PIPA578030

JAK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578030-Each-of-1 In Stock ₹ 47,015.22

PIPA578030 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

JAK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK3

Gene Alias

Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3718

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1.11 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P52333

Gene Symbols

JAK3

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human JAK3. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Positive Control: NCI-H929 Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family
  • JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • However, active JAK1 may be required for complex responses
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.

Compare Similar Items

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Img

Thermo Scientific

PIPA578030

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Antigen:
JAK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK3

Gene Alias:
Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.11 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P52333

Gene Symbols:
JAK3

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human JAK3. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578031

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Antigen:
JARID2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JARID2

Gene Alias:
JARD2 antibody; Jarid2; Jmj; jumonji; jumonji and AT-rich interaction domain containing 2; jumonji homolog; jumonji, AT rich interactive domain 2; jumonji, AT rich interactive domain 2 protein; jumonji/ARID domain-containing protein 2; jumonji-like protein; LOW QUALITY PROTEIN: protein Jumonji; protein Jumonji

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16468, 3720

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q62315, Q92833

Gene Symbols:
JARID2

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human JARID2. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578032

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Antigen:
JARID2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JARID2

Gene Alias:
JARD2 antibody; Jarid2; Jmj; jumonji; jumonji and AT-rich interaction domain containing 2; jumonji homolog; jumonji, AT rich interactive domain 2; jumonji, AT rich interactive domain 2 protein; jumonji/ARID domain-containing protein 2; jumonji-like protein; LOW QUALITY PROTEIN: protein Jumonji; protein Jumonji

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16468, 3720

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q62315, Q92833

Gene Symbols:
JARID2

Immunogen:
Recombinant protein encompassing a sequence within the center region of human JARID2. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578033

--


Antigen:
KCNN4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kcnn4

Gene Alias:
DHS2; HIK1; hIKCa1; hKCa4; hSK4; IK; IK1; IKCa; IKCA1; intermediate conductance calcium-activated potassium channel protein 1; intermediate conductance calcium-activated potassium channel protein 4; intermediate conductance K channel; intermediate-conductance Ca-activated K channel; intermediate-conductance calcium-activated potassium channel; KCa3.1; KCA4; KCNN 4; KCNN4; mIKCa1; potassium calcium-activated channel subfamily N member 4; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel; putative Gardos channel; rKCNN4c; rSK4; SK4; SKCa 4; SKCa4; SKCas; small conductance calcium-activated potassium channel 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3783

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.11 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O15554

Gene Symbols:
Kcnn4

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human KCNN4. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG