PIPA579483

IL18BP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579483-Each-of-1 In Stock ₹ 38,844.24

PIPA579483 - Each of 1

₹ 38,844.24

In Stock

Quantity

1

Base Price: ₹ 38,844.24

GST (18%): ₹ 6,991.963

Total Price: ₹ 45,836.203

Antigen

IL18BP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL18BP

Gene Alias

Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16068, 84388

Content And Storage

-20°C

Form

Lyophilized

Applications

ELISA, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

Q9Z0M9

Gene Symbols

IL18BP

Immunogen

E. coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Interleukin-18 binding protein (IL-18BP) is a constitutively secreted glycoprotein that acts as a natural antagonist for interleukin-18 (IL-18) by preventing interaction between IL-18 and its receptors
  • Through this binding, IL-18BP neutralizes the proinflammatory role of IL-18 in cell-mediated immune responses, resulting in reduced IFN-gamma production by T helper type I cells and inhibition of allospecific cytotoxic T lymphocyte (CTL) activity through augmented natural killer (NK) cell cytotoxicity
  • As an inhibitor of IL-18 and an essential component of skin homeostasis, IL-18BP has been linked to a variety of diseases, including eczema, asthma, and the autoimmune condition, Crohn's disease
  • The upregulation of IL-18BP by keratinocytes expressing the human papillomavirus (HPV) E7 oncoprotein has been shown to decrease IL-18-induced IFN-gamma production and IL-18-mediated T cell activation
  • Elevated levels of IL-18 and IL-18BP, as well as proinflammatory cytokines IFN-gamma, TNF-alpha, IL-1beta and IL-8, have been linked to chronic inflammation and observed in macrophages (including Kupffer cells) isolated from lesions and intestinal tissues of Crohn's disease patients
  • As a member of the immunoglobulin-like class of receptors, IL-18BP contains a single immunoglobulin (Ig) domain; although two (b and d) of the four identified human isoforms (a-d) contain incomplete domains that greatly reduce their binding affinity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA579483

--


Antigen:
IL18BP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL18BP

Gene Alias:
Igifbp; Il18bp; IL-18BP; IL18BPa; interferon gamma inducing factor binding protein; interferon gamma-inducing factor-binding protein; interleukin 18 binding protein; interleukin-18 binding protein; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; MC54L; Tadekinig-alfa

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16068, 84388

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q9Z0M9

Gene Symbols:
IL18BP

Immunogen:
E. coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579484

--


Antigen:
IL-1 beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL1B

Gene Alias:
catabolin; cytokine; Hematopoietin 1 (H1); IFN beta inducing factor; il 1b; IL 1β; IL-1; IL1 B; IL-1 beta; IL-1 precursor; IL1B; IL-1B; IL1B1; IL1beta; IL-1beta; IL1-BETA; IL1F2; IL1β; ILN; Interleukin; interleukin 1 beta; Interleukin 1 beta precursor; interleukin 1, beta; interleukin 1, beta 1; interleukin 1-beta; interleukin*1*beta; Interleukin1 beta; interleukin-1 beta; interleukin-1 beta precursor; interleukin-1 beta precursor (AA -113 to 153); interleukin-1 beta proprotein; interleukin-1b; interleukin-1beta; interleukin-beta; LAF; lymphocyte proliferation-potentiating factor; Osteoclast activating factor (OAF); preinterleukin 1 beta; Pro interleukin 1 beta; prointerleukin-1 beta; pro-interleukin-1-beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24494

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
Q63264

Gene Symbols:
IL1B

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of rat IL-1 beta (249-263aa FLGNSNGRDIVDFTM).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579485

--


Antigen:
IL-1 beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL1B

Gene Alias:
catabolin; cytokine; Hematopoietin 1 (H1); IFN beta inducing factor; il 1b; IL 1β; IL-1; IL1 B; IL-1 beta; IL-1 precursor; IL1B; IL-1B; IL1B1; IL1beta; IL-1beta; IL1-BETA; IL1F2; IL1β; ILN; Interleukin; interleukin 1 beta; Interleukin 1 beta precursor; interleukin 1, beta; interleukin 1, beta 1; interleukin 1-beta; interleukin*1*beta; Interleukin1 beta; interleukin-1 beta; interleukin-1 beta precursor; interleukin-1 beta precursor (AA -113 to 153); interleukin-1 beta proprotein; interleukin-1b; interleukin-1beta; interleukin-beta; LAF; lymphocyte proliferation-potentiating factor; Osteoclast activating factor (OAF); preinterleukin 1 beta; Pro interleukin 1 beta; prointerleukin-1 beta; pro-interleukin-1-beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16176, 24494

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P10749, Q63264

Gene Symbols:
IL1B

Immunogen:
E.coli-derived rat IL-1 beta recombinant protein (Position: V117-S268).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579486

--


Antigen:
IL1F10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL1F10

Gene Alias:
family of interleukin 1-theta; FIL1 theta; FIL1T; FIL1-theta; FKSG75; IL-1 theta; Il1f10; IL-1F10; IL-1F10 (canonical form IL-1F10a); IL1HY2; IL-1HY2; IL1-theta; IL38; IL-38; interleukin 1 family member 10 (theta); interleukin 1 family, member 10; interleukin 1 family, member 10 (theta); interleukin 1 family, member 7; interleukin-1 family member 10; Interleukin-1 HY2; interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta; Interleukin-1 theta; Interleukin-38; UNQ6119/PRO20041

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84639

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q8WWZ1

Gene Symbols:
IL1F10

Immunogen:
E. coli-derived human IL1F10 recombinant protein (Position: M1-W152).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG