PIPA576853

P4HTM Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA576853-Each-of-1 In Stock ₹ 47,528.58

PIPA576853 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

P4HTM

Classification

Polyclonal

Conjugate

Unconjugated

Gene

P4HTM

Gene Alias

4933406E20Rik; AI853847; BB128974; EGLN4; FLJ20262; HIFPH4; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4; hypoxia inducible factor prolyl 4 hydroxylase; hypoxia-inducible factor prolyl 4-hydroxylase; hypoxia-inducible factor prolyl hydroxylase 4; P4H TM; P4H with transmembrane domain; P4HTM; P4H-TM; PH 4; PH4; PH-4; PHD4; proline 4-hydroxylase; prolyl 4-hydroxylase, transmembrane; prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); Prolyl hydroxlase domain-containing 4; RGD1311848; Transmembrane prolyl 4-hydroxylase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54681, 74443

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q8BG58, Q9NXG6

Gene Symbols

P4HTM

Immunogen

Recombinant full length Human P4HTM.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA576776

--

Img

Thermo Scientific

PIPA576835

--

Img

Thermo Scientific

PIPA576784

--

Img

Thermo Scientific

PIPA577077

--

Img

Thermo Scientific

PIPA577058

--

Img

Thermo Scientific

PIPA575867

--

Img

Thermo Scientific

PIPA576638

--

Img

Thermo Scientific

PIPA576863

--

Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Prolyl hydroxylase 4 is a prolyl hydroxylase that modifies HIF-alpha
  • Classic prolyl hydroxylases are found in the endoplasmic reticulum and modify collagen, whereas HIF is an intracellular protein and the prolyl hydroxylase sites do not resemble those modifying collagen
  • HIF is a transcriptional complex that plays a critical role in oxygen homeostasis
  • Prolyl hydroxylase is an essential component of the pathway through which cells sense oxygen
  • In the presence of oxygen, prolyl hydroxylases convert specific prolyl residues in HIF-alpha to hydroxyproline, leading to HIF-alpha destruction
  • Low oxygen levels, sensed at the cellular level, cause the HIF conversion to be reduced so that HIF is stable and there is increased angiogenesis
  • Prolyl hydroxylase 4, specifically, catalyzes the posttranslational formation of 4-hydroxyproline in HIF alpha proteins
  • It may function as a cellular oxygen sensor and, under normoxic conditions, may targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA576853

--


Antigen:
P4HTM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
P4HTM

Gene Alias:
4933406E20Rik; AI853847; BB128974; EGLN4; FLJ20262; HIFPH4; HIF-PH4; HIF-prolyl hydroxylase 4; HPH-4; hypoxia inducible factor prolyl 4 hydroxylase; hypoxia-inducible factor prolyl 4-hydroxylase; hypoxia-inducible factor prolyl hydroxylase 4; P4H TM; P4H with transmembrane domain; P4HTM; P4H-TM; PH 4; PH4; PH-4; PHD4; proline 4-hydroxylase; prolyl 4-hydroxylase, transmembrane; prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); Prolyl hydroxlase domain-containing 4; RGD1311848; Transmembrane prolyl 4-hydroxylase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54681, 74443

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q8BG58, Q9NXG6

Gene Symbols:
P4HTM

Immunogen:
Recombinant full length Human P4HTM.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA576854

--


Antigen:
RAD54L2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD54L2

Gene Alias:
Androgen receptor-interacting protein 4; AR interacting protein 4; ARIP4; Helicase ARIP4; HSPC325; KIAA0809; Rad54 like 2; RAD54L2; RAD54-like 2 (S. cerevisiae); RAD54-like protein 2; RGD1561889; SRISNF2L

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23132

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9Y4B4

Gene Symbols:
RAD54L2

Immunogen:
Recombinant full length Human RAD54L2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA576855

--


Antigen:
TCF19

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TCF19

Gene Alias:
5730403J10Rik; AW495861; DAMA-213L4.5; SC 1; SC1; SC1 protein homolog; SC1(TCF19)-6; SC1(TCF19)-7; SC1-1; SCI(TCF19)-4; TCF 19; TCF19; TCF-19; Transcription factor 19; transcription factor 19-like protein; Transcription factor SC1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
106795, 406195, 6941

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q99KJ5, Q9Y242

Gene Symbols:
TCF19

Immunogen:
Recombinant full length Human TCF19.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA576856

--


Antigen:
CTCFL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ctcfl

Gene Alias:
BORIS; BORIS like protein; BORIS-like protein; Brother of the regulator of imprinted sites; Cancer/testis antigen 27; CCCTC-binding factor; CCCTC-binding factor (zinc finger protein)-like; CCCTC-binding factor like; CT27; CTCF paralog; CTCF T; CTCFL; CTCF-like protein; CTCF-T; dJ579F20.2; HMG 1L1; HMG-1L1; HMGB1L1; likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL); MGC163358; MGC169105; MGC169106; OTTMUSG00000016680; putative high mobility group protein 1-like 1; putative high mobility group protein B1-like 1; transcriptional repressor CTCFL; Zinc finger protein CTCF-T

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100360757, 140690, 664799

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
A2APF3, Q8NI51

Gene Symbols:
Ctcfl

Immunogen:
Recombinant full length Human CTCFL.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG