PIPA579700

MTCO1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579700-Each-of-1 In Stock ₹ 38,844.24

PIPA579700 - Each of 1

₹ 38,844.24

In Stock

Quantity

1

Base Price: ₹ 38,844.24

GST (18%): ₹ 6,991.963

Total Price: ₹ 45,836.203

Antigen

MTCO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

mt-Co1

Gene Alias

Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17708, 26195

Content And Storage

-20°C

Form

Lyophilized

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.

P00397, P05503

Gene Symbols

mt-Co1

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse MTCO1 (501-514aa PYHTFEEPTYVKVK).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Cytochrome c oxidase subunit I (CO1 or MTCO1) is 1 of 3 mitochondrial DNA (mtDNA) encoded subunits (MTCO1, MTCO2, MTCO3) of respiratory Complex IV
  • Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation
  • It is composed of 13 polypeptides
  • Subunits I, II, and III (MTCO1, MTCO2, MTCO3) are encoded by mtDNA while subunits IV, Va, Vb, VIa, VIb, VIc, VIIa, VIIb, VIIc, and VIII are nuclear encoded
  • The cytochrome c oxidase family of enzymes have 4 redox centers, 2 hemes and 2 copper centers
  • In mitochondrial Complex IV, the 2 hemes are a and a3 and the 2 coppers are CuA and CuB
  • The 2 hemes and CuB are bound to subunit I
  • Acin-Perez et al
  • (2003) identified a cell line containing single and double missense mutations in the cytochrome c oxidase (COX) subunit I gene of mouse mitochondrial DNA
  • And they hypothesized that deleterious mutations can arise and become predominant; cultured cells can maintain several mtDNA haplotypes at stable frequencies; the respiratory chain has little spare COX capacity; and that the size of a cavity in the vicinity of val421 in MTCO1I of animal COX may affect the function of the enzyme.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA579700

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Antigen:
MTCO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
mt-Co1

Gene Alias:
Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17708, 26195

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P00397, P05503

Gene Symbols:
mt-Co1

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse MTCO1 (501-514aa PYHTFEEPTYVKVK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA579703

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Antigen:
MUC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MUC4

Gene Alias:
4933405I11Rik; Ascites sialoglycoprotein; Ascites sialoglycoprotein 1; Ascites sialoglycoprotein 2; ASGP; ASGP1; ASGP-1; ASGP-2; HSA276359; MUC4; MUC-4; mucin 4; mucin 4, ASGP; mucin 4, cell surface associated; mucin 4, tracheobronchial; Mucin4; mucin-4; Mucin-4 alpha chain; Mucin-4 beta chain; Pancreatic adenocarcinoma mucin; pre-sialomucin complex; Psmc; sialomucin ascites sialoglycoprotein-1; sialomucin complex; testis mucin; Tracheobronchial mucin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
303887, 4585

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q63661, Q99102

Gene Symbols:
MUC4

Immunogen:
E.coli-derived human MUC4 recombinant protein (Position: M1249-D1444).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA579704

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Antigen:
MUC5AC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MUC5AC

Gene Alias:
2210005L13Rik; gastric mucin; LeB; lewis B blood group antigen; LOW QUALITY PROTEIN: mucin-5AC; major airway glycoprotein; MGM; MUC5; MUC5AC; MUC-5AC; mucin; mucin 5, subtypes A and C; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5ac; mucin 5AC, oligomeric mucus/gel-forming; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin-5 subtype AC, tracheobronchial; Mucin-5AC; TBM; Tracheobronchial mucin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4586

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P98088

Gene Symbols:
MUC5AC

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Mucin 5AC (552-567aa TMQLFMQLAPKLRGQT).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA579705

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Antigen:
MUC5AC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MUC5AC

Gene Alias:
2210005L13Rik; gastric mucin; LeB; lewis B blood group antigen; LOW QUALITY PROTEIN: mucin-5AC; major airway glycoprotein; MGM; MUC5; MUC5AC; MUC-5AC; mucin; mucin 5, subtypes A and C; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5ac; mucin 5AC, oligomeric mucus/gel-forming; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin-5 subtype AC, tracheobronchial; Mucin-5AC; TBM; Tracheobronchial mucin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4586, 682837

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin)

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
P98088

Gene Symbols:
MUC5AC

Immunogen:
E.coli-derived human Mucin 5AC recombinant protein (Position: D4848-H5030).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG