PIPA578531

CHFR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA578531-Each-of-1 In Stock ₹ 47,015.22

PIPA578531 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

CHFR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chfr

Gene Alias

5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

55743

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q96EP1

Gene Symbols

Chfr

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human CHFR. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Predicted Reactivity: Bovine (80%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons
  • Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus
  • Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome
  • Promotes the ubiquitination and subsequent degradation of AURKA and PLK1
  • Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation
  • May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer
  • Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA578531

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Antigen:
CHFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chfr

Gene Alias:
5730484M20Rik; C230082M18; checkpoint with forkhead and ring finger domains; Checkpoint with forkhead and RING finger domains protein; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; Chfr; E3 ubiquitin-protein ligase CHFR; fc43f10; FLJ10796; FLJ33629; RING finger protein 196; RING-type E3 ubiquitin transferase CHFR; RNF116; RNF196; si:dkey-69h6.7; wu:fc43f10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55743

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q96EP1

Gene Symbols:
Chfr

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human CHFR. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578532

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Antigen:
CCAR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCAR1

Gene Alias:
2610511G16Rik; 9430036H15Rik; Carp1; CARP-1; Ccar1; Cell cycle and apoptosis regulatory protein 1; cell division cycle and apoptosis regulator 1; cell division cycle and apoptosis regulator protein 1; Death inducer with SAP domain; DIS; MGC44628; OTTHUMP00000019709; RGD1560358; RP11-437A18.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55749, 67500

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8CH18, Q8IX12

Gene Symbols:
CCAR1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human CCAR1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578533

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Antigen:
MBD5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MBD5

Gene Alias:
9430004D19Rik; AA536666; AI426407; C030040A15Rik; FLJ11113; FLJ30517; Gm1630; KIAA1461; MBD5; methyl-CpG binding domain protein 5; methyl-CpG-binding domain protein 5; Methyl-CpG-binding protein MBD5; MRD1; OTTMUSG00000012483

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55777

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
2.19 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q9P267

Gene Symbols:
MBD5

Immunogen:
Recombinant protein encompassing a sequence within the center region of human MBD5. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578534

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Antigen:
DCP1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dcp1a

Gene Alias:
1110066A22Rik; 4930568L04Rik; AU019772; D14Ertd817e; DCP1 decapping enzyme homolog A; DCP1 decapping enzyme homolog A (S. cerevisiae); DCP1 decapping enzyme-like protein A; DCP1A; decapping enzyme; decapping enzyme hDcp1a; decapping mRNA 1A; FLJ21691; HSA275986; MAD homolog 4 interacting transcription coactivator 1; MAD homolog 4-interacting transcription coactivator 1; Mitc1; mRNA-decapping enzyme 1A; Nbla00360; putative protein product of Nbla00360; RGD1561298; Smad4-interacting transcriptional co-activator; SMAD4IP1; SMIF; test2; transcription factor SMIF

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55802

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
1.0 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9NPI6

Gene Symbols:
Dcp1a

Immunogen:
Recombinant protein encompassing a sequence within the center region of human DCP1A. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG