PIPA578243
SHOC2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578243-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA578243 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
SHOC2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Shoc2
Gene Alias
AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
56392, 8036
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.38 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
O88520, Q9UQ13
Gene Symbols
Shoc2
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human SHOC2. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- Positive Control: A431 Predicted Reactivity: Rat (100%), Zebrafish (97%), Xenopus laevis (100%), Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SHOC2 protein participates in protein binding / transferase activity in the fibroblast growth factor receptor signaling pathway and Ras protein signal transduction
- It is a widely expressed protein composed almost entirely of leucine-rich repeats (LRR), with a lysine-rich sequence at the amino terminus and cytoplasmically localized
- SHOC2 acts as a positive modulator of the RAS-MAPK signaling cascade, which is elicited by EGL-15 and LET-23 and mediated by LET-60
- SHOC2 together with protein phosphatase 1c (PP1c) forms a highly specific M-Ras effector complex and is essential for activation of the MAPK pathway by growth factors
- Furthermore, in tumor cells with Ras gene mutations, inhibition of SHOC2 expression inhibits MAPK, but not PI3K activity
- The SHOC2-PP1c holoenzyme provides an attractive therapeutic target for inhibition of the MAPK pathway in cancer
- Recent studies show that aberrantly acquired N-myristoylation of SHOC2 causes human disease Noonan-like syndrome with loose anagen hair.
Compare Similar Items
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Antigen: SHOC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Shoc2
Gene Alias: AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56392, 8036
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.38 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: O88520, Q9UQ13
Gene Symbols: Shoc2
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human SHOC2. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SHOC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Shoc2
Gene Alias:
AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56392, 8036
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.38 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
O88520, Q9UQ13
Gene Symbols:
Shoc2
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human SHOC2. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NPRL3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPRL3
Gene Alias: -14 gene protein; Aag; alpha-globin regulatory element-containing gene protein; alphaRE-14; C16orf35; CGTHBA; conserved gene telomeric to alpha globin cluster; GATOR complex protein NPRL3; HS-26; HS40; HS-40; MARE; nitrogen permease regulator 3-like protein; NPR3; NPR3 like, GATOR1 complex subunit; NPR3-like; NPR3-like, GATOR1 complex subunit; NPRL3; Phg; Protein CGTHBA; Prox1; RMD11; RP23-177M10.6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8131
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.55 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q12980
Gene Symbols: NPRL3
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human NPRL3. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NPRL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPRL3
Gene Alias:
-14 gene protein; Aag; alpha-globin regulatory element-containing gene protein; alphaRE-14; C16orf35; CGTHBA; conserved gene telomeric to alpha globin cluster; GATOR complex protein NPRL3; HS-26; HS40; HS-40; MARE; nitrogen permease regulator 3-like protein; NPR3; NPR3 like, GATOR1 complex subunit; NPR3-like; NPR3-like, GATOR1 complex subunit; NPRL3; Phg; Protein CGTHBA; Prox1; RMD11; RP23-177M10.6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8131
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.55 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q12980
Gene Symbols:
NPRL3
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human NPRL3. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NPRL3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPRL3
Gene Alias: -14 gene protein; Aag; alpha-globin regulatory element-containing gene protein; alphaRE-14; C16orf35; CGTHBA; conserved gene telomeric to alpha globin cluster; GATOR complex protein NPRL3; HS-26; HS40; HS-40; MARE; nitrogen permease regulator 3-like protein; NPR3; NPR3 like, GATOR1 complex subunit; NPR3-like; NPR3-like, GATOR1 complex subunit; NPRL3; Phg; Protein CGTHBA; Prox1; RMD11; RP23-177M10.6
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8131
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 2.34 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q12980
Gene Symbols: NPRL3
Immunogen: Recombinant protein encompassing a sequence within the center region of human NPRL3. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NPRL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPRL3
Gene Alias:
-14 gene protein; Aag; alpha-globin regulatory element-containing gene protein; alphaRE-14; C16orf35; CGTHBA; conserved gene telomeric to alpha globin cluster; GATOR complex protein NPRL3; HS-26; HS40; HS-40; MARE; nitrogen permease regulator 3-like protein; NPR3; NPR3 like, GATOR1 complex subunit; NPR3-like; NPR3-like, GATOR1 complex subunit; NPRL3; Phg; Protein CGTHBA; Prox1; RMD11; RP23-177M10.6
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8131
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
2.34 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q12980
Gene Symbols:
NPRL3
Immunogen:
Recombinant protein encompassing a sequence within the center region of human NPRL3. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TRRAP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TRRAP
Gene Alias: 350/400 kDa PCAF-associated factor; AI481500; OTTHUMP00000197294; OTTHUMP00000197295; PAF350/400; PAF400; STAF40; Tra1; Tra1 homolog; transactivation/transformation-domain associated protein; transformation/transcription domain associated protein; transformation/transcription domain-associated protein; TR-AP; TRRAP
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8295
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ChIP Assay, Immunoprecipitation, Western Blot
Concentration: 1.0 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q9Y4A5
Gene Symbols: TRRAP
Immunogen: Recombinant protein encompassing a sequence within the center region of human TRRAP. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TRRAP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TRRAP
Gene Alias:
350/400 kDa PCAF-associated factor; AI481500; OTTHUMP00000197294; OTTHUMP00000197295; PAF350/400; PAF400; STAF40; Tra1; Tra1 homolog; transactivation/transformation-domain associated protein; transformation/transcription domain associated protein; transformation/transcription domain-associated protein; TR-AP; TRRAP
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8295
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ChIP Assay, Immunoprecipitation, Western Blot
Concentration:
1.0 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q9Y4A5
Gene Symbols:
TRRAP
Immunogen:
Recombinant protein encompassing a sequence within the center region of human TRRAP. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG