PIPA578062

MLH1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578062-Each-of-1 In Stock ₹ 50,309.28

PIPA578062 - Each of 1

₹ 50,309.28

In Stock

Quantity

1

Base Price: ₹ 50,309.28

GST (18%): ₹ 9,055.67

Total Price: ₹ 59,364.95

Antigen

MLH1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mlh1

Gene Alias

1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4292

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.83 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P40692

Gene Symbols

Mlh1

Immunogen

Recombinant protein encompassing a sequence within the center region of human MLH1. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Positive Control: Raji, human MLH1-transfected 293T Predicted Reactivity: Mouse (95%), Rat (94%), Zebrafish (80%), Xenopus laevis (84%), Pig (95%), Bovine (95%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • MLH1 is a DNA mismatch repair protein
  • The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time
  • An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI)
  • These defects in DNA repair pathways have been related to human carcinogenesis
  • The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC)
  • MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process
  • It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA578062

--


Antigen:
MLH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4292

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.83 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P40692

Gene Symbols:
Mlh1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human MLH1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578063

--


Antigen:
MRE11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mre11

Gene Alias:
ATLD; AT-like disease; DNA recombination and repair protein; double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; meiotic recombination 11 homolog A (S. cerevisiae); mmMRE11A; MRE11; MRE11 double strand break repair nuclease A; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog A, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 meiotic recombination 11-like protein A; MRE11A; MRE11B; MRX complex nuclease subunit; NGS1; RAD58; XRS4; YM9959.06C; YMR224C

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4361

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
0.57 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P49959

Gene Symbols:
Mre11

Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human Mre11. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578064

--


Antigen:
MSX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MSX2

Gene Alias:
BB122635; CRS2; FPP; homeo box, msh-like 2; homeobox protein Hox-8; Homeobox protein Hox-8-1; homeobox protein MSX-2; homeobox, msh-like 2; HOX8; Hox-8; Hox8.1; Hox-8.1; MSH; msh homeo box 2; msh homeo box homolog 2; msh homeobox 2; msh homeobox homolog 2; MSX2; Msx-2; muscle segmentation homologue (MSX2); PFM; PFM1; Unknown (protein for MGC:142681)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17702, 4488

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P35548, Q03358

Gene Symbols:
MSX2

Immunogen:
Recombinant protein encompassing a sequence within the center region of human MSX2. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578066

--


Antigen:
MYL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYL2

Gene Alias:
cardiac myosin light chain 2; cardiac myosin light chain-2; cardiac ventricular myosin light chain 2; CMH10; DKFZp779C0562; hypothetical protein LOC677750; Mlc2; MLC-2; mLc2b; MLC-2s/v; MLC2V; MLC-2v; myl2; myl2b; Mylpc; myosin light chain 2; myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2V; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; myosin light chain-2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin regulatory light chain 2b; myosin regulatory light chain ventricular isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light chain 2b, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin, light polypeptide 2b, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; ventricular myosin light chain 2; ventricular myosin regulatory light chain; zgc:136848

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17906, 363925, 4633

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.32 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P08733, P10916, P51667

Gene Symbols:
MYL2

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Myosin Light Chain 2. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG