PIPA578003

HLA-DQB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA578003-Each-of-1 In Stock ₹ 47,015.22

PIPA578003 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

HLA-DQB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-DQB1

Gene Alias

CELIAC1; DQ beta 1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3119

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.7 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P01920

Gene Symbols

HLA-DQB1

Immunogen

Recombinant protein encompassing a sequence within the center region of human HLA DQB1. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Positive Control: Raji Predicted reactivity: Human (89%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • HLA-DRB1 belongs to the HLA class II beta chain paralogs
  • The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane
  • It plays a central role in the immune system by presenting peptides derived from extracellular proteins
  • Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
  • The beta chain is approximately 26-28 kDa
  • It is encoded by 6 exons
  • Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail
  • Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
  • Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5
  • DRB1 is present in all individuals
  • Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5
  • There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

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Thermo Scientific

PIPA578003

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Antigen:
HLA-DQB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DQB1

Gene Alias:
CELIAC1; DQ beta 1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3119

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.7 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P01920

Gene Symbols:
HLA-DQB1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human HLA DQB1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA578005

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Antigen:
HMGB1/HMGB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HMGB2

Gene Alias:
Ac2-008; amphoterin; C80539; DEF; heparin-binding protein p30; high mobility group 1; high mobility group box 1; high mobility group box 2; high mobility group protein 1; High mobility group protein 2; high mobility group protein B1; High mobility group protein B2; high-mobility group (nonhistone chromosomal) protein 1; high-mobility group (nonhistone chromosomal) protein 2; high-mobility group box 1; high-mobility group box 2; HMG1; HMG-1; HMG2; HMG-2; HMG3; Hmgb1; Hmgb2; p30; SBP-1; Sulfoglucuronyl carbohydrate binding protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15289, 25459, 29395, 3146, 3148, 97165

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P09429, P26583, P30681, P52925, P63158, P63159

Gene Symbols:
HMGB1, HMGB2

Immunogen:
Full length human HMGB1/HMGB2 Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA578006

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Antigen:
HMGB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hmgb2

Gene Alias:
C80539; high mobility group box 2; high mobility group protein 2; High mobility group protein B2; high-mobility group (nonhistone chromosomal) protein 2; high-mobility group box 2; HMG 2; HMG B2; Hmg2; HMG-2; HMGB2; HMG-B2; HMGB-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3148

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.7 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P26583

Gene Symbols:
Hmgb2

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human HMGB2. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA578008

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Antigen:
HMGA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HMGA1

Gene Alias:
AL023995; HGNC:5010; high mobility group AT-hook 1; high mobility group AT-hook protein 1; high mobility group HMGA1A; high mobility group HMGA1B; high mobility group protein; high mobility group protein 1A; high mobility group protein A1; high mobility group protein A1A; high mobility group protein A1B; high mobility group protein HMG-I/HMG-Y; high mobility group protein I; high mobility group protein R; high mobiliy group protein A1B; high-mobility group (nonhistone chromosomal) protein isoforms I and Y; HMGA1; Hmga1a; Hmga1b; Hmgi; HMG-I(Y); HMGIY; HMG-R; Hmgy; MGC12816; MGC4242; MGC4854; nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y; non-histone protein; non-histone protein; HMGA1A; non-histone protein; HMGA1B; OTTHUMP00000016222; OTTHUMP00000016223; OTTHUMP00000016224; OTTHUMP00000039618

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3159

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P17096

Gene Symbols:
HMGA1

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HMGA1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG