SHANK3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578548-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA578548 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
SHANK3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Shank3
Gene Alias
AI841104; DEL22q13.3; Kiaa1650; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2; PROSAP2; PSAP2; SCZD15; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat domains-like protein 3 variant 2; SH3 and multiple ankyrin repeat domains-like protein 3 variant 3; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-3; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-2; SH3/ankyrin domain gene 3; shank postsynaptic density protein; Shank postsynaptic density protein 3a; SHANK3; shank3 splice variant II; shank3 splice variant III; shank3 splice variant IV; Shank3b; SHANK3c-3; SHANK3c-4; shank3e splice variant III; shank3e splice variant IV; SPANK 2; SPANK2; SPANK-2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
58234, 59312
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.67 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q4ACU6, Q9JLU4
Gene Symbols
Shank3
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of Mouse SHANK3. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: mouse brain, rat brain Predicted Reactivity: Human (99%) Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SHANK3 is a major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance
- It interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton
- SHANK3 plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters
- By way of this control of actin dynamics, SHANK3 participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling
- It also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity
- SHANK3 may be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation
- (Uniprot)
Compare Similar Items
Show Difference
Antigen: SHANK3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Shank3
Gene Alias: AI841104; DEL22q13.3; Kiaa1650; proline rich synapse associated protein 2; proline-rich synapse-associated protein 2; PROSAP2; PSAP2; SCZD15; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat domains-like protein 3 variant 2; SH3 and multiple ankyrin repeat domains-like protein 3 variant 3; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant c-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-2; SH3 and multiple ankyrin repeat domains-like protein 3 variant d-3; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-1; SH3 and multiple ankyrin repeat domains-like protein 3 variant e-2; SH3/ankyrin domain gene 3; shank postsynaptic density protein; Shank postsynaptic density protein 3a; SHANK3; shank3 splice variant II; shank3 splice variant III; shank3 splice variant IV; Shank3b; SHANK3c-3; SHANK3c-4; shank3e splice variant III; shank3e splice variant IV; SPANK 2; SPANK2; SPANK-2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 58234, 59312
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.67 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q4ACU6, Q9JLU4
Gene Symbols: Shank3
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of Mouse SHANK3. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: SELK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SELENOK
Gene Alias: 1110001C03Rik; AA673253; heat shock protein; heat shock protein, 30 kDa; Hsp30; HSPC030; HSPC297; Selenok; Selenoprotein K; SELK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 58515
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.62 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q9Y6D0
Gene Symbols: SELENOK
Immunogen: Recombinant protein encompassing a sequence within the center region of human SELK. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: PEX5L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PEX5L
Gene Alias: 1700016J08Rik; HCN channel auxiliary subunit; peroxin 2; peroxin-5-related protein; peroxisomal biogenesis factor 5 like; peroxisomal biogenesis factor 5-like; peroxisomal targeting signal 1 receptor-like; peroxisome biogenesis factor 5-like; Pex2; PEX2-related protein; Pex5l; PEX5-like protein; Pex5p-related protein; Pex5r; PEX5-related protein; PEX5RP; PXR2; PXR2B; Tetratricopeptide repeat-containing Rab8b-interacting protein; TPR-containing Rab8b-interacting protein; Trip8b; Trjip8b
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 286937, 58869
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.49 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q8C437, Q925N3
Gene Symbols: PEX5L
Immunogen: Recombinant protein encompassing a sequence within the center region of mouse PEX5L. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
