PIPA578232

XBP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA578232-Each-of-1 In Stock ₹ 47,015.22

PIPA578232 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

XBP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Xbp1

Gene Alias

D11Ertd39e; Hepatocarcinogenesis-related transcription factor; HTF; OTTHUMP00000028682; Tax-responsive element-binding protein 5; tax-responsive element-binding protein 5 homolog; TREB5; TREB-5; X-box binding protein 1; X-box-binding protein 1; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; XBP1; XBP-1; XBP2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7494

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

2.2 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P17861

Gene Symbols

Xbp1

Immunogen

Recombinant protein encompassing a sequence within the center region of Human XBP1. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Positive Control: HepG2, HepG2 (3μM Thapsigargin treatment for 12 hr) Predicted Reactivity: Mouse (80%), Rat (82%), Pig (88%), Rhesus Monkey (97%), Bovine (90%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • XBP1 encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box
  • This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter
  • It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator
  • It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1)
  • The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor
  • The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress
  • A pseudogene of XBP1 has been identified and localized to chromosome 5.

Compare Similar Items

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Img

Thermo Scientific

PIPA578232

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Antigen:
XBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Xbp1

Gene Alias:
D11Ertd39e; Hepatocarcinogenesis-related transcription factor; HTF; OTTHUMP00000028682; Tax-responsive element-binding protein 5; tax-responsive element-binding protein 5 homolog; TREB5; TREB-5; X-box binding protein 1; X-box-binding protein 1; X-box-binding protein 1, cytoplasmic form; X-box-binding protein 1, luminal form; XBP1; XBP-1; XBP2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7494

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.2 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P17861

Gene Symbols:
Xbp1

Immunogen:
Recombinant protein encompassing a sequence within the center region of Human XBP1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578234

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Antigen:
ZFX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZFX

Gene Alias:
RGD1562664; X-linked zinc finger protein; Zfx; Zfx5; Zfx5,6; Zfx6; zinc finger protein X-linked; zinc finger protein X-linked 5; zinc finger protein X-linked 6; zinc finger protein, X-linked; zinc finger X-chromosomal protein; ZNF926

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7543

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
2.55 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P17010

Gene Symbols:
ZFX

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus of human ZFX. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578235

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Antigen:
ZIC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZIC1

Gene Alias:
CRS6; odd-paired homolog; ZIC; Zic family member 1; Zic family member 1 (odd-paired homolog, Drosophila); zic protein member 1; ZIC1; Zinc finger protein 201; Zinc finger protein of the cerebellum 1; Zinc finger protein ZIC 1; ZNF201

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7545

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.2 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q15915

Gene Symbols:
ZIC1

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ZIC1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578236

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Antigen:
Zyxin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZYX

Gene Alias:
9530098H06Rik; ESP-2; HED-2; LOW QUALITY PROTEIN: zyxin; R75157; ZYX; Zyxin; zyxin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7791

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.46 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q15942

Gene Symbols:
ZYX

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Zyxin. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG