PIPA578208
TSC1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578208-Each-of-1 | In Stock | ₹ 47,528.58 |
PIPA578208 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,528.58
GST (18%): ₹ 8,555.144
Total Price: ₹ 56,083.724
Antigen
TSC1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSC1
Gene Alias
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
64930, 7248
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.38 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q92574, Q9EP53
Gene Symbols
TSC1
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human Hamartin/TSC1. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: 293T, A431, HeLa, HepG2, U87-MG, SK-N-SH, IMR32, SK-N-AS Predicted Reactivity: Rat (80%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes
- The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors
- TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high
- Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 decreases the ability of Rheb to stimulate TOR activity
- This is supported by experiments showing overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth
- A shorter 40 kDa isoform of TSC1 has been shown to exist but its function is unknown.
Compare Similar Items
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Antigen: TSC1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC1
Gene Alias: hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 64930, 7248
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.38 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q92574, Q9EP53
Gene Symbols: TSC1
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Hamartin/TSC1. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TSC1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC1
Gene Alias:
hamartin; HGNC:12362; Kiaa0243; LAM; MGC86987; OTTHUMP00000022439; OTTHUMP00000198378; TSC; Tsc1; tuberous sclerosis 1; tuberous sclerosis 1 protein; Tuberous sclerosis 1 protein homolog; tumor suppressor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
64930, 7248
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.38 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q92574, Q9EP53
Gene Symbols:
TSC1
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human Hamartin/TSC1. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TTF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ttf1
Gene Alias: AV245725; BCH; BHC; Homeobox protein NK-2 homolog A; homeobox protein Nkx-2.1; NK-2; NK2 homeobox 1; NK-2 homolog A; NKX2; NKX2.1; NKX2-1; NKX2A; NMTC1; RGD1565673; RNA polymerase I termination factor; RNA polymerase I transcription termination factor; T/EBP; TEBP; Thyroid nuclear factor 1; thyroid transcription factor 1; thyroid transcription factor 1-like; thyroid-specific enhancer-binding protein; TITF1; Transcription termination factor 1; transcription termination factor I; transcription termination factor, RNA polymerase I; TTF1; TTF-1; TTF-I
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7270
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q15361
Gene Symbols: Ttf1
Immunogen: Recombinant protein encompassing a sequence within the center region of human Transcription Termination Factor 1. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TTF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ttf1
Gene Alias:
AV245725; BCH; BHC; Homeobox protein NK-2 homolog A; homeobox protein Nkx-2.1; NK-2; NK2 homeobox 1; NK-2 homolog A; NKX2; NKX2.1; NKX2-1; NKX2A; NMTC1; RGD1565673; RNA polymerase I termination factor; RNA polymerase I transcription termination factor; T/EBP; TEBP; Thyroid nuclear factor 1; thyroid transcription factor 1; thyroid transcription factor 1-like; thyroid-specific enhancer-binding protein; TITF1; Transcription termination factor 1; transcription termination factor I; transcription termination factor, RNA polymerase I; TTF1; TTF-1; TTF-I
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7270
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q15361
Gene Symbols:
Ttf1
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Transcription Termination Factor 1. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TWIST1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TWIST1
Gene Alias: AA960487; ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska<m10Jus>; Ska<sup>m10Jus</sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist family bHLH transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist1; twist-related protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7291
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q15672
Gene Symbols: TWIST1
Immunogen: Recombinant protein encompassing a sequence within the center region of human Twist1. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TWIST1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TWIST1
Gene Alias:
AA960487; ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska<m10Jus>; Ska<sup>m10Jus</sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist family bHLH transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist1; twist-related protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7291
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q15672
Gene Symbols:
TWIST1
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Twist1. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Twist1/Twist2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TWIST1
Gene Alias: AA960487; ACS3; AMS; BBRSAY; B-HLH DNA binding protein; bHLHa38; BHLHA39; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; Class A basic helix-loop-helix protein 39; CRS; CRS1; CSO; dermis expressed 1; dermis-expressed protein 1; DERMO1; Dermo-1; dermo-1 protein; FFDD3; H-twist; MGC117334; M-Twist; Pde; pdt; Pluridigite; polydactyly EMS; SCS; SETLSS; Ska<m10Jus>; Ska<sup>m10Jus</sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist basic helix-loop-helix transcription factor 2; twist family bHLH transcription factor 1; twist family bHLH transcription factor 2; twist gene homolog 1; twist homolog 1; twist homolog 2; TWIST homolog of drosophila; Twist1; Twist2; twist-related bHLH protein Dermo1; twist-related protein 1; Twist-related protein 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 117581, 13345, 22160, 59327, 7291, 85489
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.67 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: P26687, P97831, Q15672, Q8WVJ9, Q9D030
Gene Symbols: TWIST1, TWIST2
Immunogen: Recombinant protein encompassing a sequence within the center region of human Twist1/2. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Drosophila, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Twist1/Twist2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TWIST1
Gene Alias:
AA960487; ACS3; AMS; BBRSAY; B-HLH DNA binding protein; bHLHa38; BHLHA39; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; Class A basic helix-loop-helix protein 39; CRS; CRS1; CSO; dermis expressed 1; dermis-expressed protein 1; DERMO1; Dermo-1; dermo-1 protein; FFDD3; H-twist; MGC117334; M-Twist; Pde; pdt; Pluridigite; polydactyly EMS; SCS; SETLSS; Ska<m10Jus>; Ska<sup>m10Jus</sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist basic helix-loop-helix transcription factor 2; twist family bHLH transcription factor 1; twist family bHLH transcription factor 2; twist gene homolog 1; twist homolog 1; twist homolog 2; TWIST homolog of drosophila; Twist1; Twist2; twist-related bHLH protein Dermo1; twist-related protein 1; Twist-related protein 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
117581, 13345, 22160, 59327, 7291, 85489
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.67 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
P26687, P97831, Q15672, Q8WVJ9, Q9D030
Gene Symbols:
TWIST1, TWIST2
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Twist1/2. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Drosophila, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG