PIPA577874

Axl Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA577874-Each-of-1 In Stock ₹ 47,528.58

PIPA577874 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

Axl

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AXL

Gene Alias

Adhesion-related kinase; AI323647; ARK; AXL; AXL oncogene; AXL receptor tyrosine kinase; AXL transforming sequence/gene; AZF1; JTK11; oncogene AXL; sAXL; soluble AXL; Tyro7; Tyrosine-protein kinase receptor UFO; Ufo; ufo oncogene homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

308444, 558

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.92 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P30530

Gene Symbols

AXL

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human AXL. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Positive Control: human AXL-transfected 293T Predicted Reactivity: Mouse (85%), Pig (81%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • AXL is a chronic myelogenous leukemia-associated oncogene that is also associated with colon cancer and melanoma
  • The AXL protein is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6, and is involved in the stimulation of cell proliferation
  • TAM receptors are also involved in phagocytosis of apoptotic cells
  • Mice lacking all three TAM receptors have several degenerative phenotypes linked to inefficient removal of apoptotic cells and membranes (e.g., in the retina and the male reproductive tract) and develop a severe autoimmune phenotype akin to systemic lupus erythematosus, including the production of broad spectrum auto-antibodies
  • In addition, Axl may function as a putative entry receptor for filoviruses
  • Axl is also used to identify a specific subpopulation of human blood dendritic cells, also referred to as Siglec 6+/Axl+ dendritic cells
  • Cellular expression of Axl can be upregulated by TLR ligands, such as LPS or poly I:C
  • Soluble Axl is generated by proteolytic cleavage of the membrane form
  • Increased plasma levels may be indicative of inflammation and cancer.

Compare Similar Items

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Img

Thermo Scientific

PIPA577874

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Antigen:
Axl

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AXL

Gene Alias:
Adhesion-related kinase; AI323647; ARK; AXL; AXL oncogene; AXL receptor tyrosine kinase; AXL transforming sequence/gene; AZF1; JTK11; oncogene AXL; sAXL; soluble AXL; Tyro7; Tyrosine-protein kinase receptor UFO; Ufo; ufo oncogene homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
308444, 558

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.92 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P30530

Gene Symbols:
AXL

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human AXL. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA577876

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Antigen:
Phospho-Bcl-2 (Ser70)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Human Bcl-2 (phospho Ser70). The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA577877

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Antigen:
Phospho-Bcl-2 (Ser87)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
2.06 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Bcl-2 (phospho Ser87). The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA577879

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Antigen:
BLK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BLK

Gene Alias:
B lymphocyte kinase; B lymphoid kinase; B lymphoid tyrosine kinase; Blk; BLK nonreceptor tyrosine kinase; BLK proto-oncogene, Src family tyrosine kinase; MGC10442; MODY11; p55-Blk; tyrosine-protein kinase Blk

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
640

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
2.21 mg/mL

Formulation:
0.1M tris glycine with 0.1M glycine, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P51451

Gene Symbols:
BLK

Immunogen:
Recombinant protein encompassing a sequence within the center region of human BLK. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG