHCY.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ATL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATL1
Gene Alias: 4930435M24Rik; Adfsp; AD-FSP; ATL1; ATL1 alpha; ATL1 beta; ATL1 gamma; ATL1-delta; atlastin GTPase 1; atlastin1; atlastin-1; Bcl11B; BCL-11B; BCL11B/TRDC fusion; brain-specific GTP-binding protein; Ctip 2; CTIP2; CTIP-2; Fsp1; GBP3; GBP-3; GTP-binding protein 3; guanine nucleotide-binding protein 3; guanylate-binding protein 3; hGBP3; hRit1; hRIT1 alpha; HSN1D; Rit 1; Rit1; spastic paraplegia 3 protein A; Spastic paraplegia 3A homolog; SPG3; SPG3A; ZNF856B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 51062, 73991
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q8BH66, Q8WXF7
Gene Symbols: ATL1
Immunogen: Recombinant full length Human ATL1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ATL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATL1
Gene Alias:
4930435M24Rik; Adfsp; AD-FSP; ATL1; ATL1 alpha; ATL1 beta; ATL1 gamma; ATL1-delta; atlastin GTPase 1; atlastin1; atlastin-1; Bcl11B; BCL-11B; BCL11B/TRDC fusion; brain-specific GTP-binding protein; Ctip 2; CTIP2; CTIP-2; Fsp1; GBP3; GBP-3; GTP-binding protein 3; guanine nucleotide-binding protein 3; guanylate-binding protein 3; hGBP3; hRit1; hRIT1 alpha; HSN1D; Rit 1; Rit1; spastic paraplegia 3 protein A; Spastic paraplegia 3A homolog; SPG3; SPG3A; ZNF856B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
51062, 73991
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q8BH66, Q8WXF7
Gene Symbols:
ATL1
Immunogen:
Recombinant full length Human ATL1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG