PIPA579148

RIG-I Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579148-Each-of-1 In Stock ₹ 41,796.06

PIPA579148 - Each of 1

₹ 41,796.06

In Stock

Quantity

1

Base Price: ₹ 41,796.06

GST (18%): ₹ 7,523.291

Total Price: ₹ 49,319.351

Antigen

RIG-I

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DDX58

Gene Alias

6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

230073, 23586, 297989

Content And Storage

-20°C

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

O95786, Q6Q899

Gene Symbols

DDX58

Immunogen

E. coli-derived human DDX58 recombinant protein (Position: H871-K925).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Retinoic acid-inducible gene I, RIG-I is a pattern recognition receptor (PRR) involved in the recognition of viral dsRNA
  • Along with MDA5, RIG-I detects viral dsRNA and activates the innate immune response
  • Both MDA5 and RIG-I are RNA helicases and they perform overlapping as well as distinct roles
  • RIG-I is activated by dsRNAs without a 5'-triphosphate end and short dsRNAs, whereas MDA5 is activated by long dsRNAs
  • Once activated, both proteins signal through IPS-1 activating transcription factors NF-kappaB and IRF-3 (1) and μgtimately activating apoptosis, cytokine signaling, and inflammation
  • RIG-I is essential for signaling by influenza A, influenza B, human respiratory syncytial virus (3), paromyxoviruses, Japanese encephalitis virus, and West Nile virus
  • MicroRNA-146a has been implicated in feedback inhibition of RIG-I-dependant antiviral response by negatively regulating RIG-I targets TRAF6, IRAK1, and IRAK2
  • Recent evidence has implicated RIG-I in the detection of cytosolic DNA through RNA polymerase III activity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA579148

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Antigen:
RIG-I

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DDX58

Gene Alias:
6430573D20Rik; C330021E21; Ddx58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DEAD/H box polypeptide RIG-I; DEAD-box protein 58; DEXD/H-box helicase 58; probable ATP-dependent RNA helicase DDX58; Retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein; retinoic acid-inducible gene-I; RIG-1; RIGI; RIG-I; RIG-I-like receptor 1; RLR-1; RNA helicase RIG-I; SGMRT2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
230073, 23586, 297989

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
O95786, Q6Q899

Gene Symbols:
DDX58

Immunogen:
E. coli-derived human DDX58 recombinant protein (Position: H871-K925).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579151

--


Antigen:
DGCR8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DGCR8

Gene Alias:
C22orf12; D16H22S1742E; D16H22S788E; D16Wis2; DGCR8; DGCR8 microprocessor complex subunit; DGCR8, microprocessor complex subunit; DGCRK6; DiGeorge syndrome critical region 8; diGeorge syndrome critical region 8 homolog; DiGeorge syndrome critical region gene 8; Gy1; LP4941; Microprocessor complex subunit DGCR8; mir-1306; N41; pasha; sb:eu827; sb:eu832; si:ch211-106a19.4; Vo59c07; wu:fc23f08; wu:fc38f06

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287954, 54487, 94223

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q8WYQ5, Q9EQM6

Gene Symbols:
DGCR8

Immunogen:
E. coli-derived human DGCR8 recombinant protein (Position: K561-Q762).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579152

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Antigen:
DHFR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DHFR

Gene Alias:
8430436I03Rik; AA607882; AI662710; AW555094; Dhfr; Dhfr1; DHFRP1; Dihydrofolate reductase; Dihydrofolate reductase 1 (active); DYR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13361, 1719, 24312

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P00374, P00375, Q920D2

Gene Symbols:
DHFR

Immunogen:
E.coli-derived human DHFR recombinant protein (Position: V2-D187).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579155

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Antigen:
DKK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DKK2

Gene Alias:
dickkopf 2; dickkopf 2 homolog; Dickkopf gene 2; dickkopf homolog 1; dickkopf homolog 2; dickkopf homolog 2 (Xenopus laevis); dickkopf homolog 4; dickkopf related protein-2; dickkopf WNT signaling pathway inhibitor 2; dickkopf-2; Dickkopf-related protein 2; DKK2; DKK-2; Dkk4; hDkk-2; mDkk-2; UNQ682/PRO1316

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27123, 295445

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q9UBU2

Gene Symbols:
DKK2

Immunogen:
E.coli-derived human DKK2 recombinant protein (Position: K34-I259).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG