PIPA579771

OPA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579771-Each-of-1 In Stock ₹ 39,015.36

PIPA579771 - Each of 1

₹ 39,015.36

In Stock

Quantity

1

Base Price: ₹ 39,015.36

GST (18%): ₹ 7,022.765

Total Price: ₹ 46,038.125

Antigen

OPA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OPA1

Gene Alias

1200011N24Rik; AI225888; AI847218; BERHS; Dynamin-like 120 kDa protein, form S1; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; EMBL:AAI11072.1}; hypothetical protein; KIAA0567; Large GTP-binding protein; largeG; lilr3; MGM1; mitochondrial dynamin-like GTPase; mitochondrial OPA1; mKIAA0567; MTDPS14; NPG; NTG; OPA1; opa1 {ECO:0000312; OPA1 mitochondrial dynamin like GTPase; OPA1, mitochondrial dynamin like GTPase; optic atrophy 1; optic atrophy 1 (autosomal dominant); optic atrophy 1 homolog; optic atrophy 1-like protein; optic atrophy protein 1; Optic atrophy protein 1 homolog; RCJMB04_1m16; RN protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

171116, 4976, 74143

Content And Storage

-20°C

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

O60313, P58281, Q2TA68

Gene Symbols

OPA1

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human OPA1 (919-955aa EDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEA).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • OPA1 is a dynamin-related GTPase that is critical for the maintenance of mitochondrial morphology and mtDNA
  • The most commonly associated phenotype with OPA1 mutations is heterozygous optic atrophy, a heterozygous dominant trait that causes reduced visual clarity and sometimes blindness
  • The disease usually begins in childhood and increases in severity throughout the life of affected individuals
  • Usually, this phenotype is attributed to the degeneration of optic nerve fibers
  • Interestingly, the same type of nerve degeneration seems to be partially causative of certain schizophrenia characteristics
  • OPA1 dysfunction also seems to be implicated in this case; mitochondrial networks associated with critical nerves seem to link schizophrenia and OPA1
  • The dysfunction is associated with issues with apoptosis and normal cellular metabolic regulation, all regulated through OPA1.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA579771

--


Antigen:
OPA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OPA1

Gene Alias:
1200011N24Rik; AI225888; AI847218; BERHS; Dynamin-like 120 kDa protein, form S1; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; EMBL:AAI11072.1}; hypothetical protein; KIAA0567; Large GTP-binding protein; largeG; lilr3; MGM1; mitochondrial dynamin-like GTPase; mitochondrial OPA1; mKIAA0567; MTDPS14; NPG; NTG; OPA1; opa1 {ECO:0000312; OPA1 mitochondrial dynamin like GTPase; OPA1, mitochondrial dynamin like GTPase; optic atrophy 1; optic atrophy 1 (autosomal dominant); optic atrophy 1 homolog; optic atrophy 1-like protein; optic atrophy protein 1; Optic atrophy protein 1 homolog; RCJMB04_1m16; RN protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171116, 4976, 74143

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
O60313, P58281, Q2TA68

Gene Symbols:
OPA1

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human OPA1 (919-955aa EDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEA).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579773

--


Antigen:
Oncostatin M

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OSM

Gene Alias:
MGC20461; OncoM; oncostatin M; oncostatin-M; OSM

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5008

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P13725

Gene Symbols:
OSM

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Oncostatin M (181-198aa ASDAFQRKLEGCRFLHGY).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579774

--


Antigen:
Oncostatin M

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OSM

Gene Alias:
MGC20461; OncoM; oncostatin M; oncostatin-M; OSM

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5008

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P13725

Gene Symbols:
OSM

Immunogen:
E. coli-derived human Oncostatin M recombinant protein (Position: A26-R220).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579775

--


Antigen:
Oncostatin M

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OSM

Gene Alias:
MGC20461; OncoM; oncostatin M; oncostatin-M; OSM

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18413, 289747

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P53347, Q65Z15

Gene Symbols:
OSM

Immunogen:
E. coli-derived mouse Oncostatin M recombinant protein (Position: N25-R206).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG