PIPA576848

PIGR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA576848-Each-of-1 In Stock ₹ 47,443.02

PIPA576848 - Each of 1

₹ 47,443.02

In Stock

Quantity

1

Base Price: ₹ 47,443.02

GST (18%): ₹ 8,539.744

Total Price: ₹ 55,982.764

Antigen

PIGR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pigr

Gene Alias

hepatocellular carcinoma associated protein TB6; hepatocellular carcinoma-associated protein TB6; phosphatidylinositol glycan, class R; Pigr; Poly Ig receptor; poly-Ig receptor; polymeric immunoglobulin receptor; Secretory component; tb6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18703, 5284

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O70570, P01833

Gene Symbols

Pigr

Immunogen

Recombinant full length Human PIGR.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Polymeric IgA and IgM is produced and secreted by B cells in the lamina propria, which is beneath the mucosal lining of polarized epithelial cells
  • Polymeric immunoglobulin receptors, also designated pIgRs, are expressed on the basolateral surface of glandular epithelia and mediate transcellular transport of secretory immunoglobulin polymers across the epithelium
  • pIgR associates with secreted dimeric IgA and IgM molecules
  • During transcellular transport of these Ig polymers, pIgR undergoes proteolytic cleavage to generate a fragment called secretory component (SC), polymeric immunoglobulin receptor or poly-IG receptor
  • When immunoglobulin polymers associate with SC, they become resistant to enzymatic degradation during the transcytosis process
  • SC and the pIgR are crucial for proper mucosal immunity where they represent a molecular chaperone for polymeric Igs to remain intact and enter into body fluids
  • The human SC (pIgR) gene maps to chromosome 1q31-q41 and encodes a 764 amino acid protein
  • The receptor contains five units with homology to the variable (V) units of immunoglobulins and a transmembrane region that shares homology to certain immunoglobulin variable regions.

Compare Similar Items

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Thermo Scientific

PIPA576848

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Antigen:
PIGR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pigr

Gene Alias:
hepatocellular carcinoma associated protein TB6; hepatocellular carcinoma-associated protein TB6; phosphatidylinositol glycan, class R; Pigr; Poly Ig receptor; poly-Ig receptor; polymeric immunoglobulin receptor; Secretory component; tb6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18703, 5284

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O70570, P01833

Gene Symbols:
Pigr

Immunogen:
Recombinant full length Human PIGR.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA576849

--


Antigen:
TRPM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRPM2

Gene Alias:
9830168K16Rik; C79133; EC 3.6.1.13; EREG 1; EREG1; Estrogen-responsive element-associated gene 1 protein; KNP 3; KNP3; Long transient receptor potential channel 2; LTRPC 2; LTRPC2; LTrpC-2; MGC133383; NUDT9H; NUDT9L1; null; transient receptor potential cation channel subfamily M member 2; transient receptor potential cation channel, subfamily M, member 2; transient receptor potential channel 7; Transient receptor potential melastatin 2; transient receptor potential melastatin family 2; transient receptor protein 7; Trp7; TRPC 7; TRPC7; TRPM 2; Trpm2; Trpm2-predicted; Trrp7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7226

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O94759

Gene Symbols:
TRPM2

Immunogen:
Recombinant full length Human TRPM2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA576850

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Antigen:
C11orf30

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EMSY

Gene Alias:
2210018M11Rik; 2310016L09Rik; AU019521; AU019557; BRCA2-interacting transcriptional repressor EMSY; C11orf30; EMSY; EMSY BRCA2-interacting transcriptional repressor; EMSY protein; EMSY, BRCA2 interacting transcriptional repressor; EMSY, BRCA2-interacting transcriptional repressor; FLJ90741; GL002; protein EMSY; RGD1310712; RIKEN cDNA 2210018M11 gene; similar to EMSY protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
233545, 361607, 56946

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q7Z589, Q8BMB0

Gene Symbols:
EMSY

Immunogen:
Recombinant full length Human C11orf30.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA576852

--


Antigen:
KMT2E

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KMT2E

Gene Alias:
1810033J14Rik; 9530077A04Rik; D230038D11Rik; HDCMC04P; histone-lysine N-methyltransferase 2E; histone-lysine N-methyltransferase MLL5; Inactive histone-lysine N-methyltransferase 2E; Inactive lysine N-methyltransferase 2E; KMT2E; lysine (K)-specific methyltransferase 2E; lysine methyltransferase 2E; lysine N-methyltransferase 2E; MGC70452; MLL5; myeloid/lymphoid or mixed-lineage leukemia 5; myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia protein 5; Myeloid/lymphoid or mixed-lineage leukemia protein 5 homolog; NKp44L

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
311968, 55904, 69188

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q3UG20, Q8IZD2

Gene Symbols:
KMT2E

Immunogen:
Recombinant full length Human KMT2E.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG