PIPA578661
IL-27 p28 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA578661-Each-of-1 | In Stock | ₹ 47,271.90 |
PIPA578661 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,271.90
GST (18%): ₹ 8,508.942
Total Price: ₹ 55,780.842
Antigen
IL-27 p28
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Il27
Gene Alias
IL27; IL-27; IL-27 p28 subunit; IL-27 subunit alpha; Il27a; IL-27A; IL-27-A; IL27-A; IL27p28; IL-27p28; IL30; IL-30; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27; interleukin-27 subunit alpha; Interleukin-30; p28
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
246778
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.65 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q8NEV9
Gene Symbols
Il27
Immunogen
Recombinant protein encompassing a sequence within the center region of human IL27. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: 3XFlag-human IL-27 -transfected 293T Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- IL-27, a member of the IL-12 family, is a heterodimeric protein consisting of the p40-related protein Epstein-Barr virus-induced gene 3 (EBI3) non-covalently linked to an IL-12p35-related protein, p28 (also known as IL-30)
- IL-27 is produced by activated APCs and mature dendritic cells
- IL-27 exerts its activities on NK cells and naive CD4+ T cells; mRNA expression analysis of IL-27 receptor components (WSX-1/TCCR and gp130) suggests that IL-27 may also target other cells, including mast cells and monocytes
- Binding of IL-27 to WSX-1/gp130 activates JAK1, STAT1, and STAT3 and STAT1/3 phosphorylation
- WSX-1/TCCR-deficient mice develop impaired Th1 responses and are more susceptible to infection with L
- monocytogenes suggesting that Th1 responses require IL-27
- Although activation of WSX-1 is required for the initiation of Th1 responses, it is not necessary for maintaining Th1 responses
- IL-27 alone is not able to induce the differentiation of CD4+ T cells into IFN-γ-producing cells, suggesting a role for IL-27 as an initial activator of Th1 responses
- An important effect of IL-27 in initiating Th1 responses is the induction of the Th1-specific transcription factor T-bet as well as the suppression of the Th2-specific transcription factor GATA-3
- T-bet plays a critical role in Th1 differentiation by its ability to maintain IL-12Rβ2 expression following CD4+ T cell activation
- Recent studies indicate that IL-27 has a potent antitumor activity
- In vitro, IL-27 has been found to act directly on naive CD8 cells, generating CTL with enhanced granzyme B expression
- In vivo, IL-27 has been reported to augment CTL activity, inhibit tumor growth, and induce complete regression of primary and metastatic neuroblastoma tumors.
Compare Similar Items
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Antigen: IL-27 p28
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Il27
Gene Alias: IL27; IL-27; IL-27 p28 subunit; IL-27 subunit alpha; Il27a; IL-27A; IL-27-A; IL27-A; IL27p28; IL-27p28; IL30; IL-30; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27; interleukin-27 subunit alpha; Interleukin-30; p28
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 246778
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.65 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q8NEV9
Gene Symbols: Il27
Immunogen: Recombinant protein encompassing a sequence within the center region of human IL27. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IL-27 p28
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Il27
Gene Alias:
IL27; IL-27; IL-27 p28 subunit; IL-27 subunit alpha; Il27a; IL-27A; IL-27-A; IL27-A; IL27p28; IL-27p28; IL30; IL-30; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27; interleukin-27 subunit alpha; Interleukin-30; p28
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
246778
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.65 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q8NEV9
Gene Symbols:
Il27
Immunogen:
Recombinant protein encompassing a sequence within the center region of human IL27. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NEIL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEIL2
Gene Alias: DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease 8-like 2; endonuclease VIII-like 2; Gm1212; NEH2; nei endonuclease VIII-like 2; nei endonuclease VIII-like 2 (E. coli); nei homolog 2; nei like 2; nei like 2 (E. coli); nei like DNA glycosylase 2; NEI2; Neil2; nei-like DNA glycosylase 2; nei-like protein 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 252969
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.88 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q969S2
Gene Symbols: NEIL2
Immunogen: Recombinant protein encompassing a sequence within the center region of human NEIL2. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NEIL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEIL2
Gene Alias:
DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease 8-like 2; endonuclease VIII-like 2; Gm1212; NEH2; nei endonuclease VIII-like 2; nei endonuclease VIII-like 2 (E. coli); nei homolog 2; nei like 2; nei like 2 (E. coli); nei like DNA glycosylase 2; NEI2; Neil2; nei-like DNA glycosylase 2; nei-like protein 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
252969
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.88 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q969S2
Gene Symbols:
NEIL2
Immunogen:
Recombinant protein encompassing a sequence within the center region of human NEIL2. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PCSK9
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PCSK9
Gene Alias: AI415265; AI747682; convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia; LDLCQ1; NARC1; NARC-1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; PCSK9; Proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin-like protease PC9
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 255738
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ELISA, Flow Cytometry, Western Blot
Concentration: 1.0 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q8NBP7
Gene Symbols: PCSK9
Immunogen: Recombinant protein encompassing a sequence within the center region of human PCSK9. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PCSK9
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PCSK9
Gene Alias:
AI415265; AI747682; convertase subtilisin; convertase subtilisin/kexin type 9 preproprotein; FH3; HCHOLA3; hypercholesterolemia; LDLCQ1; NARC1; NARC-1; neural apoptosis regulated convertase 1; neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; PCSK9; Proprotein convertase 9; proprotein convertase PC9; proprotein convertase subtilisin/kexin type 9; PSEC0052; Subtilisin/kexin-like protease PC9
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
255738
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Western Blot
Concentration:
1.0 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q8NBP7
Gene Symbols:
PCSK9
Immunogen:
Recombinant protein encompassing a sequence within the center region of human PCSK9. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PTF1A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTF1A
Gene Alias: bHLH transcription factor; bHLH transcription factor p48; BHLHA29; class A basic helix-loop-helix protein 29; class II bHLH protein PTF1A; exocrine pancreas-specific transcription factor p48; p48 DNA-binding subunit of transcription factor PTF1; PACA; PAGEN2; pancreas associated transcription factor 1a; pancreas specific transcription factor, 1a; pancreas transcription factor 1 subunit alpha; pancreas transcription factor1 p48 subunit; pancreas-specific transcription factor 1a; PTF1; PTF1A; PTF1p48; PTF1-p48; Ptfa; si:zc142h2.2; zgc:112216
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 256297
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q7RTS3
Gene Symbols: PTF1A
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human PTF1A. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PTF1A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTF1A
Gene Alias:
bHLH transcription factor; bHLH transcription factor p48; BHLHA29; class A basic helix-loop-helix protein 29; class II bHLH protein PTF1A; exocrine pancreas-specific transcription factor p48; p48 DNA-binding subunit of transcription factor PTF1; PACA; PAGEN2; pancreas associated transcription factor 1a; pancreas specific transcription factor, 1a; pancreas transcription factor 1 subunit alpha; pancreas transcription factor1 p48 subunit; pancreas-specific transcription factor 1a; PTF1; PTF1A; PTF1p48; PTF1-p48; Ptfa; si:zc142h2.2; zgc:112216
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
256297
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q7RTS3
Gene Symbols:
PTF1A
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human PTF1A. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG