PIPA578049
Phospho-SMAD2 (Ser245, Ser250, Ser255) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578049-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA578049 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
Phospho-SMAD2 (Ser245, Ser250, Ser255)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMAD2
Gene Alias
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4087
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1.16 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q15796
Gene Symbols
SMAD2
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human SMAD2 (phospho Ser245/Ser250/Ser255). The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Description
- Positive Control: MCF-7, MCF-7 (starvation 4hr + TGF-beta 20 ng/mL treatment for 16 hr), MCF-7 (TGF-beta 20 ng/mL treatment for 24 hr) Predicted Reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
- SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
- Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
- In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
- The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
- The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
- Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.
Compare Similar Items
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Antigen: Phospho-SMAD2 (Ser245, Ser250, Ser255)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD2
Gene Alias: 7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4087
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1.16 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q15796
Gene Symbols: SMAD2
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human SMAD2 (phospho Ser245/Ser250/Ser255). The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-SMAD2 (Ser245, Ser250, Ser255)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD2
Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4087
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1.16 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q15796
Gene Symbols:
SMAD2
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human SMAD2 (phospho Ser245/Ser250/Ser255). The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SMAD5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD5
Gene Alias: 1110051M15Rik; AI451355; DKFZp781C1895; DKFZp781O1323; dwarfin-C; DWFC; Dwf-C; hSmad5; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; Madh5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 5; mSmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5; SMAD5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4090
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ChIP Assay, Immunocytochemistry, Western Blot
Concentration: 1.23 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q99717
Gene Symbols: SMAD5
Immunogen: Recombinant protein encompassing a sequence within the center region of human SMAD5. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SMAD5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD5
Gene Alias:
1110051M15Rik; AI451355; DKFZp781C1895; DKFZp781O1323; dwarfin-C; DWFC; Dwf-C; hSmad5; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; Madh5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 5; mSmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5; SMAD5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4090
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ChIP Assay, Immunocytochemistry, Western Blot
Concentration:
1.23 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q99717
Gene Symbols:
SMAD5
Immunogen:
Recombinant protein encompassing a sequence within the center region of human SMAD5. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MAP1B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP1B
Gene Alias: A230055D22; AI843217; claustrin; DKFZp686E1099; DKFZp686F1345; FLJ38954; futsch; I79_010564; LC1; MAP1 light chain LC1; MAP1(X); MAP1.2; MAP1B; MAP-1B; MAP1B heavy chain; MAP5; microtubule associated protein 1B; microtubule associated protein 1B; microtubule-associated protein 1B; microtubule-associated protein 1B; Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)); microtubule-associated protein 5; Mtap1b; Mtap5; Mtap-5; Neuraxin; PPP1R102; protein phosphatase 1, regulatory subunit 102
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17755, 29456, 4131
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.28 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: P14873, P15205, P46821
Gene Symbols: MAP1B
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human MAP1B. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MAP1B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP1B
Gene Alias:
A230055D22; AI843217; claustrin; DKFZp686E1099; DKFZp686F1345; FLJ38954; futsch; I79_010564; LC1; MAP1 light chain LC1; MAP1(X); MAP1.2; MAP1B; MAP-1B; MAP1B heavy chain; MAP5; microtubule associated protein 1B; microtubule associated protein 1B; microtubule-associated protein 1B; microtubule-associated protein 1B; Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)); microtubule-associated protein 5; Mtap1b; Mtap5; Mtap-5; Neuraxin; PPP1R102; protein phosphatase 1, regulatory subunit 102
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17755, 29456, 4131
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.28 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
P14873, P15205, P46821
Gene Symbols:
MAP1B
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human MAP1B. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MCM6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mcm6
Gene Alias: ASP-l1; D1Wsu22e; DNA replication licensing factor MCM6; intestinal DNA replication protein; MCG40308; Mcm6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); Mcmd6; mini chromosome maintenance deficient 6; minichromosome maintenance complex component 6; minichromosome maintenance deficient (mis5, S. pombe) 6; minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae); Mis5; Mis5 homolog; p105MCM
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4175
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.14 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q14566
Gene Symbols: Mcm6
Immunogen: Recombinant protein encompassing a sequence within the center region of human MCM6. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MCM6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mcm6
Gene Alias:
ASP-l1; D1Wsu22e; DNA replication licensing factor MCM6; intestinal DNA replication protein; MCG40308; Mcm6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); Mcmd6; mini chromosome maintenance deficient 6; minichromosome maintenance complex component 6; minichromosome maintenance deficient (mis5, S. pombe) 6; minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae); Mis5; Mis5 homolog; p105MCM
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4175
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.14 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q14566
Gene Symbols:
Mcm6
Immunogen:
Recombinant protein encompassing a sequence within the center region of human MCM6. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG