PIPA579675

MLH1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA579675-Each-of-1 In Stock ₹ 39,785.40

PIPA579675 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

MLH1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mlh1

Gene Alias

1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4292

Content And Storage

-20°C

Form

Lyophilized

Applications

ChIP Assay, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

P40692

Gene Symbols

Mlh1

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human MLH1 (722-756aa KALRSHILPPKHFTEDGNILQLANLPDLYKVFERC).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • MLH1 is a DNA mismatch repair protein
  • The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time
  • An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI)
  • These defects in DNA repair pathways have been related to human carcinogenesis
  • The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC)
  • MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process
  • It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Compare Similar Items

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Thermo Scientific

PIPA579675

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Antigen:
MLH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4292

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ChIP Assay, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P40692

Gene Symbols:
Mlh1

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MLH1 (722-756aa KALRSHILPPKHFTEDGNILQLANLPDLYKVFERC).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579676

--


Antigen:
CD10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mme

Gene Alias:
6030454K05Rik; Atriopeptidase; C85356; CALLA; CD10; CMT2T; common acute lymphoblastic leukemia antigen; common acute lymphocytic leukemia antigen; Enkephalinase; EPN; membrane metallo endopeptidase; membrane metalloendopeptidase; membrane metallo-endopeptidase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; MME; NEP; neprilysin; neprilysin-390; neprilysin-411; neutral endopeptidase 24.11; SFE; Skin fibroblast elastase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24590, 4311

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
P07861, P08473

Gene Symbols:
Mme

Immunogen:
E.coli-derived human CD10 recombinant protein (Position: Y52-W750).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579677

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Antigen:
MMP10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MMP10

Gene Alias:
AV377895; matrix metallo protease; matrix metallopeptidase 10; matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10; matrix metalloproteinase 10 (stromelysin 2); matrix metalloproteinase-10; MMP; Mmp10; MMP-10; MMPs; SL-2; STMY2; stromelysin 2; stromelysin-2; Transformation-associated protein 34A; transin 2; transin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117061, 17384, 4319

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O55123, P07152, P09238

Gene Symbols:
MMP10

Immunogen:
E. coli-derived human MMP10 recombinant protein (Position: Y239-C476).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579678

--


Antigen:
MMP11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mmp11

Gene Alias:
matrix metallo protease; matrix metallopeptidase 11; matrix metallopeptidase 11 (stromelysin 3); Matrix metalloproteinase 11 (stromelysin 3); matrix metalloproteinase-11; MMP; MMP11; MMP-11; MMPs; SL-3; ST3; Stmy3; stromelysin III; stromelysin-3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17385, 25481, 4320

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P24347, Q02853, Q499S5

Gene Symbols:
Mmp11

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human MMP11 (104-135aa RWEKTDLTYRILRFPWQLVQEQVRQTMAEALK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG