PIPA579370

HLA-DQB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579370-Each-of-1 In Stock ₹ 38,844.24

PIPA579370 - Each of 1

₹ 38,844.24

In Stock

Quantity

1

Base Price: ₹ 38,844.24

GST (18%): ₹ 6,991.963

Total Price: ₹ 45,836.203

Antigen

HLA-DQB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-DQB1

Gene Alias

CELIAC1; DQ beta 1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3119

Content And Storage

-20°C

Form

Lyophilized

Applications

Immunocytochemistry, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

P01920

Gene Symbols

HLA-DQB1

Immunogen

A synthetic peptide corresponding to a sequence of human HLA-DQB1 (DAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • HLA-DRB1 belongs to the HLA class II beta chain paralogs
  • The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane
  • It plays a central role in the immune system by presenting peptides derived from extracellular proteins
  • Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
  • The beta chain is approximately 26-28 kDa
  • It is encoded by 6 exons
  • Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail
  • Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
  • Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5
  • DRB1 is present in all individuals
  • Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5
  • There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA579370

--


Antigen:
HLA-DQB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DQB1

Gene Alias:
CELIAC1; DQ beta 1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3119

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P01920

Gene Symbols:
HLA-DQB1

Immunogen:
A synthetic peptide corresponding to a sequence of human HLA-DQB1 (DAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579372

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Antigen:
HMBS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hmbs

Gene Alias:
alternative name: porphobilinogen deaminase; HEM3; hemC; HMBS; Hydroxymethylbilane synthase; PBG D; PBGD; PBG-D; PORC; Porphobilinogen deaminase; porphyria, acute; Chester type; pre-uroporphyrinogen synthase; similar to Porphobilinogen deaminase (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (PBG-D); T25658; Ups; uroporphyrinogen I synthase; uroporphyrinogen I synthetase; URO-S; Uros1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15288, 25709, 3145

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P08397, P19356, P22907

Gene Symbols:
Hmbs

Immunogen:
E. coli-derived human HMBS recombinant protein (Position: N6-H361).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579374

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Antigen:
HMG4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HMGB3

Gene Alias:
high mobility group box 3; high mobility group protein 1; high mobility group protein 2a; High mobility group protein 4; high mobility group protein B1; high mobility group protein B3; high mobilty group protein 2A; high-mobility group (nonhistone chromosomal) protein 4; high-mobility group protein 4; HMG-1; HMG2a; HMG-2a; HMG4; HMG-4; HMGB1; Hmgb3; HMGB3 transcript variant 1/2; MGC90319; RGD1564407; Unknown (protein for MGC:133786)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15354, 305373, 3149

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
O15347, O54879

Gene Symbols:
HMGB3

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human HMG4 (62-95aa EMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKR).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579375

--


Antigen:
HMGB4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HMGB4

Gene Alias:
1700001F22Rik; AI326135; dJ1007G16.5; high mobility group box 4; high mobility group protein B4; high-mobility group box 4; HMG2 like; Hmgb4; LOC539195 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
127540, 685271, 69317

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
Q6P8W9, Q8WW32

Gene Symbols:
HMGB4

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human HMGB4 (24-41aa RNKFKEQQPNTYVGFKEF).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG