PIPA579754

NPC1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579754-Each-of-1 In Stock ₹ 39,015.36

PIPA579754 - Each of 1

₹ 39,015.36

In Stock

Quantity

1

Base Price: ₹ 39,015.36

GST (18%): ₹ 7,022.765

Total Price: ₹ 46,038.125

Antigen

NPC1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NPC1

Gene Alias

A430089E03Rik; C85354; Cdig2; D18Ertd139e; D18Ertd723e; FLJ98532; I79_014078; lcsd; Niemann Pick type C1; Niemann-Pick C disease protein; niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick type C1; Niemann-Pick type C1 protein; nmf164; NPC; NPC intracellular cholesterol transporter 1; NPC1; sphingomyelinosis; spm; truncated Niemann-Pick C1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18145, 266732, 4864

Content And Storage

-20°C

Form

Lyophilized

Applications

Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

O15118, O35604

Gene Symbols

NPC1

Immunogen

E. coli-derived human Niemann Pick C1 recombinant protein (Position: A1022-F1278).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Mutations in the Niemann-Pick disease type C1 (NPC1) gene result in a fatal progressive neurodegenerative disorder characterized by an abnormal sequestration of lipids including cholesterol and glycosphingolipids
  • The NPC1 protein is a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain
  • NPC1 transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolyzed and released as free cholesterol
  • NPC1, in addition to FTO, MC4R, and PTER has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations.

Compare Similar Items

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Img

Thermo Scientific

PIPA579754

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Antigen:
NPC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPC1

Gene Alias:
A430089E03Rik; C85354; Cdig2; D18Ertd139e; D18Ertd723e; FLJ98532; I79_014078; lcsd; Niemann Pick type C1; Niemann-Pick C disease protein; niemann-Pick C1 protein; Niemann-Pick disease, type C1; Niemann-Pick type C1; Niemann-Pick type C1 protein; nmf164; NPC; NPC intracellular cholesterol transporter 1; NPC1; sphingomyelinosis; spm; truncated Niemann-Pick C1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18145, 266732, 4864

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O15118, O35604

Gene Symbols:
NPC1

Immunogen:
E. coli-derived human Niemann Pick C1 recombinant protein (Position: A1022-F1278).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579755

--


Antigen:
NPC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPC2

Gene Alias:
2700012J19Rik; AA408070; AU045843; EDDM1; epididymal protein 1; epididymal secretory protein 1; epididymal secretory protein E1; HE1; human epididymis-specific protein 1; mE1; MGC1333; Niemann Pick type C2; niemann Pick type C2 protein homolog; Niemann-Pick disease type C2 protein; Niemann-Pick disease, type C2; Niemann-Pick type C2; NPC intracellular cholesterol transporter 2; Npc2; NP-C2; re1; tissue-specific secretory protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10577

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P61916

Gene Symbols:
NPC2

Immunogen:
A synthetic peptide corresponding to a sequence of human Niemann Pick C2 (KSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVS).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579757

--


Antigen:
Podocin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nphs2

Gene Alias:
AI790225; nephrosis 2 homolog, podocin; nephrosis 2 idiopathic steroid-resistant (podocin); nephrosis 2, idiopathic, steroid-resistant; nephrosis 2, idiopathic, steroid-resistant (podocin); nephrosis 2, podocin; NPHS2; NPHS2 podocin; NPHS2 stomatin family member, podocin; NPHS2, podocin; PDCN; podocin; SRN1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170484, 170672, 7827

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
Q8K4G9, Q91X05, Q9NP85

Gene Symbols:
Nphs2

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human NPHS2 (368-383aa KPVEPLNPKKKDSPML).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579758

--


Antigen:
ANP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPPA

Gene Alias:
Anf; ANP; ATFB6; atrial natriuretic factor; Atrial natriuretic peptide; atriopeptin; Atriopeptin I; Atriopeptin II; Atriopeptin III; Atriopeptin-1; Atriopeptin-2; Atriopeptin-3; ATRST2; Auriculin-A; Auriculin-B; Cardiodilatin; Cardiodilatin-related peptide; cardionatrin; CDD; CDD-ANF; CDP; natriuretic peptide A; Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd); natriuretic peptide precursor A variant 1; natriuretic peptide precursor A variant NPPA-M1; natriuretic peptide precursor A variant NPPA-M2; natriuretic peptide precursor A variant NPPA-M3; natriuretic peptide precursor type A; natriuretic peptide type A; natriuretic peptides A; Nppa; Pnd; Prepronatriodilatin; Pronatriodilatin; RATANF; urodilatin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
230899, 24602

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P01161, P05125

Gene Symbols:
NPPA

Immunogen:
E. coli-derived mouse ANP recombinant protein (Position: N25-R122).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG