PIPA578252

Cullin 4B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA578252-Each-of-1 In Stock ₹ 47,015.22

PIPA578252 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Cullin 4B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CUL4B

Gene Alias

2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

302502, 72584, 8450

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

A2A432, Q13620

Gene Symbols

CUL4B

Immunogen

Recombinant protein encompassing a sequence within the center region of human Cullin 4b. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Positive Control: 293T, A431, HeLa, HepG2, A375, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2 Predicted reactivity: Mouse (93%), Rat (96%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
  • The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit
  • CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme
  • Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage
  • Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication
  • Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression
  • Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism
  • Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.

Compare Similar Items

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Img

Thermo Scientific

PIPA578252

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Antigen:
Cullin 4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CUL4B

Gene Alias:
2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
302502, 72584, 8450

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
A2A432, Q13620

Gene Symbols:
CUL4B

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Cullin 4b. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578253

--


Antigen:
SMARCA5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMARCA5

Gene Alias:
4933427E24Rik; D030040M08Rik; D330027N15Rik; hISWI; hSNF2H; ISWI; MommeD4; mSnf2h; SMARCA5; SNF2H; sucrose nonfermenting protein 2 homolog; sucrose nonfermenting-like 5; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; WCRF135

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
307766, 8467

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.28 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O60264

Gene Symbols:
SMARCA5

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human SNF2H. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578254

--


Antigen:
LMO4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LMO4

Gene Alias:
A730077C12Rik; Breast tumor autoantigen; Crp3; ethanol induced 4; Etohi4; LIM domain only 4; LIM domain only protein 4; LIM domain transcription factor LMO4; LIM-only 4 protein; LMO4; LMO-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8543

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P61968

Gene Symbols:
LMO4

Immunogen:
Full length human LMO4 Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578255

--


Antigen:
TCAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tcap

Gene Alias:
19 kDa sarcomeric protein; AI503981; AJ223855; CMD1N; CMH25; LGMD2G; limb girdle muscular dystrophy 2G (autosomal recessive); Tcap; T-cap; TELE; telethonin; teneurin C-terminal associated peptide; titin cap protein; titin-cap; titin-cap (telethonin)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21393, 8557

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 0.1M glycine, 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O15273, O70548

Gene Symbols:
Tcap

Immunogen:
Full length human Telethonin Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG