PIPA576904

PTS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA576904-Each-of-1 In Stock ₹ 47,614.14

PIPA576904 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

PTS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pts

Gene Alias

6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19286, 29498, 5805

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

P27213, Q03393, Q9R1Z7

Gene Symbols

Pts

Immunogen

Recombinant full length Human PTS.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • The tetrahydrobiopterin (BH4) cofactor is essential for hepatic hydroxylase, which is involved in phenylalanine degradation and catecholamine and serotonin biosynthesis
  • BH4 is also an essential and limiting cofactor for all types of nitric oxide synthase
  • BH4 deficiency results in hyperphenylalaninemia and monoamine neurotransmitter depletion and is most commonly due to autosomal recessive mutation in 6-pyruvoyltetrahydropterin synthase (PTPS), the second enzyme for BH4 biosynthesis
  • The active site of PTPS consists of the pterin-anchoring Glu A107 neighbored by two catalytic motifs: a Zn(II) binding site and an inter-subunit catalytic triad formed by Cys A42, Asp B88 and His B89
  • The active site of PTPS undergoes a Zn and Mg-dependent reaction that includes a triphosphate elimination, a stereospecific reduction and the oxidation of both side hydroxyl groups
  • The catalytic triad of PTPS is involved in the deprotonation of the side-chain carbons of substrates
  • In addition, Ser 19 of human PTPS may be a substrate for cGMP-dependent protein kinase type II phosphorylation in vivo, which is essential for normal activity of PTPS.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA576904

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Antigen:
PTS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pts

Gene Alias:
6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; 6-pyruvoyl-tetrahydropterin synthase; PTP synthase; PTPS; PTS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19286, 29498, 5805

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P27213, Q03393, Q9R1Z7

Gene Symbols:
Pts

Immunogen:
Recombinant full length Human PTS.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA576909

--


Antigen:
RNPC3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNPC3

Gene Alias:
2810441O16Rik; AI447568; C030014B17Rik; KIAA1839; Rbm40; RNA binding region (RNP1, RRM) containing 3; RNA recognition protein; RNA-binding motif protein 40; RNA-binding protein 40; RNA-binding region (RNP1, RRM) containing 3; RNA-binding region-containing protein 3; RNP; Rnpc3; SNRNP65; U11/U12 small nuclear ribonucleoprotein 65 kDa protein; U11/U12 snRNP 65 kDa protein; U11/U12 snRNP 65K; U11/U12-65K

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55599, 67225, 691538

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.2

Gene Accession No.:
Q3UZ01, Q4G055, Q96LT9

Gene Symbols:
RNPC3

Immunogen:
Recombinant full length Human RNPC3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA576911

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Antigen:
AGA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aga

Gene Alias:
Aga; AGU; Aspartylglucosaminidase; aspartylglucosylamine deaspartylase; ASRG; AW060726; GA; Glycosylasparaginase; Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain; N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11593, 175

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P20933, Q64191

Gene Symbols:
Aga

Immunogen:
Recombinant full length Human AGA.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA576912

--


Antigen:
AMPD3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ampd3

Gene Alias:
adenosine monophosphate deaminase (isoform E); adenosine monophosphate deaminase 3; AMP aminohydrolase; AMP deaminase 3; AMP deaminase H-type; AMP deaminase isoform E; Ampd; Ampd3; Erythrocyte AMP deaminase; erythrocyte type AMP deaminase; erythrocyte-specific AMP deaminase; heart-type AMPD; myoadenylate deaminase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11717, 272

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O08739, Q01432

Gene Symbols:
Ampd3

Immunogen:
Recombinant full length Human AMPD3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG