PIPA576935

SFRP4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA576935-Each-of-1 In Stock ₹ 47,443.02

PIPA576935 - Each of 1

₹ 47,443.02

In Stock

Quantity

1

Base Price: ₹ 47,443.02

GST (18%): ₹ 8,539.744

Total Price: ₹ 55,982.764

Antigen

SFRP4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SFRP4

Gene Alias

Ddc4; DDC-4 protein; Frizzled protein, human endometrium; frizzled related protein; frizzled-related protein; frizzled-related protein 4; FRP; FRP-4; FRPHE; MGC26498; secreted frizzled related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related sequence protein 4; Sfrp4; sFRP-4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20379, 6424, 89803

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6FHJ7, Q9JLS4, Q9Z1N6

Gene Symbols

SFRP4

Immunogen

Recombinant full length Human SFRP4.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Secreted Frizzled-Related Proteins (sFRPs) are a family of glycosylated Wnt antagonists characterized by a conserved cysteine-rich domain that shares homology with the cysteine-rich, extracellular domain Frizzled proteins use for the binding of Wnt proteins and receptors
  • Lacking the transmembrane and intracellular domains of the Frizzled proteins, sFRPs function as soluble modulators of the Wnt signaling pathway through the direct binding of Wnt proteins to this cysteine-rich domain, and the resultant inhibition of Wnt receptor binding and signaling capabilities
  • sFRP-4 is widely distributed in a variety of embryonic and adult tissues where it can function as a circulating antiangiogenic factor, a potent proapoptotic factor, an inhibitor of insulin secretion, and a suppressor of both tumor growth and metastatic potential through disruption of the Wnt signaling pathway
  • Research has demonstrated the existence of a direct correlation between the downregulation and/or absence of circulating sFRP-4 and the progression of several cancer types, including ovarian, endometrial, prostate and lung
  • Upregulation of circulating sFRP-4 has been linked to the deterioration of glucose metabolism in the case of type 2 diabetes, as well as the suppression of the keratinocyte hyperproliferation and epidermal hyperlasia that are definitive of psoriasis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA576935

--


Antigen:
SFRP4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SFRP4

Gene Alias:
Ddc4; DDC-4 protein; Frizzled protein, human endometrium; frizzled related protein; frizzled-related protein; frizzled-related protein 4; FRP; FRP-4; FRPHE; MGC26498; secreted frizzled related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related sequence protein 4; Sfrp4; sFRP-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20379, 6424, 89803

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6FHJ7, Q9JLS4, Q9Z1N6

Gene Symbols:
SFRP4

Immunogen:
Recombinant full length Human SFRP4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA576937

--


Antigen:
TCN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TCN1

Gene Alias:
haptocorin; haptocorrin; HC; protein R; TC I; TC1; TC-1; TCI; TCN1; transcobalamin 1; Transcobalamin I; transcobalamin I (vitamin B12 binding protein, R binder family); transcobalamin-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6947

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P20061

Gene Symbols:
TCN1

Immunogen:
Recombinant full length Human TCN1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA576938

--


Antigen:
TSPAN7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSPAN7

Gene Alias:
1200014P11Rik; A15; AI323365; CCG-B7; CD231; CD231 antigen; cell surface glycoprotein A15; DXS1692E; membrane component chromosome X surface marker 1; membrane component, X chromosome, surface marker 1; MRX58; Mxs1; neuroprotective protein 5; PE31; R74651; TALLA; TALLA homolog; TALLA-1; T-cell acute lymphoblastic leukemia associated antigen 1; T-cell acute lymphoblastic leukemia-associated antigen 1; tetraspanin 7; tetraspanin protein; tetraspanin-7; TM4SF2; TM4SF2b; transmembrane 4 superfamily 2b; transmembrane 4 superfamily member 2; Transmembrane 4, superfamily member 2 (cell surface glycoprotein A15); transmembrane protein A15; TSPAN7; tspan-7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21912, 363447, 7102

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P41732, Q62283

Gene Symbols:
TSPAN7

Immunogen:
Recombinant full length Human TSPAN7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA576942

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Antigen:
TIM17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TIMM17A

Gene Alias:
17kDa; fb82c12; Inner membrane preprotein translocase Tim17a; Mimt17; Mitochondrial import inner membrane translocase subunit Tim17-A; Mitochondrial import inner membrane translocase subunit Tim17-A-like protein; mitochondrial inner membrane translocase; mTim17a; preprotein translocase; Tim17; TIM17A; TIMM17; TIMM17A; timm17a protein; translocase of inner mitochondrial membrane 17 homolog A; translocase of inner mitochondrial membrane 17 homolog A (yeast); translocase of inner mitochondrial membrane 17a; translocator of inner mitochondrial membrane 17 kDa, a; translocator of inner mitochondrial membrane 17a; translocator of inner mitochondrial membrane a; wu:fb82c12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10440, 21854

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q99595, Q9Z0V8

Gene Symbols:
TIMM17A

Immunogen:
Recombinant full length Human TIM17.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG