PIPA579895

PTPN2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA579895-Each-of-1 In Stock ₹ 39,785.40

PIPA579895 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

PTPN2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPN2

Gene Alias

AI325124; hypothetical protein LOC540888; MPTP; protein tyrosine phosphatase non-receptor type 2; protein tyrosine phosphatase, non-receptor type 2; protein-tyrosine phosphatase PTP-2; Protein-tyrosine phosphatase PTP-S; PTN2; PTPN 2; PTPN2; Ptpt; T cell protein-tyrosine phosphatase; TC PTP; T-cell protein tyrosine phosphatase; T-cell protein-tyrosine phosphatase; TCELLPTP; TCPTP; TC-PTP; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

117063, 5771

Content And Storage

-20°C

Form

Lyophilized

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

P17706, P35233

Gene Symbols

PTPN2

Immunogen

E.coli-derived human TCPTP recombinant protein (Position: M1-C330).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • T-cell protein tyrosine phosphatase (TC-PTP), also known as PTPT and PTPN2, is an enzyme that removes phosphate groups covalently attached to tyrosine residues in proteins
  • This enzyme has two C-terminal end splice variants with distinctly different subcellular localizations
  • The shorter 45 kilodalton isoform is exclusively nuclear in resting cells, but redistrubutes to the cytosol upon stimulation with growth factors and cellular stress
  • The longer 48 kilodalton isoform is exclusively found in the endoplasmic reticulum 3 and seems to have distinctly different physiologic substrates from the smaller isoform
  • Although found in many cell types and tissues, TC-PTP is particularly prominent in hemopoietic cell types
  • Knockout mice lacking TC-PTP are born viable but die 3 to 5 weeks after birth of erythropoietic and lymphopoietic deficits 7, indicating a critical role for TC-PTP in bone marrow maturation
  • TC-PTP will dephosphorylate a wide range of phosphoproteins, such as p52 Shc 6 and receptors for EGF 1, Insulin 8 and growth hormone.

Compare Similar Items

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Thermo Scientific

PIPA579895

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Antigen:
PTPN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN2

Gene Alias:
AI325124; hypothetical protein LOC540888; MPTP; protein tyrosine phosphatase non-receptor type 2; protein tyrosine phosphatase, non-receptor type 2; protein-tyrosine phosphatase PTP-2; Protein-tyrosine phosphatase PTP-S; PTN2; PTPN 2; PTPN2; Ptpt; T cell protein-tyrosine phosphatase; TC PTP; T-cell protein tyrosine phosphatase; T-cell protein-tyrosine phosphatase; TCELLPTP; TCPTP; TC-PTP; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117063, 5771

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P17706, P35233

Gene Symbols:
PTPN2

Immunogen:
E.coli-derived human TCPTP recombinant protein (Position: M1-C330).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA579896

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Antigen:
PTPN22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptpn22

Gene Alias:
70zpep; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; lymphoid-specific protein tyrosine phosphatase; LyP; LYP1; LYP2; PEP; PEST domain-enriched tyrosine phosphatase; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; Ptpn22; PTPN8; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 22

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19260, 26191, 295338

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P29352, Q9Y2R2

Gene Symbols:
Ptpn22

Immunogen:
E. coli-derived mouse PTPN22 recombinant protein (Position: M1-Q309).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA579898

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Antigen:
PTPRF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPRF

Gene Alias:
AA591035; BNAH2; FLJ43335; FLJ45062; FLJ45567; LAR; LAR protein; LARFN5C; LARS; LCA homolog; LCA-homolog; leukocyte antigen-related (LAR) PTP receptor; leukocyte antigen-related tyrosine phosphatase; leukocyte common antigen related; protein tyrosine phosphatase receptor-type F; protein tyrosine phosphatase, receptor type F; protein tyrosine phosphatase, receptor type, F; protein tyrosine phosphatase, receptor type, F polypeptide; Ptprf; PTPRF protein; receptor-linked protein-tyrosine phosphatase LAR; receptor-type tyrosine-protein phosphatase F; RPTP-LAR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5792

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P10586

Gene Symbols:
PTPRF

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human LAR (1167-1203aa EQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA579899

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Antigen:
Paxillin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PXN

Gene Alias:
adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
360820, 5829

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P49023, Q66H76

Gene Symbols:
PXN

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminal of human Paxillin (456-472aa HEKDGKAYCRKDYFDMF).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG