PIPA577817

SCNN1B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA577817-Each-of-1 In Stock ₹ 49,239.78

PIPA577817 - Each of 1

₹ 49,239.78

In Stock

Quantity

1

Base Price: ₹ 49,239.78

GST (18%): ₹ 8,863.16

Total Price: ₹ 58,102.94

Antigen

SCNN1B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SCNN1B

Gene Alias

Amiloride-sensitive sodium channel subunit beta; amiloride-sensitive sodium channel subunit beta 1; amiloride-sensitive sodium channel subunit beta-like protein; BESC1; Beta ENaC; beta-ENaC; Beta-NaCH; betaxENaC; ENaC beta; ENaCb; enacbeta; epithelial Na(+) channel subunit beta; epithelial sodium channel beta-2 subunit; epithelial sodium channel beta-3 subunit; epithelial sodium channel, nonvoltage-gated 1, beta; nasal epithelial sodium channel beta subunit; nonvoltage-gated sodium channel 1 subunit beta; RNENACB; SCNEB; SCNN 1B; SCNN1B; scnn1b.L; scnn1b-a; scnn1b-b; sodium channel epithelial 1 beta subunit; sodium channel, non voltage gated 1 beta subunit; sodium channel, non voltage gated 1 beta subunit L homeolog; sodium channel, nonvoltage-gated 1 beta; sodium channel, nonvoltage-gated 1, beta; sodium channel, non-voltage-gated 1, beta subunit; sodium channel, nonvoltage-gated, type I, beta; XELAEV_18045378mg

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100754564, 20277, 24767, 378536, 6338

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

P37090, P51168, Q9WU38

Gene Symbols

SCNN1B, scnn1b.L

Immunogen

Produced against the C-terminal tail (amino acids 617-638) of rat beta ENaC (antibody designation 3755-2)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Hamster, Human, Mouse, Rat, X. laevis

Product Type

Antibody

Isotype

IgG

Description

  • 1 μg/mL of PA5-77817 was sufficient for detection of beta-ENaC in 20 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.∣Detects approximately 87kDa
  • Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride
  • Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells
  • Controls the reabsorption of sodium in kidney, colon, lung and sweat glands
  • Also plays a role in taste perception
  • Heterotetramer of two alpha, one beta and one gamma subunit
  • A delta subunit can replace the alpha subunit
  • Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2
  • Defects in SCNN1B are a cause of autosomal recessive pseudohypoaldosteronism type 1 (PHA1) [MIM:264350]
  • PHA1 is a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids
  • There are 2 forms of PHA1: the autosomal recessive form that is severe, and the dominant form which is more milder and due to defects in mineralocorticoid receptor
  • Autosomal recessive PHA1 is characterized by an often fulminant presentation in the neonatal period with dehydration, hyponatraemia, hyperkalaemia, metabolic acidosis, failure to thrive and weight loss
  • Defects in SCNN1B are a cause of Liddle syndrome
  • It is an autosomal dominant disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis
  • The disease is caused by constitutive activation of the renal epithelial sodium channel.

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Img

Thermo Scientific

PIPA577817

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Antigen:
SCNN1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCNN1B

Gene Alias:
Amiloride-sensitive sodium channel subunit beta; amiloride-sensitive sodium channel subunit beta 1; amiloride-sensitive sodium channel subunit beta-like protein; BESC1; Beta ENaC; beta-ENaC; Beta-NaCH; betaxENaC; ENaC beta; ENaCb; enacbeta; epithelial Na(+) channel subunit beta; epithelial sodium channel beta-2 subunit; epithelial sodium channel beta-3 subunit; epithelial sodium channel, nonvoltage-gated 1, beta; nasal epithelial sodium channel beta subunit; nonvoltage-gated sodium channel 1 subunit beta; RNENACB; SCNEB; SCNN 1B; SCNN1B; scnn1b.L; scnn1b-a; scnn1b-b; sodium channel epithelial 1 beta subunit; sodium channel, non voltage gated 1 beta subunit; sodium channel, non voltage gated 1 beta subunit L homeolog; sodium channel, nonvoltage-gated 1 beta; sodium channel, nonvoltage-gated 1, beta; sodium channel, non-voltage-gated 1, beta subunit; sodium channel, nonvoltage-gated, type I, beta; XELAEV_18045378mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100754564, 20277, 24767, 378536, 6338

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P37090, P51168, Q9WU38

Gene Symbols:
SCNN1B, scnn1b.L

Immunogen:
Produced against the C-terminal tail (amino acids 617-638) of rat beta ENaC (antibody designation 3755-2)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA577821

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Antigen:
PDI

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
P4hb

Gene Alias:
1810041F13Rik; AI661267; CaO19.12595; cellular thyroid hormone binding protein; cellular thyroid hormone-binding protein; CLCRP1; collagen prolyl 4-hydroxylase beta; DSI; Endoplasmic reticulum resident protein 59; Eps1p; ER protein 59; ERBA2L; ERp59; GIT; glutathione-insulin transhydrogenase; I79_002399; LOW QUALITY PROTEIN: protein disulfide-isomerase A2; MFP1; P4HB; p4hb.L; P4Hbeta; p55; p58; Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDI (E.C.5.3.4.1); PDI1; PDI1P; Pdia1; pdia2; pdia2.L; PDIP; Pdipl; PDIR; PHDB; PO4DB; PO4HB; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide; PROHB; prolyl 4-hydroxylase beta polypeptide; Prolyl 4-hydroxylase subunit beta; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase subunit beta L homeolog; prolyl 4-hydroxylase, beta polypeptide L homeolog; prolyl 4-hydroxylase, beta polypeptide; prolyl 4-hydroxylase, beta subunit; protein disulfide isomerase; protein disulfide isomerase (pancreas) like; Protein disulfide isomerase (Prolyl 4-hydroxylase, beta polypeptide); protein disulfide isomerase A2; protein disulfide isomerase associated 2; protein disulfide isomerase family A member 2; protein disulfide isomerase family A member 2 L homeolog; protein disulfide isomerase family A, member 1; protein disulfide isomerase family A, member 2; protein disulfide isomerase PDI1; protein disulfide isomerase, pancreatic; protein disulfide isomerase/oxidoreductase; protein disulfide isomerase-associated 1; protein disulfide isomerase-associated 2; protein disulfide-isomerase; Protein disulfide-isomerase A2; protocollagen hydroxylase; Rho GDP dissociation inhibitor gamma; testicular secretory protein Li 32; Thbp; Thioredoxin-related glycoprotein 1; thyroid hormone-binding protein p55; TRG1; XELAEV_18043753mg; XELAEV_18045582mg; XPDIp; YCL043C; YCL313; YCL43C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100135700, 100689433, 100733944, 110255932, 18453, 25506, 281373, 399040, 399248, 483369, 5034

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P04785, P05307, P07237, P09103, Q8R4U2

Gene Symbols:
P4hb, p4hb.L, pdia2.L

Immunogen:
Rat PDI synthetic peptide (409-509 aa C-terminal) conjugated to KLH

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Guinea Pig, Hamster, Human, Ovine, Porcine, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA577824

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Antigen:
HSPE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HSPE1

Gene Alias:
10 kDa chaperonin; 10 kDa heat shock protein, mitochondrial; 10 kDa heat shock protein, mitochondrial; MOB-like protein phocein; 10kDa; 10kDa Chaperonin; CH10; chaperonin 10; Cpn 10; CPN10; cpn10 protein; early pregnancy factor; early-pregnancy factor; EPF; GROES; Heat shock 10 kD protein 1 (chaperonin 10); heat shock 10 kDa protein 1 (chaperonin 10); heat shock 10 protein 1; heat shock 105kDa/110kDa protein 1; heat shock 10kD protein; heat shock 10kD protein 1 (chaperonin 10); heat shock 10kDa protein 1; heat shock 10kDa protein 1 (chaperonin 10); heat shock protein; heat shock protein 1 (chaperonin 10); heat shock protein 105; heat shock protein 105 kDa; heat shock protein 105 kDa; LOW QUALITY PROTEIN: heat shock protein 105 kDa; heat shock protein family E (Hsp10) member 1; heat shock protein family E (Hsp10) member 1 L homeolog; heat shock protein family H (Hsp110) member 1; HSP; hsp10; hsp105; hsp105a; hsp105b; hsp110; Hspe1; hspe1.L; Hsph1; hsph1-a; hsph1-b; mitochondrial 10 kDa

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100350401, 100357698, 106024963, 15528, 25462, 281833, 3336, 394775, 397575, 414669, 478855

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide; pH 7.3

Gene Accession No.:
P26772, P61603, P61604, Q64433

Gene Symbols:
HSPE1, hspe1.L, LOC100357698

Immunogen:
Human Cpn10 peptide AA 91-101

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA577828

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Antigen:
HSP70

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HSPA1B

Gene Alias:
68 kDa heat shock protein; 70 kda heat shock protein-2; 70 kilodalton heat shock protein; 87A; 87A locus; 87C locus; Bb; CG18743; CG31359; CG31359-PA; CG31366; CG31366-PA; CG31449; CG6489; chaperone; dHSP70; dhsp70Aa; Dmel\CG31359; Dmel\CG31366; Dmel_CG31359; Dmel_CG31366; Dm-hsp70; DmHSP70AA; DMHSP7D1; dnaK-type molecular chaperone HSP70-1; epididymis secretory protein Li 103; Hcp70.1; heat shock 10kDa protein 1-like; heat shock 70; heat shock 70 kD protein 1; heat shock 70 kD protein 2; heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 1-Hom; Heat shock 70 kDa protein 1L; heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 2; Heat shock 70 kDa protein 3; heat shock 70 kDa-like protein 1; heat shock 70kD protein 1A; heat shock 70kD protein 1B; heat shock 70kD protein 1B (mapped); heat shock 70kD protein-like 1; heat shock 70kDa protein 1A; heat shock 70kDa protein 1B; heat shock 70kDa protein 1-like; heat shock cognate 70-kd protein, tandem duplicate 2; Heat shock protein; heat shock protein 1A; heat shock protein 1B; heat shock protein 1-like; heat shock protein 70; heat shock protein 70.1; heat shock protein 70.2; heat shock protein 70-1; Heat shock protein 70-1l; Heat shock protein 70Aa; Heat shock protein 70Ab; Heat shock protein 70Ba; Heat shock protein 70Bb; Heat shock protein 70Bc; heat shock protein cognate 70, testis; heat shock protein family A (Hsp70) member 1 like; heat shock protein family A (Hsp70) member 1A; heat shock protein family A (Hsp70) member 1B; heat shock protein, 70 kDa 1; heat shock protein, 70 kDa 3; heat shock protein-70; heat shock-induced protein; heat shock-related protein hsc70t; heat-shock 70-kilodalton protein 1A; heat-shock 70-kilodalton protein 1B; heat-shock protein 70; Heat-shock-protein-70Aa; Heat-shock-protein-70Bb; HEL S 103; HEL-S-103; hs70; Hsc70t; HSP; Hsp 70; hsp68; Hsp70; Hsp-70; HSP70 1; HSP70 1B; HSP70 2; hsp70 87A; hsp70 87C; hsp70 Aa; HSP70 AceyltK77; hsp70(87A); Hsp70(87C); HSP70.1; HSP70.1/2; HSP70.1/HSP70.2; HSP70.2; Hsp70.3; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-1B; HSP70-1L; HSP70-2; Hsp70-3; HSP70-87A7; HSP70-87C1; hsp70a; hsp70A1; Hsp70A7d; Hsp70Aa; Hsp-70Aa; Hsp70Aa-PA; Hsp70Ab; Hsp70B; Hsp70Ba; Hsp70Bb; Hsp70Bbc; Hsp70Bb-PA; Hsp70Bc; HSP70-HOM; HSP70I; HSP70T; HSP72; Hspa1; Hspa1a; HSPA1B; Hspa1l; Hspa2; HSPA4; Hspa70; HSX70; hum70t; inducible heat shock protein 70; LP05203p; LP05233p; LP08776p; Major heat shock 70 kDa protein Aa; Major heat shock 70 kDa protein Ab; Major heat shock 70 kDa protein Ba; Major heat shock 70 kDa protein Bb; Major heat shock 70 kDa protein Bc; Msh5; protein 70; si:ch73-46h18.6; si:dkeyp-69e1.1; Spermatid-specific heat shock protein 70; zgc:174006

Host Species:
Chicken

Purification Method:
PEG precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
15482, 15511, 15512, 15525, 193740, 24472, 24963, 266759, 294254, 3303, 3304, 3305, 3306, 3308, 403612, 474680, 480355, 60460

Content And Storage:
-20°C

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
O88600, P0DMV8, P0DMV9, P0DMW0, P0DMW1, P14659, P16627, P17156, P17879, P34931, P34932, P54652, P55063, Q2TFN9, Q61316, Q61696, Q7YQC6

Gene Symbols:
hsp70, HSPA1A, HSPA1B, Hspa1l, HSPA2, HSPA4

Immunogen:
Full length Human HSP70

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgY