PIPA579793

PDCD4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579793-Each-of-1 In Stock ₹ 38,844.24

PIPA579793 - Each of 1

₹ 38,844.24

In Stock

Quantity

1

Base Price: ₹ 38,844.24

GST (18%): ₹ 6,991.963

Total Price: ₹ 45,836.203

Antigen

PDCD4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PDCD4

Gene Alias

D19Ucla1; death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; Pdcd4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; Protein 197/15a; protein MA-3; RP11-348N5.4; Tis; topoisomerase-inhibitor suppressed protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27250

Content And Storage

-20°C

Form

Lyophilized

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and no preservative

Gene Accession No.

Q53EL6

Gene Symbols

PDCD4

Immunogen

E. coli-derived human PDCD4 recombinant protein (Position: E346-L446).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation
  • During this process, the expression patterns of numerous genes are radically altered
  • One such gene is the programmed cell death protein 4 (PDCD4), whose expression was found to be upregulated in all cell lines following the onset of apoptosis
  • PDCD4 encodes a tumor suppressor protein whose expression is lost in carcinomas of breast, colon, lung and prostate
  • It can bind to and inhibit the helicase activity of the eukaryotic translation initiation factor 4A and inhibit the transactivation and transformation mediated by the transcription factor AP-1
  • The kinase Akt regulates PDCD4 by phosphorylation, decreasing the ability of PDCD4 to interfere with the transactivation of AP-1-responsive promoter by c-Jun
  • There are two known isoforms of PDCD4.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA579793

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Antigen:
PDCD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDCD4

Gene Alias:
D19Ucla1; death up-regulated gene protein; death-upregulated; Dug; H731; Ma3; MGC33046; MGC33047; Neoplastic transformation inhibitor protein; nuclear antigen H731; Nuclear antigen H731-like; Pdcd4; programmed cell death 4; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; Protein 197/15a; protein MA-3; RP11-348N5.4; Tis; topoisomerase-inhibitor suppressed protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27250

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
Q53EL6

Gene Symbols:
PDCD4

Immunogen:
E. coli-derived human PDCD4 recombinant protein (Position: E346-L446).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579795

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Antigen:
PDE4D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pde4d

Gene Alias:
9630011N22Rik; ACRDYS2; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D; cAMP-specific phosphodiesterase PDE4D6; cAMP-specific phosphodiesterase splice variant PDE4D8; cyclic AMP specific phosphodiesterase PDE4D5A; DKFZp686M11213; Dpde3; dunce; FLJ97311; HGNC:8783; HS PDE4DN2; HSPDE4D; PDE43; Pde4d; PDE4D3; PDE4D7; PDE4DN2; phosphodiesterase 4D; Phosphodiesterase 4D cAMP-specific (dunce; phosphodiesterase 4D, cAMP specific; phosphodiesterase 4D, cAMP-specific; Phosphodiesterase 4D, cAMP-specific (dunce; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); STRK1; testicular tissue protein Li 136

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238871, 24627, 5144

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P14270, Q01063, Q08499

Gene Symbols:
Pde4d

Immunogen:
E. coli-derived human PDE4D recombinant protein (Position: H466-Q709).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579796

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Antigen:
PDE5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pde5a

Gene Alias:
Cgbpde; CGB-PDE; cGMP-binding cGMP specific phosphodiesterase 5A2; cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase; cGMP-binding cGMP-specific phosphodiesterase; cGMP-binding/cGMP-specific phosphodiesterase; cGMP-specific 3',5'-cyclic phosphodiesterase; cGMP-specific phosphodiesterase PDE5A2; cGMP-specific phosphodiesterase type 5A; CN5A; Cn5n; PDE5; PDE5A; Pde5a1; PDE5A2; phosphodiesterase 5A; phosphodiesterase 5A, cGMP-specific; phosphodiesterase isozyme 5; phosphodiesterase type 5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171115, 8654

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O54735, O76074

Gene Symbols:
Pde5a

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human PDE5A (20-63aa QKQQQRDQDSVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVH).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA579797

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Antigen:
PDK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDK1

Gene Alias:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial; B830012B01; D530020C15Rik; isoenzyme 1; kinase isoenzyme 1; lipoamide; mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; PDH kinase 1; PDHK1; PDK p48; Pdk1; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 1; Pyruvate dehydrogenase kinase isoform 1; pyruvate dehydrogenase kinase, isoenzyme 1; pyruvate dehydrogenase kinase, isozyme 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116551, 228026, 5163

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q15118, Q63065, Q8BFP9

Gene Symbols:
PDK1

Immunogen:
E. coli-derived human PDK1 recombinant protein (Position: V107-Y336).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG