PIPA579445

IGF1R (CD221) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA579445-Each-of-1 In Stock ₹ 39,870.96

PIPA579445 - Each of 1

₹ 39,870.96

In Stock

Quantity

1

Base Price: ₹ 39,870.96

GST (18%): ₹ 7,176.773

Total Price: ₹ 47,047.733

Antigen

IGF1R (CD221)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IGF1R

Gene Alias

A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16001, 25718

Content And Storage

-20°C

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

P24062, Q60751

Gene Symbols

IGF1R

Immunogen

E. coli-derived mouse IGF1 Receptor recombinant protein (Position: E31-K257).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2
  • IGFR has been implicated in a variety of cancers
  • The protein is a tetramer consisting of two alpha, and two beta subunits
  • The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2
  • Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136
  • The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.

Compare Similar Items

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Img

Thermo Scientific

PIPA579445

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Antigen:
IGF1R (CD221)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF1R

Gene Alias:
A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16001, 25718

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P24062, Q60751

Gene Symbols:
IGF1R

Immunogen:
E. coli-derived mouse IGF1 Receptor recombinant protein (Position: E31-K257).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579448

--


Antigen:
IGFBP-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP1

Gene Alias:
AFBP; alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP 1; hIGFBP1; hIGFBP-1; IBP 1; IBP1; IBP-1; IGF BP25; IGFBA; IGF-binding protein 1; IGFBP; IGFBP 1; Igfbp1; Igfbp-1; IGF-BP25; Insulin like growth factor binding protein; insulin like growth factor binding protein 1; insulin-like growth factor binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16006, 25685

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P21743, P47876

Gene Symbols:
IGFBP1

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse IGFBP-1 (177-207aa REIADLKKWKEPCQRELYKVLERLAAAQQKA).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579449

--


Antigen:
IGFBP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP2

Gene Alias:
AI255832; BP2; BRL-BP; IBP2; IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP2; IGFBP-2; IGF-BP53; ILGFBPA; Insulin like growth factor binding protein; insulin like growth factor binding protein 2; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; insulin-like growth factor-binding protein 2; mIGFBP-2; OTTHUMP00000207753

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3485

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P18065

Gene Symbols:
IGFBP2

Immunogen:
E. coli-derived human IGFBP2 recombinant protein (Position: A36-Q325).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579450

--


Antigen:
IGFBP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP2

Gene Alias:
AI255832; BP2; BRL-BP; IBP2; IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; IGFBP2; IGFBP-2; IGF-BP53; ILGFBPA; Insulin like growth factor binding protein; insulin like growth factor binding protein 2; insulin-like growth factor binding protein 2; insulin-like growth factor binding protein 2, 36kDa; insulin-like growth factor-binding protein 2; mIGFBP-2; OTTHUMP00000207753

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16008, 25662, 3485

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
P12843, P18065, P47877

Gene Symbols:
IGFBP2

Immunogen:
E. coli-derived rat IGFBP2 recombinant protein (Position: E35-Q304).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG