PIPA579886

PROX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA579886-Each-of-1 In Stock ₹ 39,785.40

PIPA579886 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

PROX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Prox1

Gene Alias

A230003G05Rik; homeobox prospero-like protein PROX1; prospero homeobox 1; prospero homeobox protein 1; prospero-related homeobox 1; Prox 1; PROX1; PROX-1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19130, 305066, 5629

Content And Storage

-20°C

Form

Lyophilized

Applications

Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.

P48437, Q92786

Gene Symbols

Prox1

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human PROX1 (346-359aa KHLAETLKQELNTA).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • The expression pattern of the Prox1 homeo box gene suggests that it has a role in a variety of embryonic tissues, including lens
  • Analysis of mRNA reveals that Prox mRNA is present in many different human tissues and that lens demonstrated the highest level
  • Homozygous Prox1-null mice die at midgestation from multiple developmental defects, and a targeted effect on lens development has been reported
  • Prox1 inactivation caused abnormal cellular proliferation, downregulated expression of the cell cycle inhibitors Cdkn1b and Cdkn1c, misexpression of E-cadherin, and excessive apoptosis
  • Consequently, mutant lens cells failed to polarize and elongate properly, resulting in a hollow lens
  • The Prox1 gene is expressed in a subpopulation of endothelial cells that by budding and sprouting give rise to the lymphatic system
  • Prox1 appears to be a specific and required regulator of the development of the lymphatic system
  • Prox1 also has been document to be required for hepatocyte migration in the mouse
  • Loss of Prox1 results in a smaller liver with a reduced population of clustered hepatocytes
  • The homeodomain protein Prox1 regulates the egress of progenitor cells from the cell cycle in the embryonic mouse retina
  • Cells lacking Prox1 are less likely to stop dividing, and ectopic expression of Prox1 forces progenitor cells to exit the cell cycle
  • Prox1 acts as a key participant in progenitor-cell proliferation and cell-fate determination in the vertebrate retina.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA579886

--


Antigen:
PROX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Prox1

Gene Alias:
A230003G05Rik; homeobox prospero-like protein PROX1; prospero homeobox 1; prospero homeobox protein 1; prospero-related homeobox 1; Prox 1; PROX1; PROX-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19130, 305066, 5629

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P48437, Q92786

Gene Symbols:
Prox1

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human PROX1 (346-359aa KHLAETLKQELNTA).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579887

--


Antigen:
PRX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRX

Gene Alias:
CMT4F; KIAA1620; L-Periaxin; periaxin; PRX

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19153, 57716, 78960

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O55103, Q63425, Q9BXM0

Gene Symbols:
PRX

Immunogen:
E. coli-derived human PRX recombinant protein (Position: M1-K91).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579888

--


Antigen:
PSAT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSAT1

Gene Alias:
D8Ertd814e; endometrial progesterone-induced protein; EPIP; NLS2; Phosphohydroxythreonine aminotransferase; phosphoserine aminotransferase; phosphoserine aminotransferase 1; PSA; Psa1; Psat; Psat1; PSATD

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107272, 293820, 29968

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q99K85, Q9Y617

Gene Symbols:
PSAT1

Immunogen:
E. coli-derived human PSAT1 recombinant protein (Position: Q276-L370).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579889

--


Antigen:
PSD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSD

Gene Alias:
1110007H17Rik; A930015K15; EFA6; EFA6A; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6; Exchange factor for ARF6; Exchange factor for ARF6 A; KIAA2011; mKIAA2011; PH and SEC7 domain-containing protein 1; pleckstrin and Sec7 domain containing; pleckstrin and Sec7 domain containing homolog; pleckstrin homology and SEC7 domain-containing protein 1; pleckstrin-Sec7 domains-containing; Psd; Psd1; Psdl; TYL

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171381, 5662, 73728

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
A5PKW4, Q5DTT2, Q9ESQ7

Gene Symbols:
PSD

Immunogen:
E. coli-derived human PSD recombinant protein (Position: T536-K803).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG