PIPA578799

Apolipoprotein B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578799-Each-of-1 In Stock ₹ 40,854.90

PIPA578799 - Each of 1

₹ 40,854.90

In Stock

Quantity

1

Base Price: ₹ 40,854.90

GST (18%): ₹ 7,353.882

Total Price: ₹ 48,208.782

Antigen

Apolipoprotein B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APOB

Gene Alias

Aa1064; Ac1-060; AI315052; Apo B100; Apo B-100; Apo B-48; APOB; apo-B; ApoB 100; ApoB 48; ApoB-100; apob-48; apolipo b; apolipoprotein B; apolipoprotein B (including Ag(x) antigen); Apolipoprotein B 100; Apolipoprotein B 48; apolipoprotein B PI; Apolipoprotein B100; apolipoprotein B-100; apolipoprotein B46; apolipoprotein B47; apolipoprotein B48; Apolipoprotein B-48; apolipoprotein B49; FLDB; LDLCQ4; LOX-1; mCG_129875; MGC176318; Ox-LDL receptor 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

338

Content And Storage

-20°C

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

P04114

Gene Symbols

APOB

Immunogen

E. coli-derived human Apolipoprotein B recombinant protein (Position: Q246-N450).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Apolipoprotein B (apo B) in human plasma is a major protein of low density lipoproteins (LDL) with a molecular mass of approximately 260-500 kDa
  • Apolipoprotein B binds to specific receptors on cell membranes and is involved in removal of LDL and very low density lipoprotein (VLDL) cholesterol from circulation
  • Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood
  • LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearance of cholesterol from the circulation
  • In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36
  • Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described
  • MDA-oxidized LDL appear to be different from LDL oxidized by other means
  • Apolipoprotein B is mostly synthesized in the liver, and is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a)
  • Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis
  • Normal plasma apolipoprotein B levels are around 800mg/L
  • Apolipoprotein B occurs in plasma as two main isoforms, apoB-48 and apoB-100
  • The intestinal and the hepatic forms of Apolipoprotein B are encoded by a single gene from a single, very long mRNA
  • The two isoforms share a common N-terminal sequence
  • The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination
  • Mutations in the Apolipoprotein B gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective Apolipoprotein B, diseases affecting plasma cholesterol and Apolipoprotein B levels.

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PIPA578799

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Antigen:
Apolipoprotein B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOB

Gene Alias:
Aa1064; Ac1-060; AI315052; Apo B100; Apo B-100; Apo B-48; APOB; apo-B; ApoB 100; ApoB 48; ApoB-100; apob-48; apolipo b; apolipoprotein B; apolipoprotein B (including Ag(x) antigen); Apolipoprotein B 100; Apolipoprotein B 48; apolipoprotein B PI; Apolipoprotein B100; apolipoprotein B-100; apolipoprotein B46; apolipoprotein B47; apolipoprotein B48; Apolipoprotein B-48; apolipoprotein B49; FLDB; LDLCQ4; LOX-1; mCG_129875; MGC176318; Ox-LDL receptor 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
338

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P04114

Gene Symbols:
APOB

Immunogen:
E. coli-derived human Apolipoprotein B recombinant protein (Position: Q246-N450).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA578801

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Antigen:
APOBEC3G

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOBEC3G

Gene Alias:
A3G; APOBEC3G; APOBEC-related cytidine deaminase; APOBEC-related protein; APOBEC-related protein 9; apolipoprotein B editing enzyme catalytic polypeptide-like 3G; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3G; apolipoprotein B mRNA editing enzyme catalytic subunit 3G; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G; apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3G; ARCD; ARP9; ARP-9; ASGPR2; ASGP-R2; bK150C2.7; CEM15; CEM-15; CLEC4H2; Deoxycytidine deaminase; dJ494G10.1; DNA dC->dU editing enzyme; DNA dC->dU-editing enzyme APOBEC-3G; FLJ12740; HBXBP; HL-2; MDS019; OTTHUMP00000028911; phorbolin-like protein MDS019

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
60489

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q9HC16

Gene Symbols:
APOBEC3G

Immunogen:
E.coli-derived human APOBEC3G recombinant protein (Position: E191-N384).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA578802

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Antigen:
ApoC3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOC3

Gene Alias:
Apoc3; APOCIII; Apo-CIII; apoC-III; Apolipoprotein; Apolipoprotein C3; apolipoprotein C-3; apolipoprotein C-III; HALP2; MGC150353

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11814, 24207, 345

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P02656, P06759, P33622

Gene Symbols:
APOC3

Immunogen:
E. coli-derived human Apolipoprotein CIII recombinant protein (Position: S21-A99).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA578803

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Antigen:
APOE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOE

Gene Alias:
AD2; AI255918; APOE; apo-E; ApoE4; APOEA; Apolipoprotein; apolipoprotein E; apolipoprotein E3; apolipoprotein E4; Apoprotein; B2G1; BG; LDLCQ5; LPG; MGC1571

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11816, 25728

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P02650, P08226

Gene Symbols:
APOE

Immunogen:
E.coli-derived mouse Apolipoprotein E recombinant protein (Position: D55-Q294).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG